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4-piperidinecarboxylic acid (CID 3773) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(260)
 
 
Inconclusive(20)
 
 
Unspecified(53)
 
 
Top Targets:
Neur chan LBD(22)
 
 
Neur chan mem..(11)
 
 
p450(9)
 
 
HSD10-like SD..(8)
 
 
7TM GPCR Srx(7)
 
 
 
BioAssay Types:
Confirmatory(233)
 
 
 
 
Literature(62)
 
 
 
 
Screening(26)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(204)
 
 
 
 
EC50(18)
 
 
 
IC50(13)
 
 
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 264    Data Row: 338   Total Pages: 17   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179764]
IC50 0.33Inhibition of [3H]GABA binding to Gamma-aminobutyric acid receptor of rat brain synaptosomal membranes [AID71448, Type: Literature]
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2
[SID103179764]
IC50 15.8489Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
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3
[SID103179764]
IC50 15.8489Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
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4
[SID103179764]
IC50 15.8489Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay [AID524795, Type: Literature]
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5
[SID103179764]
IC50 15.8489Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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6
[SID103179764]
IC50 94.1Inhibitory concentration required to inhibit [3H]strychnine binding to N-methyl-D-aspartate glutamate receptor 1 [AID143614, Type: Literature]
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7
[SID103179764]
EC50 160Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-6-beta-3-gamma-2 [AID73542, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-3 [gi:120773]
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8
[SID103179764]
EC50 160Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-6-beta-3-gamma-2 [AID73542, Type: Literature]Gamma-aminobutyric acid receptor subunit gamma-2 [gi:116242488]
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9
[SID103179764]
EC50 160Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-6-beta-3-gamma-2 [AID73542, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-6 [gi:126302548]
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10
[SID103179764]
EC50 300Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-4-beta-3-gamma-2 [AID73365, Type: Literature]Gamma-aminobutyric acid receptor subunit gamma-2 [gi:116242488]
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11
[SID103179764]
EC50 300Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-4-beta-3-gamma-2 [AID73365, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-4 [gi:206729865]
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12
[SID103179764]
IC50 300Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane [AID180670, Type: Literature]Sodium- and chloride-dependent GABA transporter 1 [gi:128609]
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13
[SID103179764]
IC50 300Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane [AID180670, Type: Literature]Sodium- and chloride-dependent betaine transporter [gi:1352527]
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14
[SID103179764]
IC50 300Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane [AID180670, Type: Literature]Sodium- and chloride-dependent GABA transporter 2 [gi:400624]
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15
[SID103179764]
IC50 300Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane [AID180670, Type: Literature]Sodium- and chloride-dependent GABA transporter 3 [gi:400626]
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16
[SID103179764]
EC50 300Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-4-beta-3-gamma-2 [AID73365, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-3 [gi:120773]
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17
[SID103179764]
EC50 370Effective dose for agonist activity on activity on human Gamma-aminobutyric acid A receptor alpha-3-beta-3-gamma-2 expressed in Xenopus oocytes [AID73238, Type: Literature]
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18
[SID103179764]
EC50 420Agonist activity on human Gamma-aminobutyric acid A receptor alpha-2-beta-3-gamma-2 expressed in Xenopus oocytes [AID73084, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-3 [gi:120773]
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19
[SID103179764]
EC50 420Agonist activity on human Gamma-aminobutyric acid A receptor alpha-2-beta-3-gamma-2 expressed in Xenopus oocytes [AID73084, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-2 [gi:126302547]
View
20
[SID103179764]
EC50 420Agonist activity on human Gamma-aminobutyric acid A receptor alpha-2-beta-3-gamma-2 expressed in Xenopus oocytes [AID73084, Type: Literature]Gamma-aminobutyric acid receptor subunit gamma-2 [gi:116242488]
View