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(5-hydroxy-1H-indol-3-yl)acetate (CID 3772821) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(3)
 
 
Top Targets:
Peptidase S29(3)
 
 
BioAssay Types:
Screening(6)
 
 
 
Literature(2)
 
 
Confirmatory(1)
 
 
BioActivity Types:
Kd(2)
 
 
IC50(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 9   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170481992]
Kd 28Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Human Ppargamma Ligand-Binding Domain In Complex With 5-Hydroxy-Indole Acetate [gi:315364406]
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2
[SID170481992]
Kd 28Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Human Ppargamma Ligand-Binding Domain In Complex With 5-Hydroxy-Indole Acetate [gi:315364406]
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3
[SID163603258]
HDA (HCV NS3h) Average IC50 69.3Fluorescence polarization based biochemical confirmatory assay of ChemBridge compounds to identify inhibitors of hepatitis C non-structural protein 3 helicase [AID743264, Type: confirmatory]NS3 [Hepatitis C virus] [gi:125541954]
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4
[SID163603258]
Fluorescence polarization based primary biochemical high throughput screening assay of ChemBridge compounds to identify inhibitors of hepatitis C virus non-structural protein 3 helicase [AID687043, Type: screening]NS3 [Hepatitis C virus] [gi:125541954]
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5
[SID163603258]
Fluorescence polarization based confirmation biochemical high throughput screening assay of ChemBridge compounds to identify inhibitors of hepatitis C non-structural protein 3 helicase [AID720485, Type: screening]NS3 [Hepatitis C virus] [gi:125541954]
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6
[SID163603258]
Biochemical high throughput counterscreening assay of selected ChemBridge compounds for inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3): fluorescence polarization based assay to identify compounds that inhibit the ability of E. coli ssDNA binding protein to bind DNA [AID720486, Type: screening]
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7
[SID163603258]
Fluorescence-based counterscreen assay for HCV NS3 helicase inhibitors of selected ChemBridge compounds: biochemical high-throughput screening assay to identify compounds that enhance or quench fluorescence of a Cy5-labeled oligonucleotide bound to E. coli SSB [AID720487, Type: screening]
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8
[SID163603258]
Fluorescence-based counterscreen assay for HCV NS3 helicase inhibitors of a ChemBridge library: biochemical high-throughput screening assay to identify compounds that enhance or quench Cy5 fluorescence [AID720488, Type: screening]
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9
[SID163603258]
Fluorescence-based confirmation counterscreen assay for HCV NS3 helicase inhibitors of a ChemBridge library: biochemical high-throughput screening assay to identify compounds that enhance or quench fluorescence of a Cy5-DNA-NS3h complex [AID720489, Type: screening]
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