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Ribavirin (CID 37542) - Compound BioActivity Data
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BioActivity Outcomes:
Active(318)
 
 
Inactive(1222)
 
 
Inconclusive(138)
 
 
Unspecified(1565)
 
 
Top Targets:
7TM GPCR Srx(48)
 
 
 
 
7TM GPCR Srsx(38)
 
 
 
NR LBD PPAR(30)
 
 
 
NR LBD ER(19)
 
 
 
 
 
NR LBD AR(17)
 
 
 
 
BioAssay Types:
Literature(1735)
 
 
 
 
 
Confirmatory(802)
 
 
 
 
 
Screening(522)
 
 
 
 
Summary(49)
 
 
 
 
BioActivity Types:
Potency(586)
 
 
 
 
 
EC50(333)
 
 
 
 
 
IC50(243)
 
 
 
 
 
AC50(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2964    Data Row: 3243   Total Pages: 163   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103619997]
EC50 0.005Effective concentration required to inhibit Herpes simplex virus-1(HSV-1) / thymine kinase deficient (TK-)B2006 / VMW1837 induced cytopathicity by 50% in E6SM cell lines [AID63915, Type: Literature]
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2
[SID103619997]
EC50 0.094Antiviral activity against Influenza B virus (B/HK/5/72) infected in MDCK cells assessed as virus-induced cytopathic effect after 3 days by microscopic analysis [AID717172, Type: Literature]
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3
[SID103619997]
EC50 0.14Antiviral activity against Influenza B virus (B/HK/5/72) infected in MDCK cells assessed as virus-induced cytopathic effect after 3 days by MTS assay [AID717171, Type: Literature]
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4
[SID103619997]
IC50 0.41Antiviral activity against Influenza A virus A/Hong Kong/8/68(H3N2) infected in dog MDCK cells after 3 days by CPE assay [AID751301, Type: Literature]
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5
[SID144203810]
Potency-Replicate_1 0.6682qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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6
[SID144203810]
Potency-Replicate_1 0.7498qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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7
[SID103619997]
IC50 1Inhibition of IMPDH in mouse L1210 cells assessed as formation of [2,8-3H]hypoxanthine from [2,8-3H]IMP after 20 to 60 mins [AID665016, Type: Literature]
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8
[SID103619997]
IC50 1Inhibition of IMPDH in human CEM cells assessed as formation of [2,8-3H]hypoxanthine from [2,8-3H]IMP after 20 to 60 mins [AID665017, Type: Literature]
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9
[SID8139972]
Potency 1.0323qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID103619997]
EC50 1.1Antiviral activity against influenza A virus H3N3 subtype infected in dog MDCK cells assessed as reduction of virus-induced cytopathogenicity by MTS assay [AID768188, Type: Literature]
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11
[SID103619997]
EC50 1.1Inhibition of West Nile virus VLP replicon in BHK21 cell line [AID261589, Type: Literature]
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12
[SID144203810]
Potency 1.1582qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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13
[SID144203810]
Potency 1.1582qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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14
[SID8139972]
Potency 1.4581qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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15
[SID103619997]
EC50 1.5Anti BVDV activity in MDBK (Madin-darby bovine kidney) cells [AID246174, Type: Literature]
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16
[SID103619997]
EC50 1.5Effective concentration required to inhibit respiratory synaptial(RSV) virus-induced cytopathicity by 50% in HeLa cell lines [AID86683, Type: Literature]
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17
[SID144208165]
Potency-Replicate_1 1.6187qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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18
[SID144203810]
Potency-Replicate_1 1.6785qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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19
[SID103619997]
IC50 1.9Antiinfluenza activity against influenza A virus H1N1 infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect after 36 hrs [AID648646, Type: Literature]
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20
[SID103619997]
EC50 2Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as inhibition of plaque formation after 12 hrs by toluidine blue staining assay [AID1066048, Type: Literature]
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