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Indoprofen (CID 3718) - Compound BioActivity Data
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BioActivity Outcomes:
Active(46)
 
 
Inactive(911)
 
 
Inconclusive(61)
 
 
Unspecified(27)
 
 
Top Targets:
7TM GPCR Srsx(23)
 
 
7TM GPCR Srx(23)
 
 
Bcl-2 like(12)
 
 
alkPPc(10)
 
 
NR LBD PPAR(8)
 
 
BioAssay Types:
Screening(532)
 
 
 
 
Confirmatory(331)
 
 
 
 
 
Literature(103)
 
 
 
 
Summary(15)
 
 
 
 
BioActivity Types:
Potency(284)
 
 
 
 
 
IC50(39)
 
 
EC50(9)
 
 
 
Ki(3)
 
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 837    Data Row: 1045   Total Pages: 53   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179093]
Ki 0.00052Displacement of [125I]TZDM from beta amyloid 42 fibril [AID314380, Type: Literature]
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2
[SID144204869]
Potency-Replicate_1 0.0596qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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3
[SID11532964]
Potency 0.0891qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
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4
[SID144204869]
Potency-Replicate_1 0.1188qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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5
[SID26748086]
Potency 0.1811Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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6
[SID11532964]
Potency 0.2685qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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7
[SID11532964]
Potency 0.3162qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]ras-related protein Rab-9A [Homo sapiens] [gi:4759012]
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8
[SID144204869]
ATAD5 Potency (uM) 0.595572qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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9
[SID144204869]
Potency-Replicate_1 0.5956qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
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10
[SID26748086]
Potency 1.2589qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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11
[SID103179093]
Ki 1.27Displacement of 1-anilinonaphthalene-8-sulphonic acid from rat recombinant L-FABP high binding affinity site expressed in Escherichia coli BL21 by competitive fluorescence displacement assay [AID407366, Type: Literature]Fatty acid-binding protein, liver [gi:119810]
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12
[SID11532964]
EC50 1.518Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response [AID1241, Type: confirmatory]nuclear factor NF-kappa-B p105 subunit isoform 1 [Homo sapiens] [gi:34577122]
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13
[SID11532964]
EC50 1.518Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response [AID1241, Type: confirmatory]transcription factor p65 isoform 1 [Homo sapiens] [gi:223468676]
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14
[SID26748086]
Potency 1.7783qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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15
[SID11532964]
Potency 2.2387qHTS Assay Multiplex Screening to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (Protease relase) [AID2669, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
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16
[SID26748086]
Potency 3.9811VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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17
[SID11532964]
Potency 5.0119qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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18
[SID11532964]
Potency 6.3096qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode) [AID624417, Type: confirmatory]glp-1 receptor, partial [Homo sapiens] [gi:1724069]
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19
[SID144204869]
Potency-Replicate_1 7.4978qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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20
[SID144204869]
TR Potency (uM) 7.79114qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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