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Diflubenzuron (CID 37123) - Compound BioActivity Data
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BioActivity Outcomes:
Active(13)
 
 
Inactive(246)
 
 
Inconclusive(30)
 
 
Unspecified(55)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD ER(16)
 
 
 
 
NR LBD AR(16)
 
 
 
NR LBD TR(12)
 
 
NR LBD VDR(11)
 
 
 
BioAssay Types:
Confirmatory(226)
 
 
 
 
Literature(48)
 
 
 
 
Summary(48)
 
 
 
 
Screening(3)
 
 
BioActivity Types:
Potency(257)
 
 
 
 
IC50(2)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 243    Data Row: 344   Total Pages: 18   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103230247]
IC50 0.01905Inhibition of chitin synthesis in 20-hydroxyecdysone-stimulated Chilo suppressalis (rice stem borer) larval integument assessed as inhibition of N-acetyl-{1-14C]-glucosamine after 72 hr by liquid scintillation counting in presence of piperonyl butoxide [AID1108928, Type: confirmatory]
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2
[SID103230247]
EC50 0.02Insecticidal activity against Chilo suppressalis (rice stem borer) larvae assessed as inhibition of incorporation of N-acetyl-[1-14C]glucosamine [AID1099671, Type: confirmatory]
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3
[SID103230247]
IC50 0.02042Inhibition of chitin synthesis in 20-hydroxyecdysone-stimulated Chilo suppressalis (rice stem borer) larval integument assessed as inhibition of N-acetyl-{1-14C]-glucosamine after 72 hr by liquid scintillation counting [AID1108932, Type: confirmatory]
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4
[SID144209167]
Potency-Replicate_1 0.0971qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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5
[SID144213455]
AhR Potency (uM) 0.142208qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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6
[SID144209167]
AhR Potency (uM) 0.331493qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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7
[SID144213455]
Potency-Replicate_1 0.6113qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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8
[SID144213455]
Potency-Replicate_1 2.4337qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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9
[SID26753710]
Potency 2.5119qHTS assay for environmental chemicals that activate the Aryl hydrocarbon Receptor (AhR) signaling pathway [AID651777, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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10
[SID26753710]
Potency 15.8489qHTS assay for small molecule agonists of retinoid X receptor alpha signaling [AID588544, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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11
[SID103230247]
Insecticidal activity against adult of Cacopsylla melanoneura in apple plant assessed as reduction of progeny per female at 300 g/ha treated for 14 days measured after 7 days [AID1111272, Type: Literature]
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12
[SID103230247]
Insecticidal activity against adult of Cacopsylla melanoneura in apple plant assessed as reduction of progeny per female at 300 g/ha treated for 7 days measured after 7 days [AID1111275, Type: Literature]
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13
[SID103230247]
Insecticidal activity against adult of Cacopsylla melanoneura in apple plant assessed as reduction of progeny per female at 300 g/ha treated for 1 hr measured after 7 days [AID1111278, Type: Literature]
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14
[SID103230247]
Insecticidal activity against adult of Cacopsylla melanoneura in apple plant assessed as overwintered female mortality at 300 g/ha treated for 1 hr measured after 3 days relative to control [AID1111279, Type: Literature]
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15
[SID103230247]
Insecticidal activity against adult of Cacopsylla melanoneura in apple plant assessed as overwintered female mortality at 300 g/ha treated for 1 hr measured after 1 day relative to control [AID1111280, Type: Literature]
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16
[SID103230247]
Resistance ratio, ratio of LC50 for third-instar larvae of fufenozide-resistant Plutella xylostella (diamondback moth) to LC50 for third-instar larvae of fufenozide-susceptible Plutella xylostella [AID1112037, Type: Literature]
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17
[SID103230247]
Insecticidal activity against third-instar larvae of fufenozide-susceptible Plutella xylostella (diamondback moth) assessed as mortality by leaf-dip bioassay method [AID1112038, Type: Literature]
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18
[SID103230247]
Insecticidal activity against third-instar larvae of fufenozide-resistant Plutella xylostella (diamondback moth) assessed as mortality by leaf-dip bioassay method [AID1112039, Type: Literature]
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19
[SID103230247]
Toxicity in Daphnia magna assessed as mobilization concentration measured up to 48 hr [AID1109440, Type: other]
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20
[SID103230247]
Insecticidal activity against second or third-instar Plutella xylostella (diamondback moth) in compound treated cabbage leaves at 26 degC [AID1109441, Type: other]
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