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Gallic Acid (CID 370) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(99)
 
 
Inactive(393)
 
 
Inconclusive(107)
 
 
Unspecified(145)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD ER(18)
 
 
 
 
NR LBD AR(16)
 
 
 
NR LBD TR(12)
 
 
 
NR LBD VDR(12)
 
 
 
 
BioAssay Types:
Confirmatory(365)
 
 
 
 
Literature(279)
 
 
 
 
 
Summary(48)
 
 
 
 
Screening(7)
 
 
BioActivity Types:
Potency(360)
 
 
 
 
IC50(53)
 
 
 
 
 
Ki(13)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 540    Data Row: 744   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389871]
Potency 0.0501qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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2
[SID17389871]
Potency 0.0501qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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3
[SID26747307]
Potency 0.3548qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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4
[SID103217472]
IC50 0.53Antioxidant activity assessed as superoxide anion radical scavenging activity [AID311581, Type: Literature]
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5
[SID26747307]
Potency 0.5805qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID26747307]
Potency 0.92qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID103217472]
IC50 1.01Antioxidant activity assessed by superoxide anion scavenging assay [AID401336, Type: Literature]
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8
[SID26747307]
Potency 1.2589qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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9
[SID26747307]
Potency 1.9953qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization [AID1468, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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10
[SID17389871]
Potency 1.9953qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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11
[SID26747307]
Potency 1.9953qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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12
[SID103217472]
Ki 2.25Inhibition of human CA2 by stopped-flow CO2 hydration assay [AID462271, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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13
[SID103217472]
IC50 2.7Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins [AID377830, Type: Literature]
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14
[SID26747307]
Potency 3.1623qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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15
[SID103217472]
Ki 3.2Inhibition of human CA1 by stopped-flow CO2 hydration assay [AID462270, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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16
[SID26747307]
Potency 3.5397qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia [AID2451, Type: confirmatory]Chain A, Structure Of Giardia Fructose-1,6-biphosphate Aldolase In Complex With Phosphoglycolohydroxamate [gi:122920737]
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17
[SID26747307]
Potency 3.9811Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization [AID1463, Type: confirmatory]
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18
[SID103217472]
Ki 4.08Inhibition of human CA5A by stopped-flow CO2 hydration assay [AID462274, Type: Literature]Carbonic anhydrase 5A, mitochondrial [gi:461680]
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19
[SID103217472]
Ki 4.13Inhibition of Dicentrarchus labrax CA using 4-nitrophenylacetate substrate by esterase assay [AID607497, Type: Literature]Carbonic anhydrase [gi:123910379]
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20
[SID103217472]
EC50 4.2Antioxidant activity assessed as DPPH free radical scavenging activity [AID377909, Type: Literature]
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21
[SID17389871]
Potency 4.2163qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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22
[SID103217472]
IC50 4.75Cytotoxicity against human imatinib-resistant K562 cells [AID732049, Type: Literature]
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23
[SID103217472]
IC50 6DPPH radical scavenging activity in ethanol solution [AID269889, Type: Literature]
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24
[SID103217472]
Ki 6.07Inhibition of human CA7 by stopped-flow CO2 hydration assay [AID462277, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
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25
[SID103217472]
Ki 6.13Inhibition of human CA6 by stopped-flow CO2 hydration assay [AID462276, Type: Literature]Carbonic anhydrase 6 [gi:116241278]
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26
[SID144209713]
Ratio Potency (uM) 6.61026qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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27
[SID103217472]
Ki 6.99Inhibition of human CA9 by stopped-flow CO2 hydration assay [AID462278, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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28
[SID103217472]
Ki 7.03Inhibition of human CA14 by stopped-flow CO2 hydration assay [AID462281, Type: Literature]Carbonic anhydrase 14 [gi:8928036]
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29
[SID26747307]
Potency 7.0795qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 [Homo sapiens] [gi:31542939]
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30
[SID103217472]
IC50 7.3DPPH radical scavenging activity in liposome [AID269890, Type: Literature]
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31
[SID103217472]
Ki 7.49Inhibition of human CA3 by stopped-flow CO2 hydration assay [AID462272, Type: Literature]Carbonic anhydrase 3 [gi:134047703]
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32
[SID103217472]
Ki 7.78Inhibition of human CA12 by stopped-flow CO2 hydration assay [AID462279, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
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33
[SID103217472]
IC50 7.8Antioxidant activity assessed as inhibition of ABTS radical formation for 15 mins by spectrophotometric analysis [AID736486, Type: Literature]
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34
[SID103217472]
IC50 8DPPH radical scavenging activity after 180 mins [AID382837, Type: Literature]
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35
[SID17389871]
Potency 8.4921Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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36
[SID17389871]
Potency 8.9125qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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37
[SID17389871]
Potency 8.9125qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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38
[SID103217472]
Ki 9.8Inhibition of human CA4 by stopped-flow CO2 hydration assay [AID462273, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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39
[SID103217472]
Ki 9.86Inhibition of mouse CA13 by stopped-flow CO2 hydration assay [AID462280, Type: Literature]Carbonic anhydrase 13 [gi:30580372]
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40
[SID103217472]
IC50 9.9Antioxidant activity assessed as inhibition of DPPH radical formation measured every min for 45 mins by spectrophotometric analysis [AID736487, Type: Literature]
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41
[SID103217472]
Ki 9.97Inhibition of human CA5B by stopped-flow CO2 hydration assay [AID462275, Type: Literature]Carbonic anhydrase 5B, mitochondrial [gi:8928041]
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42
[SID26747307]
Potency 10qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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43
[SID17389871]
Potency 10qHTS for Inhibitors of Glutaminase (GLS) [AID624170, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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44
[SID17389871]
Potency 10qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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45
[SID103217472]
IC50 10Cytotoxicity against human Calu6 cells [AID732055, Type: Literature]
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46
[SID26747307]
Potency 10qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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47
[SID26747307]
Potency 11.2202qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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48
[SID17389871]
Potency 12.5893qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature [AID924, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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49
[SID144204640]
Potency-Replicate_1 13.3332qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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50
[SID144204640]
Potency-Replicate_1 13.3332qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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