ifenprodil (CID 3689) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(40)
 
 
Inactive(126)
 
 
Inconclusive(52)
 
 
Unspecified(1)
 
 
Top Targets:
HELICc(4)
 
 
Menin(4)
 
 
NR LBD ROR li..(4)
 
 
NR LBD TR(4)
 
 
Pyr redox dim(4)
 
 
BioAssay Types:
Confirmatory(126)
 
 
 
 
Literature(68)
 
 
 
 
 
Screening(22)
 
 
BioActivity Types:
Potency(124)
 
 
 
 
IC50(1)
 
 
Ki(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 127    Data Row: 219   Total Pages: 5   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID124960908]
Ki 0.015Displacement of [3H]-emopamil from delta(8)-delta(7) sterol isomerase in guinea pig liver membranes [AID634764, Type: Literature]3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase [gi:18202586]
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2
[SID124960908]
IC50 0.1Inhibition of human ERG [AID576612, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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3
[SID124960908]
IC50 0.1Inhibition of human ERG [AID576612, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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4
[SID124960908]
IC50 0.1Inhibition of human ERG [AID576612, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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5
[SID124960908]
IC50 0.1Inhibition of human ERG [AID576612, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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6
[SID124960908]
IC50 0.1Inhibition of human ERG [AID576612, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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7
[SID26751765]
Potency 2.1331Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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8
[SID144204466]
Potency 8.4144qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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9
[SID144204466]
Potency 8.4144qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID144204466]
Potency 8.4144qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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11
[SID90341159]
Potency 11.2202HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Agonists [AID488981, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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12
[SID90341159]
Potency 11.2202HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Agonists [AID488981, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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13
[SID90341159]
Potency 11.2202HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Agonists [AID488981, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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14
[SID90341159]
Potency 11.2202HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Agonists [AID488981, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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15
[SID90341159]
Potency 11.6681Cytometry Cell-Based qHTS for Inhibitors of the mTORC1 Signaling Pathway in MEF cells [AID2668, Type: confirmatory]MTOR gene product [Homo sapiens] [gi:4826730]
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16
[SID90341159]
Potency 11.6681Cytometry Cell-Based qHTS for Inhibitors of the mTORC1 Signaling Pathway in MEF cells [AID2668, Type: confirmatory]MTOR gene product [Homo sapiens] [gi:4826730]
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17
[SID90341159]
Potency 16.3601qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion [AID485298, Type: confirmatory]
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18
[SID90341159]
Potency 20.5878qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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19
[SID29215029]
Potency 20.5878qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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20
[SID50104451]
Potency 20.5878qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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21
[SID50104452]
Potency 20.5878qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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22
[SID26751765]
Potency 20.5878qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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23
[SID144204466]
Potency 21.136qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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24
[SID144204466]
Potency 21.136qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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25
[SID144204466]
Potency 21.136qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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26
[SID90341159]
Potency 23.0999qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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27
[SID26751765]
Potency 25.5748S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]Pmp22 gene product [Rattus norvegicus] [gi:8393992]
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28
[SID26751765]
 qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP) [AID1471, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
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29
[SID26751765]
 qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP) [AID1471, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
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30
[SID103856535]
 Wombat Data for BeliefDocking [AID493017, Type: Literature] [geneid:6531]
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31
[SID103856535]
 Wombat Data for BeliefDocking [AID493017, Type: Literature] [geneid:6531]
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32
[SID103856535]
 Wombat Data for BeliefDocking [AID493017, Type: Literature] [geneid:6531]
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33
[SID103856535]
 Wombat Data for BeliefDocking [AID493017, Type: Literature] [geneid:6531]
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34
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_55, Type: Literature]
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35
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_56, Type: Literature]
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36
[SID85213187]
 Ligands of bioamine (Class A) GPCRs [AID2062, Type: other]
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37
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_38, Type: Literature]
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38
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_39, Type: Literature]
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39
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_40, Type: Literature]
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40
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_36, Type: Literature]
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41
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_53, Type: Literature]
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42
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_2, Type: Literature]
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43
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_3, Type: Literature]
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44
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_4, Type: Literature]
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45
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_5, Type: Literature]
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46
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_6, Type: Literature]
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47
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_8, Type: Literature]
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48
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_12, Type: Literature]
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49
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_16, Type: Literature]
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50
[SID26751765]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_19, Type: Literature]
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