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p-Hydroxyamphetamine (CID 3651) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(13)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srsx(1)
 
 
Bcl-2 like(1)
 
 
MSH6 like(1)
 
 
PTZ00435(1)
 
 
STKc AGC(1)
 
 
BioAssay Types:
Screening(11)
 
 
Literature(3)
 
 
 
BioActivity Types:
Kd(1)
 
 
EC50(1)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 17    Data Row: 17   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103573061]
EC50 0.05Activation of rat TAAR1 expressed in HEK293 cells assessed as accumulation of [3H]cAMP after 1 hr by competitive binding assay [AID635290, Type: Literature]Trace amine-associated receptor 1 [gi:38258290]
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2
[SID48416093]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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3
[SID103573061]
IC50 100Inhibition of BACE1 [AID318155, Type: Literature]
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4
[SID103573061]
Kd 800Binding affinity to BACE1 by surface plasmon resonance method [AID318154, Type: Literature]
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5
[SID443259]
NCI In Vivo Anticancer Drug Screen. Data for tumor model B16 Melanoma (intraperitoneal) in B6D2F1 (BDF1) mice [AID192, Type: other]
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6
[SID443259]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID248, Type: other]
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7
[SID85789278]
Development of IDH1/2 inhibitors (CTD2project) Measured in Biochemical System Using Plate Reader - 2107-01_Inhibitor_SinglePoint_HTS_Activity [AID624101, Type: screening]Isocitrate dehydrogenase 1 (NADP+), soluble [Homo sapiens] [gi:62203298]
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8
[SID85789278]
NSD2 Inhibitors Measured in Biochemical System Using Plate Reader - 2115-01_Inhibitor_SinglePoint_HTS_Activity [AID624260, Type: screening]histone-lysine N-methyltransferase NSD2 isoform 1 [Homo sapiens] [gi:109633019]
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9
[SID85789278]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 [AID2241, Type: screening]Chain A, Human Bcl2-A1 In Complex With Bim-Bh3 Peptide [gi:167013344]
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10
[SID85789278]
Fluorescence Cell-Based Primary HTS to Identify Reactive Oxygen Species Inducers in Cancer Cells Measured in Cell-Based System Using Plate Reader and Imaging Combination - 2044-01_Activator_SinglePoint_HTS_Activity [AID624156, Type: screening]
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11
[SID85789278]
SMM ID4 Measured in Biochemical System Using Small Molecule MicroArray - 2128-01_Other_SinglePoint_HTS_Activity [AID624137, Type: screening]Id4 [Homo sapiens] [gi:881546]
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12
[SID85789278]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of STK33 [AID2330, Type: screening]serine/threonine kinase 33 [Homo sapiens] [gi:12830367]
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13
[SID85789278]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of MITF [AID2240, Type: screening]microphthalmia-associated transcription factor isoform 1 [Homo sapiens] [gi:38156699]
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14
[SID85789278]
Luminescence Cell-Based Primary HTS to Measure Viability of BJeLR cells [AID2275, Type: screening]
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15
[SID85789278]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of the Sonic Hedgehog Signaling Pathway [AID2313, Type: screening]
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16
[SID85789278]
Luminescence Homogenous Primary HTS to Identify Inhibitors of STK33 Activity [AID2322, Type: screening]
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17
[SID85789278]
Fluorescence Cell-Based Primary HTS to Measure Inhibition of Y box Binding Protein 1 Expression [AID434959, Type: screening]
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