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Paclitaxel (CID 36314) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2042)
 
 
Inactive(602)
 
 
Inconclusive(148)
 
 
Unspecified(1274)
 
 
Top Targets:
beta tubulin(42)
 
 
 
 
7TM GPCR Srx(36)
 
 
 
 
ABC MTABC3 MD..(32)
 
 
 
7TM GPCR Srsx(30)
 
 
 
 
alpha tubulin(25)
 
 
 
 
BioAssay Types:
Literature(2667)
 
 
 
 
 
Screening(333)
 
 
 
 
Confirmatory(324)
 
 
 
 
 
Summary(15)
 
 
 
 
BioActivity Types:
IC50(1711)
 
 
 
 
 
Potency(240)
 
 
 
 
 
EC50(48)
 
 
 
 
Kd(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 3859    Data Row: 4066   Total Pages: 82   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID124974065]
GI50 2.4e-06Inhibitory concentration against MBA-MB231 (breast) cells [AID103187, Type: Literature]
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2
[SID124974065]
GI50 9.2e-06Inhibitory concentration against 2008 (ovarian) cells [AID3018, Type: Literature]
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3
[SID124974065]
GI50 1e-05Antiproliferative activity against human A431 cells by SRB assay [AID351333, Type: Literature]
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4
[SID124974065]
GI50 1e-05Antiproliferative activity against human MESSA cells by SRB assay [AID351328, Type: Literature]
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5
[SID124974065]
IC50 1e-05Cytotoxicity against human SW626 cells after 72 hrs by SRB assay [AID334868, Type: Literature]
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6
[SID124974065]
ED50 1.2e-05Growth inhibition of human SW626 cells xenografted in ip dosed NCr nu/nu mouse administered once daily from day 3 to 6 after implantation measured on day 7 by MTT-based hollow-fiber test [AID422136, Type: Literature]
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7
[SID124974065]
GI50 1.5e-05Inhibitory concentration against PC3 (prostrate) cells [AID156638, Type: Literature]
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8
[SID124974065]
IC50 1.6e-05Cytotoxicity against human Hep3B2 cells after 72 hrs by MTS assay [AID617223, Type: Literature]
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9
[SID124974065]
GI50 1.7e-05Growth inhibition of human HBL100 cells [AID626302, Type: Literature]
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10
[SID124974065]
GI50 3.3e-05Growth inhibition of human HeLa cells [AID626303, Type: Literature]
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11
[SID124974065]
IC50 4e-05In vitro cytotoxic activity against uterine sarcoma (MES-SA) cells assayed by inhibition of [3H]-labeled thymidine incorporation [AID106322, Type: Literature]
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12
[SID124974065]
IC50 7e-05Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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13
[SID124974065]
IC50 9e-05Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
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14
[SID124974065]
IC50 9e-05Cytotoxicity expressed as concentration required to inhibit cell growth by 50% on continuous exposure time of 96h in L1210 cell line by MTT assay. [AID98569, Type: Literature]
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15
[SID124974065]
GI50 0.0001Growth inhibitory activity against human cancer cell line in the NCI inverted question marks anticancer drug screening program [AID247402, Type: Literature]
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16
[SID124974065]
CC50 0.0001Cytotoxicity against human KB3 cells [AID415835, Type: Literature]
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17
[SID124974065]
ED50 0.0001Cytotoxicity against human HT-29 cells after 3 days by SRB assay [AID479073, Type: Literature]
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18
[SID124974065]
ED50 0.0001Cytotoxicity against human HT-29 cells after 3 days by sulforhodamine B assay [AID599228, Type: Literature]
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19
[SID124974065]
ED50 0.0001Anticancer activity aganist human HT-29 cells [AID592412, Type: Literature]
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20
[SID124974065]
IC50 0.0001Cytotoxicity against human SKOV3 cells by MTT assay [AID663855, Type: Literature]
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21
[SID124974065]
IC50 0.00014In vitro cytotoxic activity against nonsmall cell lung carcinoma (NCI-H460) cells assayed by inhibition of [3H]-labeled thymidine incorporation [AID145212, Type: Literature]
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22
[SID124974065]
IC50 0.00015Antiproliferative activity against human HT1080 after 48 hrs by SRB assay [AID627401, Type: Literature]
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23
[SID124974065]
IC50 0.00015Antiproliferative activity against human HT1080 cells after 48 hrs by sulforhodamine B assay [AID605766, Type: Literature]
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24
[SID124974065]
GI50 0.00015Growth inhibition of human T47D cells [AID626306, Type: Literature]
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25
[SID124974065]
IC50 0.00015Antiplasmodial activity against Plasmodium falciparum D10 after 72 hrs by SYBR green assay [AID524792, Type: Literature]
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26
[SID124974065]
IC50 0.00015Antiplasmodial activity against Plasmodium falciparum Dd2 after 72 hrs by SYBR green assay [AID524793, Type: Literature]
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27
[SID124974065]
IC50 0.00016In vitro cytotoxic activity against colon adenocarcinoma (HT-29) cells assayed by inhibition of [3H]-labeled thymidine incorporation [AID85754, Type: Literature]
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28
[SID124974065]
IC50 0.0002Cytotoxicity against human Aro cells after 72 hrs by MTT assay [AID302390, Type: Literature]
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29
[SID124974065]
IC50 0.0002Cytotoxicity against human Aro cells by MTT assay [AID261537, Type: Literature]
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30
[SID124974065]
IC50 0.0002Cytotoxicity against human OVCAR-3 cells [AID310993, Type: Literature]
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31
[SID124974065]
GI50 0.00022Growth inhibition of human WiDr cells [AID626307, Type: Literature]
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32
[SID124974065]
IC50 0.00023Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay [AID524795, Type: Literature]
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33
[SID124974065]
IC50 0.00025Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
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34
[SID124974065]
GI50 0.00027Growth inhibition of human A2780 cells [AID626301, Type: Literature]
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35
[SID124974065]
IC50 0.00027Antiproliferative activity against human CEM cells after 48 hrs by sulforhodamine B assay [AID605769, Type: Literature]
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36
[SID124974065]
IC50 0.00027Antiproliferative activity against human CEM after 48 hrs by SRB assay [AID627404, Type: Literature]
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37
[SID124974065]
IC50 0.000287SANGER: Inhibition of human TE-15 cell growth in a cell viability assay. [AID742013, Type: other]
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38
[SID124974065]
IC50 0.0003Cytotoxicity against human TW01 cells [AID292969, Type: Literature]
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39
[SID124974065]
IC50 0.0003The compound was evaluated for the growth inhibition of Dx5 w/PSC cell lines using MTT assay. [AID63724, Type: Literature]
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40
[SID124974065]
IC50 0.00031Cytotoxicity expressed as concentration required to inhibit cell growth by 50% on continuous exposure time of 96h in PG-49 cell line by MTT assay. [AID155344, Type: Literature]
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41
[SID124974065]
IC50 0.000317SANGER: Inhibition of human LC-2-ad cell growth in a cell viability assay. [AID742313, Type: other]
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42
[SID124974065]
IC50 0.0004Antiproliferative activity against human PC3 cells after 48 hrs by SRB assay [AID697551, Type: Literature]
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43
[SID124974065]
IC50 0.0004Antiproliferative activity against mouse L1210 cells after 48 hrs by sulforhodamine B assay [AID605717, Type: Literature]
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44
[SID124974065]
IC50 0.0004Antiproliferative activity against mouse L1210 after 48 hrs by SRB assay [AID627397, Type: Literature]
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45
[SID124974065]
GI50 0.0004Anticancer activity against human Hep3B cells after 3 days by SRB assay [AID515576, Type: Literature]
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46
[SID124974065]
ED50 0.0004Cytotoxicity against human KB cells [AID399942, Type: Literature]
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47
[SID124974065]
IC50 0.00043Antiproliferative activity against human PC3 cells by sulforhodamine B assay [AID612323, Type: Literature]
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48
[SID124974065]
IC50 0.00044Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay [AID685137, Type: Literature]
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49
[SID124974065]
IC50 0.0005Inhibition of human KSP [AID339815, Type: Literature]
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50
[SID124974065]
IC50 0.0005Cytotoxicity expressed as concentration required to inhibit cell growth by 50% on continuous exposure time of 96h in MCF-7 cell line by MTT assay. [AID104059, Type: Literature]
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