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Paclitaxel (CID 36314) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2233)
 
 
Inactive(620)
 
 
Inconclusive(151)
 
 
Unspecified(1361)
 
 
Top Targets:
beta tubulin(44)
 
 
 
 
7TM GPCR Srx(36)
 
 
 
 
ABC MTABC3 MD..(34)
 
 
 
 
7TM GPCR Srsx(30)
 
 
 
 
alpha tubulin(25)
 
 
 
 
BioAssay Types:
Literature(2981)
 
 
 
 
 
Confirmatory(851)
 
 
 
 
 
Screening(334)
 
 
 
 
Summary(15)
 
 
 
 
BioActivity Types:
IC50(1846)
 
 
 
 
 
Potency(241)
 
 
 
 
 
EC50(48)
 
 
 
 
Kd(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 4152    Data Row: 4365   Total Pages: 219   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID124974065]
GI50 2.4e-06Inhibitory concentration against MBA-MB231 (breast) cells [AID103187, Type: Literature]
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2
[SID124974065]
GI50 9.2e-06Inhibitory concentration against 2008 (ovarian) cells [AID3018, Type: Literature]
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3
[SID124974065]
IC50 1e-05Cytotoxicity against human SW626 cells after 72 hrs by SRB assay [AID334868, Type: Literature]
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4
[SID124974065]
GI50 1e-05Antiproliferative activity against human MESSA cells by SRB assay [AID351328, Type: Literature]
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5
[SID124974065]
GI50 1e-05Antiproliferative activity against human A431 cells by SRB assay [AID351333, Type: Literature]
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6
[SID124974065]
ED50 1.2e-05Growth inhibition of human SW626 cells xenografted in ip dosed NCr nu/nu mouse administered once daily from day 3 to 6 after implantation measured on day 7 by MTT-based hollow-fiber test [AID422136, Type: Literature]
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7
[SID124974065]
GI50 1.5e-05Inhibitory concentration against PC3 (prostrate) cells [AID156638, Type: Literature]
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8
[SID124974065]
IC50 1.6e-05Cytotoxicity against human Hep3B2 cells after 72 hrs by MTS assay [AID617223, Type: Literature]
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9
[SID124974065]
GI50 1.7e-05Growth inhibition of human HBL100 cells [AID626302, Type: Literature]
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10
[SID124974065]
GI50 3.3e-05Growth inhibition of human HeLa cells [AID626303, Type: Literature]
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11
[SID124974065]
IC50 4e-05In vitro cytotoxic activity against uterine sarcoma (MES-SA) cells assayed by inhibition of [3H]-labeled thymidine incorporation [AID106322, Type: Literature]
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12
[SID124974065]
IC50 7e-05Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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13
[SID124974065]
IC50 9e-05Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
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14
[SID124974065]
IC50 9e-05Cytotoxicity expressed as concentration required to inhibit cell growth by 50% on continuous exposure time of 96h in L1210 cell line by MTT assay. [AID98569, Type: Literature]
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15
[SID124974065]
GI50 0.0001Growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program [AID247402, Type: Literature]
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16
[SID124974065]
ED50 0.0001Cytotoxicity against human HT-29 cells after 3 days by SRB assay [AID479073, Type: Literature]
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17
[SID124974065]
IC50 0.0001Cytotoxicity against human SKOV3 cells by MTT assay [AID663855, Type: Literature]
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18
[SID124974065]
CC50 0.0001Cytotoxicity against human KB3 cells [AID415835, Type: Literature]
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19
[SID124974065]
ED50 0.0001Anticancer activity aganist human HT-29 cells [AID592412, Type: Literature]
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20
[SID124974065]
ED50 0.0001Cytotoxicity against human HT-29 cells after 3 days by sulforhodamine B assay [AID599228, Type: Literature]
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