7-chloro-N-(4-chlorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine
(CID
3600217
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
1
)
Inactive(
1
)
Top Targets:
14-3-3 gamma(
1
)
HSPA1-2 6-8-l..(
1
)
BioAssay Types:
Screening(
1
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 2 Data Row: 2 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
152186719
]
Active
Late stage assay for the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70). Luminescence-based-cell-based high-throughput dose response assay for Hsp70 activators [AID
651950
, Type: other]
Heat shock 70kDa protein 1A [Homo sapiens] [gi:
12803275
]
View
X
Row No.
1
Structure
Substance
SID
152186719
CID
3600217
Outcome
Active
BioAssay
Late stage assay for the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70). Luminescence-based-cell-based high-throughput dose response assay for Hsp70 activators
AID
651950
BioAssay type
other
Target
Heat shock 70kDa protein 1A [Homo sapiens] [gi:
12803275
]
PubMed
Data Table
2
[SID
152186719
]
Active
Late stage assay for the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70). Luminescence-based-cell-based high-throughput dose response assay for Hsp70 activators [AID
651950
, Type: other]
Heat shock 70kDa protein 1A [Homo sapiens] [gi:
12803275
]
View
X
Row No.
2
Structure
Substance
SID
152186719
CID
3600217
Outcome
Active
BioAssay
Late stage assay for the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70). Luminescence-based-cell-based high-throughput dose response assay for Hsp70 activators
AID
651950
BioAssay type
other
Target
Heat shock 70kDa protein 1A [Homo sapiens] [gi:
12803275
]
PubMed
Data Table
3
[SID
24299694
]
Inactive
HTS for 14-3-3 protein interaction modulators [AID
422
, Type: screening]
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide [Homo sapi [gi:
21464101
]
View
X
Row No.
3
Structure
Substance
SID
24299694
CID
3600217
Outcome
Inactive
BioAssay
HTS for 14-3-3 protein interaction modulators
AID
422
BioAssay type
screening
Target
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide [Homo sapi [gi:
21464101
]
PubMed
Data Table