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BioActivity Data for Compound Hexachlorophene (CID 3598)

BioActivity Outcomes:
Active(617)
 
 
Inactive(880)
 
 
Inconclusive(365)
 
 
Unspecified(311)
 
 
Top Targets:
7tm 4(84)
 
 
 
 
NR LBD PPAR(40)
 
 
 
 
NR LBD ER(34)
 
 
 
 
 
NR LBD AR(26)
 
 
 
 
NR LBD TR(21)
 
 
 
 
BioAssay Types:
Confirmatory(925)
 
 
 
 
 
Screening(611)
 
 
 
 
Literature(135)
 
 
 
 
 
Summary(87)
 
 
 
 
BioAssay Categories:
In vitro(135)
 
 
 
 
In vivo(139)
 
 
 
 
Biochemical(291)
 
 
 
 
 
Toxicity(220)
 
 
 
 
 
ADME(23)
 
 
Cell-based(299)
 
 
 
 
 
Organism-base..(27)
 
 
 
 
BioActivity Types:
Potency(682)
 
 
 
 
 
IC50(209)
 
 
 
 
 
EC50(28)
 
 
 
 
AC50(20)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1494    Data Row: 2173   Total Pages: 109   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170464690]
IC50 0.003SW480 viability from Cell TiterGlo-IC50 [AID1117338, Type: confirmatory]
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2
[SID170464690]
IC50 0.0157DLD-1 viability from Cell TiterGlo-IC50 [AID1117352, Type: confirmatory]
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3
[SID170464690]
IC50 0.03121HCT116 viability from Cell TiterGlo-IC50 [AID1117332, Type: confirmatory]
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4
[SID170464690]
IC50 0.032SNU-C1 viability from Cell TiterGlo-IC50 [AID1117323, Type: confirmatory]
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5
[SID170464690]
IC50 0.0572Colo320 viability from Cell TiterGlo-IC50 [AID1117334, Type: confirmatory]
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6
[SID103171247]
IC50 0.0876DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein) [AID625182, Type: confirmatory]Mitogen-activated protein kinase 14 [gi:2499600]
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7
[SID170464690]
IC50 0.1085RKO viability from Cell TiterGlo-IC50 [AID1117322, Type: confirmatory]
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8
[SID144208548]
Potency-Replicate_1 0.1733qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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9
[SID103171247]
IC50 0.196DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein) [AID625181, Type: confirmatory]Mitogen-activated protein kinase 1 [gi:119554]
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10
[SID8139957]
EC50 0.202Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity [AID1902, Type: confirmatory]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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11
[SID8139957]
EC50 0.244Luminescence Microorganism-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to SK(-)GAS Group A Streptococcus [AID1900, Type: confirmatory]
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12
[SID8139957]
EC50 0.262Luminescence Microorganism-Based Dose Response HTS to Identify Compounds Cytotoxic to Streptococcus [AID1915, Type: confirmatory]
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13
[SID144213058]
Potency-Replicate_1 0.3438qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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14
[SID170464690]
IC50 0.405VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-IC50 [AID1117337, Type: confirmatory]
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15
[SID144213058]
Ratio Potency (uM) 0.432771qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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16
[SID170464690]
IC50 0.4596HT-29 viability from Cell TiterGlo-IC50 [AID1117330, Type: confirmatory]
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17
[SID144208548]
Potency-Replicate_1 0.4841qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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18
[SID103171247]
IC50 0.6389DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA) [AID625196, Type: confirmatory]Adenosine receptor A3 [gi:1351831]
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19
[SID103171247]
IC50 0.6443DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid) [AID625244, Type: confirmatory]Prostaglandin G/H synthase 2 [gi:3915797]
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20
[SID56422370]
AC50_uM 0.676Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_Dose_CherryPick_Activity [AID540268, Type: confirmatory]HSP90 [Plasmodium falciparum 3D7] [gi:124809506]
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