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BioActivity Data for Compound Haloperidol (CID 3559)

BioActivity Outcomes:
Active(925)
 
 
Inactive(1629)
 
 
Inconclusive(193)
 
 
Unspecified(2247)
 
 
Top Targets:
7tm 4(402)
 
 
 
 
 
ERG2 Sigma1R(69)
 
 
 
p450(35)
 
 
 
 
 
FAM101(27)
 
 
 
 
NR LBD PPAR(27)
 
 
 
BioAssay Types:
Literature(1787)
 
 
 
 
 
Confirmatory(1095)
 
 
 
 
 
Screening(672)
 
 
 
 
Summary(59)
 
 
 
 
BioAssay Categories:
In vitro(269)
 
 
 
 
 
In vivo(1271)
 
 
 
 
 
Biochemical(1297)
 
 
 
 
 
Toxicity(1278)
 
 
 
 
 
ADME(156)
 
 
 
 
Cell-based(458)
 
 
 
 
 
Organism-base..(21)
 
 
 
BioActivity Types:
Potency(782)
 
 
 
 
 
Ki(520)
 
 
 
 
IC50(401)
 
 
 
 
 
EC50(20)
 
 
 
 
 
AC50(12)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 4193    Data Row: 4994   Total Pages: 250   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103167216]
IC50 7.5e-05In vivo binding affinity against dopamine (D2) receptor in rat caudate-putamen tissue using [3H]nemonapride as radioligand [AID64435, Type: Literature]
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2
[SID103167216]
Ki 0.0001Ratio of Ki for human dopamine D2 receptor to Ki for human dopamine D4 receptor [AID392767, Type: Literature]
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3
[SID103167216]
Ki 0.00012Binding affinity towards human Dopamine receptor D2 using [3H]spiroperidol as radioligand [AID63061, Type: Literature]
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4
[SID103167216]
Ki 0.00016Displacement of [3H]quinpirole from Dopamine receptor D2 [AID63075, Type: Literature]
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5
[SID103167216]
Ki 0.00016Displacement of [3H]quinpirole from human dopamine D2A receptors expressed in LtK cells [AID61612, Type: Literature]D(2) dopamine receptor [gi:118206]
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6
[SID103167216]
Ki 0.0002Binding towards Dopamine receptor D2 using [3H]spiperone from rat striatal membrane [AID65560, Type: Literature]D(2) dopamine receptor [gi:47117674]
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7
[SID103167216]
Ki 0.0002Affinity for Dopamine receptor D2 [AID65243, Type: Literature]D(2) dopamine receptor [gi:47117674]
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8
[SID103167216]
Ki 0.0002Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone [AID65247, Type: Literature]
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9
[SID103167216]
Ki 0.0002Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand [AID239347, Type: Literature]
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10
[SID103167216]
Ki 0.0002Binding affinity towards dopamine receptor D2 by displacing [3H]spiperone radioligand in rat striatum [AID65908, Type: Literature]
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11
[SID103167216]
IC50 0.00028Ability to inhibit [3H]haloperidol binding to dopamine receptor in rat striatal homogenate [AID63028, Type: Literature]D(2) dopamine receptor [gi:47117674]
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12
[SID103167216]
IC50 0.00028Ability to inhibit [3H]haloperidol binding to dopamine receptor in rat striatal homogenate [AID63028, Type: Literature]D(4) dopamine receptor [gi:6226851]
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13
[SID103167216]
IC50 0.00028Ability to inhibit [3H]haloperidol binding to dopamine receptor in rat striatal homogenate [AID63028, Type: Literature]D(3) dopamine receptor [gi:118211]
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14
[SID103167216]
IC50 0.00028Ability to inhibit [3H]haloperidol binding to dopamine receptor in rat striatal homogenate [AID63028, Type: Literature]D(1A) dopamine receptor [gi:118229]
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15
[SID103167216]
IC50 0.00028Ability to inhibit [3H]haloperidol binding to dopamine receptor in rat striatal homogenate [AID63028, Type: Literature]D(1B) dopamine receptor [gi:118251]
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16
[SID103167216]
Ki 0.0003Evaluated for binding towards Dopamine receptor D2 using [3H]-spiperone as radioligand, in cloned mammalian receptors expressed in CHO-K1 cells [AID62338, Type: Literature]
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17
[SID103167216]
Ki 0.00033Tested for [3H](+)-pentazocine binding to sigma-1 receptor in guinea pig brain membrane [AID229213, Type: Literature]
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18
[SID103167216]
Ki 0.00033Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2 [AID65562, Type: Literature]D(2) dopamine receptor [gi:47117674]
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19
[SID103167216]
Ki 0.00037Binding affinity towards dopamine D2 receptors in rat brain synaptosomal preparations [AID65905, Type: Literature]D(2) dopamine receptor [gi:47117674]
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20
[SID103167216]
Ki 0.00037Compound was evaluated for its binding affinity with Dopamine receptor D2 using membranes prepared from rat striatum [AID65402, Type: Literature]
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