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Zidovudine (CID 35370) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1146)
 
 
Inactive(1555)
 
 
Inconclusive(143)
 
 
Unspecified(1845)
 
 
Top Targets:
7tm 4(88)
 
 
 
NR LBD PPAR(42)
 
 
 
NR LBD ER(37)
 
 
 
 
NR LBD AR(33)
 
 
 
 
p450(24)
 
 
 
 
BioAssay Types:
Literature(2634)
 
 
 
 
 
Confirmatory(980)
 
 
 
 
 
Screening(628)
 
 
 
 
Summary(87)
 
 
 
BioActivity Types:
Potency(707)
 
 
 
 
 
EC50(690)
 
 
 
 
 
IC50(605)
 
 
 
 
 
Ki(9)
 
 
 
 
Kd(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 4167    Data Row: 4689   Total Pages: 235   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103188975]
EC50 4e-06Antiviral activity against Human immunodeficiency virus 1 infected in human C8166 cells assessed as inhibition of virus-induced cytopathic effect [AID610675, Type: Literature]
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2
[SID103188975]
EC50 4e-06Antiviral activity against Human immunodeficiency virus 1 assessed as inhibition of virus-induced cytopathic effects by cell based assay [AID611912, Type: Literature]
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3
[SID103188975]
IC50 0.0001Antiviral activity against Human immunodeficiency virus 1 subtype O BCF03 infected in phytohemagglutininin and interleukin-2-stimulated PBMC assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay [AID576144, Type: Literature]
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4
[SID103188975]
IC50 0.0001Antiviral activity against Human immunodeficiency virus 1 subtype G JV 1083 infected in phytohemagglutininin and interleukin-2-stimulated PBMC assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay [AID576141, Type: Literature]
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5
[SID103188975]
IC50 0.00014Antiviral activity against HIV1 TEKI replication in PBMC at 1 uM [AID257926, Type: Literature]
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6
[SID103188975]
IC50 0.00018Antiviral activity against HIV1 NL4-3 replication in PBMC at 1 uM [AID257928, Type: Literature]
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7
[SID103188975]
IC50 0.0002Antiviral activity against Human immunodeficiency virus 2 CDC 310319 infected in phytohemagglutininin and interleukin-2-stimulated PBMC assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay [AID576145, Type: Literature]
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8
[SID103188975]
IC50 0.0003Antiviral activity against Human immunodeficiency virus 1 subtype F BR/93/020 infected in phytohemagglutininin and interleukin-2-stimulated PBMC assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay [AID575960, Type: Literature]
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9
[SID103188975]
IC50 0.0003Antiviral activity against of Human immunodeficiency virus 1 3B infected in AA5 cells infected with 1.56 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay [AID576379, Type: Literature]
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10
[SID103188975]
IC50 0.0003Antiviral activity against of Human immunodeficiency virus 1 3B infected in AA5 cells infected with 0.78 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay [AID576380, Type: Literature]
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11
[SID103188975]
IC50 0.0003Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 12.5 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay [AID576388, Type: Literature]
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12
[SID103188975]
IC50 0.0003Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 6.25 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay [AID576389, Type: Literature]
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13
[SID103188975]
IC50 0.0003Antiviral activity against Human immunodeficiency virus 1 3B infected in human H9 cells infected with 6.25 uL of virus stock assessed as expression of p24 antigen after 6 days postinfection by ELISA [AID576392, Type: Literature]
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14
[SID103188975]
EC50 0.00032Concentration of the drug resulting in 50% reduction of the viral cytopathic effect against HIV-1 replication in CEM cells. [AID47640, Type: Literature]
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15
[SID103188975]
IC50 0.0004Antiviral activity against of Human immunodeficiency virus 1 3B infected in AA5 cells infected with 3.13 uL of virus stock assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay [AID576200, Type: Literature]
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16
[SID103188975]
IC50 0.0005Antiviral activity against simian immunodeficiency virus 69R infected in phytohemagglutininin and interleukin-2-stimulated PBMC assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay [AID576148, Type: Literature]
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17
[SID103188975]
IC50 0.0005Antiviral activity against Human immunodeficiency virus 1 subtype O BCF02 infected in phytohemagglutininin and interleukin-2-stimulated PBMC assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay [AID576143, Type: Literature]
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18
[SID103188975]
EC50 0.00053Antiviral activity against HIV1 NL 4-3 expressing wild type reverse transcriptase infected in human PBMC by ELISA [AID548556, Type: Literature]
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19
[SID103188975]
IC50 0.0007Antiviral activity against Human immunodeficiency virus 1 subtype D UG/92/046 infected in phytohemagglutininin and interleukin-2-stimulated PBMC assessed as inhibition of viral Reverse transcriptase by [3H]TTP incorporation assay [AID575958, Type: Literature]
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20
[SID103188975]
EC50 0.0007Antiviral activity against HIV1 3B assessed as inhibition of virus-induced cytopathogenicity in MT4 cells after 4 days by MTT assay [AID322392, Type: Literature]
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