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3-cyclohexyl-6-(3,4-dimethoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine (CID 3523871) - Compound BioActivity Data
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BioActivity Outcomes:
Active(41)
 
 
Inactive(719)
 
 
Inconclusive(24)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(43)
 
 
 
alkPPc(12)
 
 
Bcl-2 like(11)
 
 
Tryp SPc(9)
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(534)
 
 
 
 
Confirmatory(222)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(151)
 
 
 
 
 
IC50(52)
 
 
 
 
EC50(12)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 713    Data Row: 785   Total Pages: 40   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14743139]
IC50 1.7378Dose responses of compounds that inhibit the Choline Transporter (CHT) - 5 point CRC [AID504840, Type: confirmatory]high affinity choline transporter 1 [Homo sapiens] [gi:11141885]
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2
[SID14743139]
Potency 2.3109qHTS Assay to Find Inhibitors of Chronic Active B-Cell Receptor Signaling: Hit Validation in Primary Screen [AID651558, Type: confirmatory]
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3
[SID14743139]
Potency 3.1623qHTS of GLP-1 Receptor Agonists [AID624172, Type: confirmatory]glp-1 receptor, partial [Homo sapiens] [gi:1724069]
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4
[SID14743139]
IC50 3.414Luminescent dose response cell-based high throughput screening assay for inhibitors of the Janus kinase 2 mutant JAK2V617F [AID1691, Type: confirmatory]
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5
[SID14743139]
Potency 4.6535Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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6
[SID14743139]
IC50 7.519Luminescent counterscreen for inhibitors of the Janus kinase 2 mutant JAK2V617F: dose response cell-based high throughput screening assay for inhibitors of parental Ba/F3 cell viability. [AID1699, Type: confirmatory]Janus kinase 2 (a protein tyrosine kinase) [Homo sapiens] [gi:119579178]
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7
[SID14743139]
Potency 8.1995qHTS of GLP-1 Receptor Agonists: Hit Validation [AID743262, Type: confirmatory]glp-1 receptor, partial [Homo sapiens] [gi:1724069]
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8
[SID14743139]
irf1 Inhibition [Ba/F3 cells] (IC50) 8.925Late stage results from the probe development effort to identify inhibitors of the Janus kinase 2 mutant JAK2V617F. [AID2165_4, Type: screening]Janus kinase 2 (a protein tyrosine kinase) [Homo sapiens] [gi:119579178]
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9
[SID14743139]
irf1 Inhibition [HEL cells] (IC50) 13.34Late stage results from the probe development effort to identify inhibitors of the Janus kinase 2 mutant JAK2V617F. [AID2165_3, Type: screening]Janus kinase 2 (a protein tyrosine kinase) [Homo sapiens] [gi:119579178]
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10
[SID14743139]
Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease [AID624483, Type: screening]
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11
[SID14743139]
Late stage results from the probe development effort to identify inhibitors of the Janus kinase 2 mutant JAK2V617F. [AID2165, Type: screening]Janus kinase 2 (a protein tyrosine kinase) [Homo sapiens] [gi:119579178]
View
12
[SID14743139]
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F [AID1446, Type: screening]Janus kinase 2 (a protein tyrosine kinase) [Homo sapiens] [gi:119579178]
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13
[SID14743139]
Confirmation cell-based high throughput screening assay for inhibitors of the Janus kinase 2 mutant JAK2V617F [AID1521, Type: screening]Janus kinase 2 (a protein tyrosine kinase) [Homo sapiens] [gi:119579178]
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14
[SID14743139]
Primary cell-based screen for identification of compounds that inhibit the Choline Transporter (CHT) [AID488975, Type: screening]high affinity choline transporter 1 [Homo sapiens] [gi:11141885]
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15
[SID14743139]
Confirmatory screen for compounds that inhibit the Choline Transporter (CHT) [AID493221, Type: screening]high affinity choline transporter 1 [Homo sapiens] [gi:11141885]
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16
[SID14743139]
CYP2C9 Assay [AID777, Type: screening]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
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17
[SID14743139]
Modulators of the EP2 prostaglandin E2 receptor - Primary Screening [AID940, Type: screening]prostaglandin E2 receptor EP2 subtype [Homo sapiens] [gi:31881630]
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18
[SID14743139]
Modulators of the EP2 prostaglandin EP2 receptor - Primary Counterscreens [AID1080, Type: other]prostaglandin E2 receptor EP2 subtype [Homo sapiens] [gi:31881630]
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19
[SID14743139]
Counterscreen for activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM): Luminescence-based cell-based high throughput screening assay to identify non-selective compounds using the VP16 reporter assay [AID686939, Type: screening]
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20
[SID14743139]
CYP2C19 Assay [AID778, Type: screening]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
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