Bookmark and Share
F1301-0108 (CID 3505101) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(12)
 
 
Inactive(669)
 
 
Inconclusive(16)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
 
7TM GPCR Srsx(20)
 
 
Firefly Luc l..(11)
 
 
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
BioAssay Types:
Screening(465)
 
 
 
 
Confirmatory(211)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(158)
 
 
 
 
 
IC50(39)
 
 
EC50(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 639    Data Row: 699   Total Pages: 14   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17515161]
Potency 7.3003FLuc inhibitory activity for the follow-up compounds in a biochemical assay with Km concentrations of substrate and 500microM CoASH [AID602358, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
2
[SID17515161]
Potency 12.6483FLuc inhibitory activity for the follow-up compounds in a cell-based assay to assess the activity of miR-21 [AID602477, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
3
[SID17515161]
Potency 16.9441qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
4
[SID17515161]
Potency 18.3375FLuc inhibitory activity for the follow-up compounds in a biochemical assay with Km concentrations of substrate [AID602357, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
5
[SID17515161]
Potency 19.9526qHTS of TDP-43 Inhibitors [AID652104, Type: confirmatory]TAR DNA-binding protein 43 [gi:20140568]
View
6
[SID17515161]
Potency 25.9024FLuc inhibitory activity for the follow-up compounds in a biochemical assay with 1mM ATP [AID602364, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
7
[SID17515161]
FRET-based cell-based primary high throughput screening assay to identify antagonists of the orexin 1 receptor (OX1R; HCRTR1) [AID485270, Type: screening]orexin receptor type 1 [Homo sapiens] [gi:222080095]
View
8
[SID17515161]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
View
9
[SID17515161]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
View
10
[SID17515161]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
View
11
[SID17515161]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
View
12
[SID17515161]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators [AID1814, Type: screening]
View
13
[SID17515161]
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
View
14
[SID17515161]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
15
[SID17515161]
Potency 5.2213Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
View
16
[SID17515161]
Potency 13.1154Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
View
17
[SID17515161]
Potency 18.4927qHTS Assay for Modulators of miRNAs and/orActivators of miR-21 [AID2288, Type: confirmatory]
View
18
[SID17515161]
uHTS identification of small molecules that induce b-cell replication in the MIN-6 cell line [AID2380, Type: screening]
View
19
[SID17515161]
IC50 A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) [AID2391, Type: confirmatory]
View
20
[SID17515161]
Inhibitors of Prion Protein 5' UTR mRNA Measured in Cell-Based System Using Plate Reader - 2078-01_Inhibitor_SinglePoint_HTS_Activity [AID488862, Type: screening]
View
21
[SID17515161]
IC50 Elucidation of physiology of non-replicating, drug-tolerant Mycobacterium tuberculosis [AID488890, Type: confirmatory]
View
22
[SID17515161]
IC50 Primary and Confirmatory Screening for Inhibitors of Bacterial Capsule Biogenesis [AID488966, Type: confirmatory]
View
23
[SID17515161]
Potency qHTS Assay to Find Inhibitors of Chronic Active B-Cell Receptor Signaling [AID493014, Type: confirmatory]
View
24
[SID17515161]
Heat Shock Factor-1 (HSF-1) Measured in Cell-Based System Using Plate Reader - 2038-01_Activator_SinglePoint_HTS_Activity [AID504408, Type: screening]
View
25
[SID17515161]
Potency Nrf2 qHTS screen for inhibitors: counterscreen for cytotoxicity [AID504648, Type: confirmatory]
View
26
[SID17515161]
Potency FLuc inhibitory activity for the follow-up compounds in a cell-based translational read-through assay (72 hour incubation) [AID602478, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
27
[SID17515161]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype [AID758, Type: screening]GTP-binding protein (rab7) [Canis lupus familiaris] [gi:164058]
View
28
[SID17515161]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ CIT2_MLPCN. [AID2029, Type: screening]citrate synthase 2, partial [Saccharomyces cerevisiae] [gi:171229]
View
29
[SID17515161]
Potency Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS [AID504937, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
30
[SID17515161]
Factor XIa 1536 HTS [AID798, Type: screening]coagulation factor XI [Homo sapiens] [gi:180352]
View
31
[SID17515161]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID759, Type: screening]ras protein, partial [Homo sapiens] [gi:190938]
View
32
[SID17515161]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
View
33
[SID17515161]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
View
34
[SID17515161]
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-2. [AID950, Type: screening]Apoptosis regulator Bcl-2 [gi:231632]
View
35
[SID17515161]
Primary screen for compounds that activate Alzheimer's amyloid precursor [AID1276, Type: screening]amyloid precursor protein [Homo sapiens] [gi:257380]
View
36
[SID17515161]
Primary screen for compounds that inhibit Alzheimer's amyloid precursor protein (APP) translation [AID1285, Type: screening]amyloid precursor protein [Homo sapiens] [gi:257380]
View
37
[SID99297123]
A screen for compounds that inhibit processive DNA synthesis of vaccinia virus [AID493162, Type: other]DNA polymerase [Vaccinia virus] [gi:335756]
View
38
[SID17515161]
Thrombin 1536 HTS [AID1046, Type: screening]prothrombin [Homo sapiens] [gi:339641]
View
39
[SID17515161]
Potency qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
View
40
[SID17515161]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ LAP4_MLPCN. [AID2023, Type: screening]LAP4 [Saccharomyces cerevisiae] [gi:486173]
View
41
[SID17515161]
Primary cell-based high-throughput screening assay for identification of compounds that protect hERG from block by proarrhythmic agents [AID1511, Type: screening]putative potassium channel subunit [Homo sapiens] [gi:487738]
View
42
[SID17515161]
Potency qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease [AID2101, Type: confirmatory]glucocerebrosidase [Homo sapiens] [gi:496369]
View
43
[SID17515161]
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL). [AID2129, Type: screening]bcl-xL [Homo sapiens] [gi:510901]
View
44
[SID17515161]
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-XL. [AID1007, Type: screening]bcl-xL [Homo sapiens] [gi:510901]
View
45
[SID17515161]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ RPL19A_MLPCN. [AID2025, Type: screening]RPL19A [Saccharomyces cerevisiae] [gi:536029]
View
46
[SID17515161]
Potency Activators of T cell receptors: qHTS campaign [AID504894, Type: confirmatory]T cell receptor [Homo sapiens] [gi:553160]
View
47
[SID17515161]
Potency qHTS of alpha-syn Inhibitors [AID652106, Type: confirmatory]Alpha-synuclein [gi:586067]
View
48
[SID17515161]
Potency qHTS of Nrf2 Activators [AID624171, Type: confirmatory]Nrf2 [Homo sapiens] [gi:693842]
View
49
[SID17515161]
Potency qHTS Assay for Inhibitors and Activators of Human alpha-Galactosidase From Spleen Homogenate [AID2107, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
View
50
[SID17515161]
Potency qHTS Assay for Inhibitors of Human alpha-Galactosidase at pH 4.5. [AID1467, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
View