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BioActivity Data for Compound 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide (CID 3499)

BioActivity Outcomes:
Active(1)
 
 
Inactive(34)
 
 
Inconclusive(3)
 
 
Unspecified(518)
 
 
Top Targets:
CYCLIN(24)
 
 
PTKc EphR A(10)
 
 
PKc like(8)
 
 
PTKc EphR B(8)
 
 
CBS pair 28(8)
 
 
BioAssay Types:
Literature(520)
 
 
 
Confirmatory(29)
 
 
 
 
Screening(5)
 
 
BioActivity Types:
Potency(29)
 
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 502    Data Row: 556   Total Pages: 28   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26756888]
Potency 7.0795qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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2
[SID103568539]
Millipore: Percentage of residual kinase activity of GRK5 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA [AID720175, Type: Literature]G protein-coupled receptor kinase 5 [gi:462203]
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3
[SID103568539]
Millipore: Percentage of residual kinase activity of GRK5 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA [AID720176, Type: Literature]G protein-coupled receptor kinase 5 [gi:462203]
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4
[SID103568539]
Millipore: Percentage of residual kinase activity of PRKCG at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 mM CaCl2, 0.1 mg/mL phosphatidylserine, 10 ug/mL diacylglycerol [AID720478, Type: Literature]Protein kinase C gamma type [gi:462455]
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5
[SID103568539]
Millipore: Percentage of residual kinase activity of PRKCG at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 20 mM HEPES pH 7.4, 0.03% Triton X-100, 0.1 mM CaCl2, 0.1 mg/mL phosphatidylserine, 10 ug/mL diacylglycerol [AID720479, Type: Literature]Protein kinase C gamma type [gi:462455]
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6
[SID103568539]
Millipore: Percentage of residual kinase activity of FLT3 at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA [AID720165, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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7
[SID103568539]
Millipore: Percentage of residual kinase activity of FLT3 at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA [AID720166, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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8
[SID103568539]
Millipore: Percentage of residual kinase activity of TEC at 1uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 1 mM Na3VO4, 5 mM Na-?-glycerophosphate [AID720398, Type: Literature]Tyrosine-protein kinase Tec [gi:158518392]
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9
[SID103568539]
Millipore: Percentage of residual kinase activity of TEC at 10uM relative to control. Control inhibitor: Staurosporine at 100.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 1 mM Na3VO4, 5 mM Na-?-glycerophosphate [AID720399, Type: Literature]Tyrosine-protein kinase Tec [gi:158518392]
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10
[SID103568539]
Millipore: Percentage of residual kinase activity of BLK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol [AID720047, Type: Literature]Tyrosine-protein kinase Blk [gi:158936749]
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11
[SID103568539]
Millipore: Percentage of residual kinase activity of BLK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1 mM Na3VO4, 0.1% ?-mercaptoethanol [AID720048, Type: Literature]Tyrosine-protein kinase Blk [gi:158936749]
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12
[SID103568539]
Millipore: Percentage of residual kinase activity of MERTK at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl [AID720378, Type: Literature]Tyrosine-protein kinase Mer [gi:160332297]
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13
[SID103568539]
Millipore: Percentage of residual kinase activity of MERTK at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl [AID720379, Type: Literature]Tyrosine-protein kinase Mer [gi:160332297]
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14
[SID103568539]
Millipore: Percentage of residual kinase activity of CDK9 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA [AID720071, Type: Literature]Cyclin-dependent kinase 9 [gi:68067660]
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15
[SID103568539]
Millipore: Percentage of residual kinase activity of CDK9 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA [AID720072, Type: Literature]Cyclin-dependent kinase 9 [gi:68067660]
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16
[SID103568539]
Millipore: Percentage of residual kinase activity of PRKCZ at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA [AID720199, Type: Literature]Protein kinase C zeta type [gi:68067736]
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17
[SID103568539]
Millipore: Percentage of residual kinase activity of PRKCZ at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA [AID720484, Type: Literature]Protein kinase C zeta type [gi:68067736]
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18
[SID103568539]
Millipore: Percentage of residual kinase activity of CDC42BPA at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA [AID720362, Type: Literature]Serine/threonine-protein kinase MRCK alpha [gi:74746874]
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19
[SID103568539]
Millipore: Percentage of residual kinase activity of CDC42BPA at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA [AID720363, Type: Literature]Serine/threonine-protein kinase MRCK alpha [gi:74746874]
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20
[SID103568539]
Millipore: Percentage of residual kinase activity of TAOK1 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA, 50 mM NaCl [AID720286, Type: Literature]Serine/threonine-protein kinase TAO1 [gi:74759012]
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