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6-iodo-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid (CID 3439114) - Compound BioActivity Data
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BioActivity Outcomes:
Active(9)
 
 
Inactive(12)
 
 
Top Targets:
DSPc(3)
 
 
PTPc(2)
 
 
 
HSPA1-2 6-8-l..(2)
 
 
crotonase-lik..(1)
 
 
Gp dh C(1)
 
 
BioAssay Types:
Confirmatory(9)
 
 
 
Screening(2)
 
 
 
Literature(2)
 
 
BioActivity Types:
IC50(9)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 20    Data Row: 21   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26513890]
IC50 3.13In Vitro Hsp70 Dose Response Fluorescence Polarization Assay for SAR Study [AID1072, Type: confirmatory]heat shock 70kDa protein 1A [Homo sapiens] [gi:123271505]
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2
[SID26513890]
IC50 14.1In Vitro Hsc70 Dose Response Fluorescence Polarization Assay [AID1193, Type: confirmatory]heat shock cognate 71 kDa protein isoform 2 [Homo sapiens] [gi:24234686]
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3
[SID26513890]
IC50 14.1In Vitro Hsc70 Dose Response Fluorescence Polarization Assay [AID1193, Type: confirmatory]heat shock cognate 71 kDa protein isoform 1 [Homo sapiens] [gi:5729877]
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4
[SID26513890]
IC50 47.8GAPDH Dose Response Colorimetric Assay [AID1227, Type: confirmatory]glyceraldehyde-3-phosphate dehydrogenase isoform 1 [Homo sapiens] [gi:7669492]
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5
[SID26513890]
IC50 71.4In Vitro HePTP Dose Response Colorimetric Assay for SAR Study [AID1059, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
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6
[SID92167755]
A screen for compounds that inhibit the bacterial siderophore biosynthetic enzyme BasE [AID485350, Type: screening]enterobactin synthase subunit E [Acinetobacter baumannii ATCC 17978] [gi:126642418]
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7
[SID92167755]
A screen for compounds that inhibit the CapD enzyme of Bacillus anthracis [AID492967, Type: other]gamma-glutamyltranspeptidase [Bacillus anthracis str. 'Ames Ancestor'] [gi:47566732]
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8
[SID92167755]
A screen for compounds that inhibit the bacterial siderophore biosynthetic enzyme MbtI [AID493033, Type: other]Isochorismate synthase/isochorismate lyase [gi:81706979]
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9
[SID92167755]
A screen for compounds that modulate the activity of the Staphylococcus aureus MgrA protein [AID602314, Type: other]MarR family regulatory protein [Staphylococcus aureus subsp. aureus str. Newman] [gi:151220867]
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10
[SID26513890]
IC50_Mean 100Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP [AID1077, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
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11
[SID26513890]
IC50 100MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors [AID1052, Type: confirmatory]dual specificity protein phosphatase 6 [Rattus norvegicus] [gi:16758752]
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12
[SID26513890]
IC50_Mean 100MKP-3 in vitro secondary assay for identification of redox-state modulating compounds [AID1054, Type: confirmatory]dual specificity protein phosphatase 6 [Rattus norvegicus] [gi:16758752]
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13
[SID26513890]
IC50_Mean 100In Vitro MKP-3 Dose Response Assay for SAR Study [AID1055, Type: confirmatory]dual specificity protein phosphatase 6 [Rattus norvegicus] [gi:16758752]
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14
[SID92167755]
A screen for compounds that inhibit nucleocapsid/RNA interactions in Rift Valley Fever Virus [AID651828, Type: other]Nucleoprotein [gi:127925]
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15
[SID92167755]
Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection [AID720717, Type: other]ORF 73 [Human herpesvirus 8 type M] [gi:1718329]
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16
[SID92167755]
A screen for compounds that inhibit replication of Vibrio cholerae chromosome II [AID504770, Type: other]hypothetical protein VC_A0002 [Vibrio cholerae O1 biovar El Tor str. N16961] [gi:9657380]
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17
[SID92167755]
A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis [AID540299, Type: Literature]Naphthoate synthase MenB (dihydroxynaphthoic acid synthetase) (DHNA synthetase) [Mycobacterium tuberculosis H37Rv] [gi:15607688]
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18
[SID92167755]
A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus [AID720641, Type: other]anion-binding protein [Staphylococcus aureus subsp. aureus Mu50] [gi:15923709]
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19
[SID8053269]
HIV-1 RNase H Inhibition [AID372, Type: screening]Chain A, Solution Structure Of The Rnase H Domain Of The Hiv-1 Reverse Transcriptase In The Presence Of Magnesium [gi:28949057]
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20
[SID92167755]
A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities [AID588519, Type: Literature]Chain A, Poliovirus Polymerase With Gtp [gi:52695378]
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