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Sodium Dodecyl Sulfate (CID 3423265) - Compound BioActivity Data
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BioActivity Outcomes:
Active(20)
 
 
Inactive(606)
 
 
Inconclusive(97)
 
 
Unspecified(68)
 
 
Top Targets:
NR LBD PPAR(39)
 
 
 
 
NR LBD AR(27)
 
 
 
NR LBD ER(27)
 
 
 
NR LBD TR(21)
 
 
 
 
NR LBD VDR(19)
 
 
 
 
BioAssay Types:
Confirmatory(554)
 
 
 
 
Literature(136)
 
 
 
 
 
Summary(72)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(531)
 
 
 
 
Ki(1)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 339    Data Row: 791   Total Pages: 16   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103191634]
IC50 0.000222Cytotoxicity against human HepG2/C3A cells after 24 hrs by neutral red uptake assay [AID637044, Type: Literature]
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2
[SID103191634]
Ki 2Displacement of C18-Aib-lucifer yellow from HIV1 envelope glycoprotein gp41 Fe(env2.0)3 receptor by fluorescence assay [AID421183, Type: Literature]
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3
[SID144210469]
TR Potency (uM) 15.3553qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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4
[SID144210469]
Potency-Replicate_1 24.5412qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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5
[SID144210469]
Ratio Potency (uM) 29.7324qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway: Summary [AID743241, Type: summary]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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6
[SID144210469]
Potency-Replicate_1 34.6654qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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7
[SID144208812]
Potency-Replicate_1 38.3391qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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8
[SID144210469]
Potency-Replicate_1 38.8952qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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9
[SID26752879]
Potency 44.6684Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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10
[SID144208812]
Ratio Potency (uM) 52.1165qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743227, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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11
[SID144208812]
Potency-Replicate_1 53.7079qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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12
[SID144210469]
Ratio Potency (uM) 57.0904qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743227, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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13
[SID144208812]
Potency-Replicate_1 60.2613qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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14
[SID26752879]
Potency 79.4328Inhibitors of USP1/UAF1: Pilot qHTS [AID504865, Type: confirmatory]USP1 protein [Homo sapiens] [gi:118600387]
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15
[SID144208812]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743199, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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16
[SID103191634]
Effect on morphological changes in reconstituted human epidermis model assessed as induction of tissue degeneration and necrosis after 24 hrs [AID404163, Type: Literature]
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17
[SID103191634]
Effect on modulation in uptake of [3H]progesterone in Escherichia coli AG102 with marR1 mutation [AID283561, Type: Literature]
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18
[SID103191634]
Effect on modulation in uptake of [3H]hydrocortisone in Escherichia coli AG102 with marR1 mutation [AID283562, Type: Literature]
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19
[SID103191634]
Effect on modulation in uptake of [3H]testosterone in Escherichia coli AG102 with marR1 mutation [AID283563, Type: Literature]
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20
[SID144208812]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743239, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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21
[SID103191634]
MIC 250Antibacterial activity against 5 x 10'5 CFU/mL Staphylococcus aureus subsp. aureus ATCC 29213 after 72 hrs by CLSI M07-A8 broth microdilution method [AID613554, Type: Literature]
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22
[SID103191634]
MIC 500Antibacterial activity against 5 x 10'5 CFU/mL Pseudomonas aeruginosa Boston 41501 ATCC 27853 after 72 hrs by CLSI M07-A8 broth microdilution method [AID613551, Type: Literature]
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23
[SID103191634]
MIC 500Antibacterial activity against 5 x 10'5 CFU/mL Escherichia coli ATCC 25922 after 72 hrs by CLSI M07-A8 broth microdilution method [AID613552, Type: Literature]
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24
[SID103191634]
MIC 500Antibacterial activity against 5 x 10'5 CFU/mL Enterococcus faecalis ATCC 29212 after 72 hrs by CLSI M07-A8 broth microdilution method [AID613553, Type: Literature]
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25
[SID103191634]
Antibacterial activity against 5 x 10'5 CFU/mL Enterococcus faecalis ATCC 29212 incubated for 72 hrs followed by growing of cells on trypticase soy agar plate for 24 hrs by CLSI M07-A8 broth microdilution method [AID613556, Type: Literature]
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26
[SID103191634]
Antibacterial activity against 5 x 10'5 CFU/mL Staphylococcus aureus subsp. aureus ATCC 29213 incubated for 72 hrs followed by growing of cells on trypticase soy agar plate for 24 hrs by CLSI M07-A8 broth microdilution method [AID613558, Type: Literature]
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27
[SID103191634]
Antibacterial activity against 5 x 10'5 CFU/mL Escherichia coli ATCC 25922 incubated for 72 hrs followed by growing of cells on trypticase soy agar plate for 24 hrs by CLSI M07-A8 broth microdilution method [AID613559, Type: Literature]
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28
[SID103191634]
Antibacterial activity against 5 x 10'5 CFU/mL Pseudomonas aeruginosa Boston 41501 ATCC 27853 incubated for 72 hrs followed by growing of cells on trypticase soy agar plate for 24 hrs by CLSI M07-A8 broth microdilution method [AID613560, Type: Literature]
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29
[SID103191634]
Percent Hemolysis observed in rat red blood cells when Treated with 1 mM concentration [AID181149, Type: Literature]
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30
[SID103191634]
Percent Hemolysis observed in rat red blood cells when Treated with 2 mM concentration [AID181150, Type: Literature]
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31
[SID103191634]
Percent Hemolysis observed in rat red blood cells when Treated with 5 mM concentration [AID181151, Type: Literature]
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32
[SID103191634]
MIC Antibacterial activity against Escherichia coli AG102 with marR1 mutation after 24 hrs [AID283558, Type: Literature]
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33
[SID103191634]
MIC Antibacterial activity against Escherichia coli AG102MB after 24 hrs [AID283559, Type: Literature]
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34
[SID103191634]
MIC Antibacterial activity against Escherichia coli HNCE4 after 24 hrs [AID283560, Type: Literature]
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35
[SID17388729]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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36
[SID17388731]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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37
[SID144204610]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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38
[SID103191634]
Toxicity assessed as induction of haemolysis in rat erythrocytes at 50 mM after 30 mins [AID288195, Type: Literature]
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39
[SID103191634]
Toxicity assessed as induction of haemolysis in rat erythrocytes at 200 mM after 30 mins [AID288196, Type: Literature]
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40
[SID103191634]
Toxicity assessed as induction of haemolysis in rat erythrocytes at 1000 mM after 30 mins [AID288197, Type: Literature]
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41
[SID103191634]
Antimicrobial activity against multidrug-resistant Escherichia coli C316 pHPA containing mutated GyrA gene by agar dilution method [AID368418, Type: Literature]
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42
[SID103191634]
Antimicrobial activity against Escherichia coli KAM32 expressing deltaacrB ydhE hsd gene by agar dilution method [AID368419, Type: Literature]
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43
[SID103191634]
Antimicrobial activity against Escherichia coli KAM32 pHPA containing mutated GyrA gene by agar dilution method [AID368420, Type: Literature]
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44
[SID103191634]
Antimicrobial activity against Escherichia coli KAM32 pSTV28 containing chloramphenicol-resistant vector by agar dilution method [AID368421, Type: Literature]
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45
[SID103191634]
Antimicrobial activity against Escherichia coli KAM32 pSTVqepA containing qepA gene ligated to pSTV28 plasmid by agar dilution method [AID368422, Type: Literature]
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46
[SID103191634]
Antimicrobial activity against Escherichia coli KAM32 pSTVdeltaqepA containing disrupted qepA gene by agar dilution method [AID368423, Type: Literature]
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47
[SID103191634]
Ratio of MIC for Escherichia coli KAM32 pSTVqepA mutant to MIC for Escherichia coli KAM32 pSTV28 mutant [AID368424, Type: Literature]
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48
[SID103191634]
Antibacterial activity against drug-resistant Enterobacter cloacae EcDC64 isolate expressing AcrAB-TolC efflux pump by broth microdilution method [AID396042, Type: Literature]
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49
[SID103191634]
Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate by broth microdilution method [AID396280, Type: Literature]
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50
[SID103191634]
Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pBGS18 plasmid by broth microdilution method [AID396281, Type: Literature]
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