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1-(2,5-dimethyl-1-phenylpyrrol-3-yl)-2-(2-nitropyridin-3-yl)oxyethanone (CID 3421797) - Compound BioActivity Data
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BioActivity Outcomes:
Active(34)
 
 
Inactive(677)
 
 
Inconclusive(20)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(44)
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
G-alpha(8)
 
 
 
DUF3371(7)
 
 
 
BioAssay Types:
Screening(492)
 
 
 
 
 
Confirmatory(217)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(151)
 
 
 
 
 
IC50(41)
 
 
 
AC50(10)
 
 
 
EC50(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 667    Data Row: 733   Total Pages: 37   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID22403484]
IC50 0.29984Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3):Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) [AID624395, Type: confirmatory]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
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2
[SID22403484]
Potency 0.3654qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation. [AID588397, Type: confirmatory]
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3
[SID22403484]
IC50 0.51715Luminescence-based cell-based high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID624394, Type: confirmatory]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
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4
[SID22403484]
AC50_uM 1.484MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_DoseNoFile_CherryPick_Activity_Set3 [AID493073, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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5
[SID22403484]
AC50_uM 1.484MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_DoseNoFile_CherryPick_Activity_Set4 [AID493102, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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6
[SID22403484]
AC50_uM 1.484MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_DoseNoFile_CherryPick_Activity_Set2 [AID493177, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
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7
[SID22403484]
Potency 2.6855qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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8
[SID22403484]
Potency 2.9093Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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9
[SID22403484]
Potency 4.6109qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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10
[SID22403484]
Potency 19.9526qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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11
[SID22403484]
Potency 20.5962qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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12
[SID22403484]
AC50_uM 34.8Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Based System Using Plate Reader - 2134-01_Inhibitor_Dose_CherryPick_Activity [AID624132, Type: confirmatory]
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13
[SID22403484]
Luminescence-based cell-based high throughput confirmation assay to identify inhibitors of the Steroid Receptor Coactivator 2 (SRC2; NCOA2) [AID652008, Type: screening]nuclear receptor coactivator 2 [Homo sapiens] [gi:5729858]
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14
[SID22403484]
Small Molecules that selectively kill Giardia lamblia: qHTS [AID540267, Type: screening]
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15
[SID22403484]
A yeast HTS for caloric restriction mimetics that inhibit age-related superoxide [AID2690, Type: screening]
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16
[SID22403484]
Inhibitors of Prion Protein 5' UTR mRNA Measured in Cell-Based System Using Plate Reader - 2078-01_Inhibitor_SinglePoint_HTS_Activity [AID488862, Type: screening]
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17
[SID22403484]
HTS for small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress [AID2732, Type: screening]DNA damage-inducible transcript 3 protein [Mus musculus] [gi:160707929]
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18
[SID22403484]
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1) [AID588354, Type: screening]nuclear receptor coactivator 1 isoform 1 [Homo sapiens] [gi:22538455]
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19
[SID22403484]
Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Based System Using Plate Reader - 2134-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID588674, Type: screening]
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20
[SID22403484]
HTS Assay for Peg3 Promoter Inhibitors [AID588405, Type: screening]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
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