T0511-2485 (CID 3409332) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(9)
 
 
Inactive(577)
 
 
Inconclusive(18)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(16)
 
 
7TM GPCR Srsx(11)
 
 
Bcl-2 like(10)
 
 
alkPPc(10)
 
 
G-alpha(6)
 
 
 
BioAssay Types:
Screening(404)
 
 
 
 
 
Confirmatory(186)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(132)
 
 
 
 
 
IC50(39)
 
 
 
EC50(10)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 606    Data Row: 606   Total Pages: 13   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID87225726]
EC50 0.761SAR analysis of selective Agonists of GPR55 using an Image-Based Assay [AID2347, Type: confirmatory]G-protein coupled receptor 55 [Homo sapiens] [gi:33695107]
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2
[SID22411139]
EC50 0.960599Image-based HTS for Selective Agonists of GPR55 [AID1961, Type: confirmatory]G-protein coupled receptor 55 [Homo sapiens] [gi:33695107]
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3
[SID22411139]
Potency 12.5893Confirmation screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504848, Type: confirmatory]
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4
[SID22411139]
Potency 12.5893Confirmation screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504850, Type: confirmatory]
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5
[SID22411139]
Potency 13.1154Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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6
[SID22411139]
Potency 20.5962qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID22411139]
Potency 20.5962qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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8
[SID22411139]
Potency 20.5962qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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9
[SID22411139]
 Leishmania major promastigote HTS [AID1063, Type: screening]
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10
[SID22411139]
 uHTS Identification of Diaphorase Inhibitors and Chemcical Oxidizers: Counter Screen for Diaphorase-based Primary Assays [AID1217, Type: screening]Dihydrolipoamide dehydrogenase [Homo sapiens] [gi:17391426]
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11
[SID22411139]
 DENV2 CPE-Based HTS Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2149-01_Other_SinglePoint_HTS_Activity [AID651640, Type: screening]
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12
[SID22411139]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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13
[SID22411139]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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14
[SID22411139]
 Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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15
[SID22411139]
 Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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16
[SID22411139]
 Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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17
[SID87225726]
IC50 32SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay [AID2338, Type: confirmatory]G-protein coupled receptor 35 isoform a [Homo sapiens] [gi:33695097]
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18
[SID87225726]
IC50 32SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay [AID2338, Type: confirmatory]G-protein coupled receptor 35 isoform a [Homo sapiens] [gi:33695097]
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19
[SID87225726]
IC50 32SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay [AID2338, Type: confirmatory]G-protein coupled receptor 35 isoform a [Homo sapiens] [gi:33695097]
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20
[SID87225726]
IC50 32SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay [AID2340, Type: confirmatory]G-protein coupled receptor 35 isoform a [Homo sapiens] [gi:33695097]
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21
[SID87225726]
IC50 32SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay [AID2340, Type: confirmatory]G-protein coupled receptor 35 isoform a [Homo sapiens] [gi:33695097]
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22
[SID87225726]
IC50 32SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay [AID2340, Type: confirmatory]G-protein coupled receptor 35 isoform a [Homo sapiens] [gi:33695097]
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23
[SID87225726]
IC50 32SAR analysis of agonists of the Cannabinoid Receptor 1 using an Image-Based Assay [AID2341, Type: confirmatory]Cannabinoid receptor 1 (brain) [Homo sapiens] [gi:71682703]
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24
[SID87225726]
IC50 32SAR analysis of agonists of the Cannabinoid Receptor 1 using an Image-Based Assay [AID2341, Type: confirmatory]Cannabinoid receptor 1 (brain) [Homo sapiens] [gi:71682703]
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25
[SID87225726]
IC50 32SAR analysis of agonists of the Cannabinoid Receptor 1 using an Image-Based Assay [AID2341, Type: confirmatory]Cannabinoid receptor 1 (brain) [Homo sapiens] [gi:71682703]
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26
[SID87225726]
IC50 32SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay [AID2339, Type: confirmatory]Cannabinoid receptor 1 (brain) [Homo sapiens] [gi:71682703]
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27
[SID87225726]
IC50 32SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay [AID2339, Type: confirmatory]Cannabinoid receptor 1 (brain) [Homo sapiens] [gi:71682703]
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28
[SID87225726]
IC50 32SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay [AID2339, Type: confirmatory]Cannabinoid receptor 1 (brain) [Homo sapiens] [gi:71682703]
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29
[SID87225726]
IC50 32SAR analysis of antagonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 [AID434922, Type: confirmatory]cannabinoid receptor 2 [Homo sapiens] [gi:4502929]
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30
[SID87225726]
IC50 32SAR analysis of antagonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 [AID434922, Type: confirmatory]cannabinoid receptor 2 [Homo sapiens] [gi:4502929]
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31
[SID87225726]
IC50 32SAR analysis of antagonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 [AID434922, Type: confirmatory]cannabinoid receptor 2 [Homo sapiens] [gi:4502929]
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32
[SID87225726]
EC50 32SAR analysis of agonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 [AID434928, Type: confirmatory]cannabinoid receptor 2 [Homo sapiens] [gi:4502929]
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33
[SID87225726]
EC50 32SAR analysis of agonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 [AID434928, Type: confirmatory]cannabinoid receptor 2 [Homo sapiens] [gi:4502929]
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34
[SID87225726]
EC50 32SAR analysis of agonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 [AID434928, Type: confirmatory]cannabinoid receptor 2 [Homo sapiens] [gi:4502929]
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35
[SID22411139]
Potency 35.4813qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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36
[SID22411139]
Potency 35.4813qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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37
[SID22411139]
Potency 89.1251qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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38
[SID22411139]
Potency 89.1251qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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39
[SID22411139]
 HTS for small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress [AID2732, Type: screening]Ddit3 gene product [Mus musculus] [gi:160707929]
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40
[SID22411139]
 uHTS for Small Molecule Inhibitors of Eukaryotic Translation Initiation [AID782, Type: screening]eukaryotic translation initiation factor 4E [Mus musculus] [gi:83627717]
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41
[SID22411139]
 uHTS for Small Molecule Inhibitors of Eukaryotic Translation Initiation [AID782, Type: screening]eukaryotic translation initiation factor 4E [Mus musculus] [gi:83627717]
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42
[SID22411139]
 Activator for delta FosB/delta FosB homodimer Measured in Biochemical System Using Plate Reader - 2072-01_Activator_SinglePoint_HTS_Activity [AID493131, Type: screening]protein fosB [Mus musculus] [gi:6679827]
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43
[SID22411139]
 uHTS identification of Gli-Sufu Antagonists in a luminescence reporter assay [AID588413, Type: screening]Gli1 [Mus musculus] [gi:6009644]
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44
[SID22411139]
 uHTS identification of Gli-Sufu Antagonists in a luminescence reporter assay [AID588413, Type: screening]Gli1 [Mus musculus] [gi:6009644]
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45
[SID22411139]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1). [AID2098, Type: screening]Hsf1 protein [Mus musculus] [gi:62740231]
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46
[SID22411139]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1). [AID2098, Type: screening]Hsf1 protein [Mus musculus] [gi:62740231]
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47
[SID22411139]
 Luminescence-based cell-based primary high throughput screening assay to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) [AID624169, Type: screening]Htr2a gene product [Mus musculus] [gi:27753985]
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48
[SID22411139]
 Luminescence-based cell-based primary high throughput screening assay to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) [AID624169, Type: screening]Htr2a gene product [Mus musculus] [gi:27753985]
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49
[SID22411139]
Potency qHTS of IL-2 Activators [AID652025, Type: confirmatory]Il2 gene product [Mus musculus] [gi:7110653]
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50
[SID22411139]
 HTS for developing T Cell Immune Modulators [AID2052, Type: screening]integrin alpha-L [Mus musculus] [gi:124486680]
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