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BioActivity Data for Compound Ethylene Chlorohydrin (CID 34)

BioActivity Outcomes:
Active(2)
 
 
Inactive(97)
 
 
Inconclusive(3)
 
 
Unspecified(2)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
NR LBD Fxr(4)
 
 
NR LBD GR(4)
 
 
BioAssay Types:
Confirmatory(73)
 
 
 
 
 
Summary(28)
 
 
 
Literature(1)
 
 
BioAssay Categories:
In vivo(1)
 
 
Toxicity(8)
 
 
 
 
ADME(2)
 
 
BioActivity Types:
Potency(94)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 104    Data Row: 104   Total Pages: 6   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210363]
Potency-Replicate_1 19.4938qHTS assay to identify small molecule agonists of the RXR signaling pathway [AID1159527, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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2
[SID48415069]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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3
[SID103621829]
GI50 29221.3Toxicity in Tetrahymena pyriformis [AID1094728, Type: confirmatory]
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4
[SID103621829]
Mutagenic activity in Salmonella Typhimurium TA100 assessed as logarithm of his+ revertant number increasing activity by amens test [AID384212, Type: Literature]
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5
[SID416046]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice [AID256, Type: other]
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6
[SID144210363]
Potency-Replicate_1 qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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7
[SID144210363]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cells [AID720675, Type: confirmatory]
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8
[SID144210363]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cell free culture [AID720681, Type: confirmatory]
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9
[SID144210363]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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10
[SID144210363]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cells [AID720687, Type: confirmatory]
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11
[SID144210363]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cell free culture [AID720685, Type: confirmatory]
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12
[SID144210363]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cell free culture [AID720684, Type: confirmatory]
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13
[SID144210363]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cell free culture [AID720683, Type: confirmatory]
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14
[SID144210363]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cell free culture [AID720682, Type: confirmatory]
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15
[SID144210363]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cells [AID720680, Type: confirmatory]
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16
[SID144210363]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cells [AID720679, Type: confirmatory]
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17
[SID144210363]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cells [AID720678, Type: confirmatory]
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18
[SID144210363]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cells [AID720674, Type: confirmatory]
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19
[SID144210363]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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20
[SID144210363]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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