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BioActivity Data for Compound Fluorouracil (CID 3385)

Filters: All Data » Active      
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BioActivity Outcomes:
Active(1383)
 
 
Top Targets:
TS Pyrimidine..(7)
 
 
P53(7)
 
 
NR LBD TR(5)
 
 
AAA(5)
 
 
recC(3)
 
 
BioAssay Types:
Literature(1075)
 
 
Confirmatory(184)
 
 
Screening(32)
 
 
Summary(8)
 
 
BioAssay Categories:
Biochemical(7)
 
 
Cell-based(1160)
 
 
Organism-base..(6)
 
 
Toxicity(590)
 
 
ADME(46)
 
 
In vitro(28)
 
 
In vivo(52)
 
 
BioActivity Types:
IC50(740)
 
 
Potency(46)
 
 
EC50(9)
 
 
Ki(3)
 
 
AC50(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1340    Data Row: 1383   Total Pages: 70   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103507642]
IC50 1.1e-06Cytotoxicity against mouse L1210 cells after 72 hrs by MTT assay [AID603110, Type: Literature]
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2
[SID103507642]
IC50 1.7e-06Cytotoxicity against mouse P388 cells after 72 hrs by MTT assay [AID603109, Type: Literature]
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3
[SID103507642]
IC50 2.7e-06Cytotoxicity against human HL60 cells after 72 hrs by MTT assay [AID603108, Type: Literature]
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4
[SID103507642]
IC50 7.7e-06Cytotoxicity against human KB cells after 72 hrs by MTT assay [AID603209, Type: Literature]
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5
[SID103507642]
IC50 0.00446Cytotoxicity against human KB cells by MTT assay [AID353084, Type: Literature]
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6
[SID103507642]
GI50 0.01Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay [AID766084, Type: Literature]
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7
[SID103507642]
GI50 0.01585Cytotoxicity against Homo sapiens (human) OVCAR3 cells after 48 hr by SRB assay [AID1085675, Type: confirmatory]
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8
[SID103507642]
GI50 0.01585Anticancer activity against human OVCAR-3 cells after 48 hrs by sulforhodamine B assay [AID438089, Type: Literature]
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9
[SID103507642]
GI50 0.01585Growth inhibition of human OVCAR-3 cells after 48 hrs by sulforhodamine B assay [AID538260, Type: Literature]
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10
[SID103507642]
IC50 0.016Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay [AID436373, Type: Literature]
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11
[SID103507642]
IC50 0.018Antiproliferative activity against human A431 cells after 48 hrs by MTT assay [AID436374, Type: Literature]
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12
[SID103507642]
GI50 0.02Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay [AID766115, Type: Literature]
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13
[SID103507642]
IC50 0.02Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 hrs by liquid scintillation counting [AID589982, Type: Literature]Thymidylate synthase [gi:136614]
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14
[SID103507642]
GI50 0.0238Cytotoxicity against human SR cells after 48 hrs by SRB assay [AID644642, Type: Literature]
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15
[SID103507642]
GI50 0.02399Anticancer activity against human SR cells after 48 hrs by sulforhodamine B assay [AID438057, Type: Literature]
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16
[SID103507642]
GI50 0.02399Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay [AID538161, Type: Literature]
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17
[SID103507642]
GI50 0.02399Cytotoxicity against Homo sapiens (human) SR cells after 48 hr by SRB assay [AID1085707, Type: confirmatory]
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18
[SID103507642]
IC50 0.03Antitumor activity against human MOLT4 cells after 24 hrs by MTT assay [AID475907, Type: Literature]
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19
[SID103507642]
GI50 0.04Growth inhibition of human RPMI8226 cells after 48 hrs by sulforhodamine B assay [AID766116, Type: Literature]
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20
[SID103507642]
GI50 0.04467Cytotoxicity against Homo sapiens (human) RPMI8226 cells after 48 hr by SRB assay [AID1085710, Type: confirmatory]
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