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Salicylic Acid (CID 338) - Compound BioActivity Data
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BioActivity Outcomes:
Active(30)
 
 
Inactive(1037)
 
 
Inconclusive(25)
 
 
Unspecified(454)
 
 
Top Targets:
7TM GPCR Srx(40)
 
 
 
 
7TM GPCR Srsx(37)
 
 
 
NR LBD ER(26)
 
 
 
 
NR LBD PPAR(24)
 
 
 
NR LBD AR(22)
 
 
 
 
BioAssay Types:
Confirmatory(545)
 
 
 
 
Screening(528)
 
 
 
 
Literature(236)
 
 
 
 
 
Summary(63)
 
 
BioActivity Types:
Potency(415)
 
 
 
 
IC50(170)
 
 
 
 
Ki(25)
 
 
 
EC50(10)
 
 
 
Kd(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1272    Data Row: 1546   Total Pages: 78   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103164944]
IC50 0.2Antihemorrhagic activity in ddY mouse assessed as inhibition of Protobothrops flavoviridis venom-induced hemorrhagic lesion formation compound incubated with venom for 10 mins and administered subcutaneously measured after 24 hrs [AID631927, Type: Literature]
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2
[SID103164944]
Ki 7.1Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydration assay [AID342476, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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3
[SID103164944]
Ki 7.12Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assay [AID331292, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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4
[SID103164944]
Ki 7.2Inhibition of mouse recombinant carbonic anhydrase 15 by stopped-flow CO2 hydrase assay [AID331293, Type: Literature]Carbonic anhydrase 15 [gi:30580362]
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5
[SID103164944]
Ki 8.8Inhibition of human carbonic anhydrase 12 catalytic domain by stopped-flow CO2 hydration assay [AID342484, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
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6
[SID103164944]
Ki 9.9Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydration assay [AID342475, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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7
[SID103164944]
Ki 9.92Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assay [AID331291, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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8
[SID103164944]
Ki 11.1Inhibition of human carbonic anhydrase 4 by stopped-flow CO2 hydration assay [AID342478, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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9
[SID103164944]
Ki 11.9Inhibition of human carbonic anhydrase 6 by stopped-flow CO2 hydration assay [AID342481, Type: Literature]Carbonic anhydrase 6 [gi:116241278]
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10
[SID103164944]
Ki 43.6516Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr [AID360149, Type: Literature]Solute carrier family 22 member 20 [gi:56404586]
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11
[SID103164944]
Ki 49.8Inhibition of human carbonic anhydrase 14 by stopped-flow CO2 hydration assay [AID342485, Type: Literature]Carbonic anhydrase 14 [gi:8928036]
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12
[SID8139912]
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624037, Type: screening]muscarinic acetylcholine receptor M5 [Homo sapiens] [gi:7108336]
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13
[SID8139912]
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 1 (CHRM1) [AID588814, Type: screening]muscarinic acetylcholine receptor M1 [Homo sapiens] [gi:37622910]
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14
[SID8139912]
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis [AID588726, Type: screening]Probable fructose-bisphosphate aldolase Fba [Mycobacterium tuberculosis H37Rv] [gi:15607504]
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15
[SID8139912]
Phenotypic HTS multiplex for antifungal efflux pump inhibitors with Validation compound Set [AID588506, Type: screening]
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16
[SID103164944]
Increase in ompX-lacZ expression in Escherichia coli JM109 assessed as ompX upregulation after 60 mins relative to control [AID369250, Type: Literature]
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17
[SID103164944]
Increase in ompX-lacZ expression in Escherichia coli JM109 assessed as increase in beta-galactosidase activity after 60 mins relative to control [AID369251, Type: Literature]
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18
[SID103164944]
Increase in ompX-lacZ expression in Enterobacter aerogenes ATCC 15038 assessed as ompX upregulation after 60 mins relative to control [AID369252, Type: Literature]
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19
[SID103164944]
Increase in ompX-lacZ expression in Enterobacter aerogenes ATCC 15038 assessed as increase in beta-galactosidase activity after 60 mins relative to control [AID369253, Type: Literature]
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20
[SID103164944]
Induction of ompX-lacZ expression in Enterobacter aerogenes ATCC 15038 assessed as total RNA content after 30 mins by RT-PCR [AID369255, Type: Literature]
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