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Sodium Azide (CID 33557) - Compound BioActivity Data
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BioActivity Outcomes:
Active(18)
 
 
Inactive(294)
 
 
Inconclusive(35)
 
 
Unspecified(41)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD ER(16)
 
 
 
NR LBD AR(16)
 
 
 
alpha CA I II..(13)
 
 
 
NR LBD Fxr(10)
 
 
 
BioAssay Types:
Confirmatory(274)
 
 
 
 
Literature(52)
 
 
 
 
Summary(48)
 
 
 
 
BioActivity Types:
Potency(273)
 
 
 
 
Ki(32)
 
 
 
IC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 291    Data Row: 388   Total Pages: 8   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103329735]
Ki 1.2Inhibition of human carbonic anhydrase 1 by Lineweaver-Burk curves [AID552171, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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2
[SID103329735]
Ki 1.2Inhibition of human carbonic anhydrase 1 after 15 mins by CO2 hydrase assay at pH 7.5 [AID587130, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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3
[SID103329735]
Ki 1.2Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 [AID598726, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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4
[SID103329735]
Ki 1.2Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay [AID714401, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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5
[SID103329735]
Ki 1.2Inhibition of human recombinant wild type CA1 by stopped-flow CO2 hydration method [AID724722, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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6
[SID103329735]
Ki 1.2Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay [AID730754, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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7
[SID103329735]
IC50 1.2Inhibition of full-length recombinant HIV1 integrase [AID569226, Type: Literature]
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8
[SID17390030]
Potency 2.5119Cell Viability - LYMP2-005 [AID967, Type: confirmatory]
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9
[SID103329735]
Ki 5Inhibition of human carbonic anhydrase 9 by Lineweaver-Burk curves [AID552168, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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10
[SID17390030]
Potency 17.7828qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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11
[SID144209659]
Potency-Replicate_1 53.1407qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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12
[SID144210344]
ER Potency (uM) 63.5221qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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13
[SID144209659]
Potency-Replicate_1 66.326qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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14
[SID144210344]
Potency-Replicate_1 68.5896qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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15
[SID103329735]
Increase in lactate production in MG63 cells at 1mM after 1 hr by ELISA [AID278887, Type: Literature]
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16
[SID48415472]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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17
[SID48413250]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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18
[SID103329735]
Increase in lactate production in primary human osteoblasts at 1 mM after 1 hr by ELISA [AID278886, Type: Literature]
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19
[SID103329735]
Ki 68Inhibition of human recombinant CA10 mutant after 15 mins by stopped-flow CO2 hydration method [AID724719, Type: Literature]
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20
[SID103329735]
IC50 257Inhibition of Trametes versicolor laccase assessed as production of dopachrome using 200 uM dopamine as substrate preincubated for 30 mins before substrate addition [AID628708, Type: Literature]Laccase precursor [gi:74626991]
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21
[SID103329735]
IC50 263Inhibition of Trametes versicolor laccase assessed as production of dopachrome using 100 uM epinephrine as substrate preincubated for 30 mins before substrate addition [AID628706, Type: Literature]Laccase precursor [gi:74626991]
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22
[SID103329735]
IC50 279Inhibition of Trametes versicolor laccase assessed as production of dopachrome using 300 uM L-dopa as substrate preincubated for 30 mins before substrate addition [AID628709, Type: Literature]Laccase precursor [gi:74626991]
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23
[SID103329735]
Ki 300Inhibition of human carbonic anhydrase 5 by Lineweaver-Burk curves [AID552169, Type: Literature]Carbonic anhydrase 5A, mitochondrial [gi:461680]
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24
[SID103329735]
IC50 329Inhibition of laccase in Cryptococcus neoformans var. grubii assessed as production of dopachrome using 100 uM epinephrine as substrate preincubated for 30 mins before substrate addition [AID628707, Type: Literature]
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25
[SID103329735]
Ki 340Inhibition of Sulfurihydrogenibium azorense alpha-carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay [AID714403, Type: Literature]
View
26
[SID103329735]
Ki 350Inhibition of Streptococcus pneumoniae beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay [AID552785, Type: Literature]
View
27
[SID103329735]
Ki 460Inhibition of Flaveria bidentis beta-carbonic anhydrase-1 preincubated for 15 mins by stopped flow CO2 hydration assay [AID730372, Type: Literature]
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28
[SID103329735]
Ki 490Inhibition of Sulfurihydrogenibium yellowstonense YO3AOP1 alpha-carbonic anhydrase-catalyzed CO2 hydration reaction preincubated for 15 mins by stopped flow CO2 hydrase assay [AID677270, Type: Literature]
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29
[SID103329735]
Ki 630Inhibition of human recombinant CA8 mutant after 15 mins by stopped-flow CO2 hydration method [AID724720, Type: Literature]
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30
[SID103329735]
Ki 750Inhibition of Salmonella Typhimurium carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 [AID598732, Type: Literature]
View
31
[SID103329735]
Ki 760Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay [AID730751, Type: Literature]
View
32
[SID103329735]
Ki 800Inhibition of Helicobacter pylori beta-carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay [AID730368, Type: Literature]
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33
[SID103329735]
Ki 830Inhibition of Helicobacter pylori alpha carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay [AID730752, Type: Literature]
View
34
[SID103329735]
Ki 830Inhibition of Helicobacter pylori alpha-carbonic anhydrase-catalyzed CO2 hydration reaction preincubated for 15 mins by stopped flow CO2 hydrase assay [AID677271, Type: Literature]
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35
[SID103329735]
Ki 830Inhibition of Leptonychotes weddellii alpha-carbonic anhydrase after 15 mins by CO2 hydrase assay at pH 7.5 [AID587132, Type: Literature]
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36
[SID103329735]
Ki 920Inhibition of Salmonella Typhimurium carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 [AID598731, Type: Literature]
View
37
[SID103329735]
Ki 1500Inhibition of human carbonic anhydrase 2 by Lineweaver-Burk curves [AID552172, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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38
[SID103329735]
Ki 1500Inhibition of human carbonic anhydrase 2 after 15 mins by CO2 hydrase assay at pH 7.5 [AID587131, Type: Literature]Carbonic anhydrase 2 [gi:115456]
View
39
[SID103329735]
Ki 1510Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 [AID598728, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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40
[SID103329735]
Ki 1510Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay [AID714400, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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41
[SID103329735]
Ki 1510Inhibition of human recombinant wild type CA2 by stopped-flow CO2 hydration method [AID724721, Type: Literature]Carbonic anhydrase 2 [gi:115456]
View
42
[SID103329735]
Ki 1510Inhibition of human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped flow CO2 hydration assay [AID730373, Type: Literature]Carbonic anhydrase 2 [gi:115456]
View
43
[SID103329735]
Ki 1510Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay [AID730753, Type: Literature]Carbonic anhydrase 2 [gi:115456]
View
44
[SID103329735]
Ki 1563Inhibition of Dicentrarchus labrax alpha-carbonic anhydrase by Lineweaver-Burk curves [AID552170, Type: Literature]
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45
[SID103329735]
Ki 27800Inhibition of Astrosclera willeyana recombinant GST-tagged astrosclerin 3 expressed in Escherichia coli BL21-DE3-RIPL cells preincubated for 15 mins measured for 10 to 100 secs by stopped flow CO2 hydration assay [AID647373, Type: Literature]
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46
[SID103329735]
IC50 46000Inhibition of HIV-1 integrase by colorimetry [AID684672, Type: Literature]
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47
[SID103329735]
Ki 55200Inhibition of human recombinant CA11 mutant after 15 mins by stopped-flow CO2 hydration method [AID724718, Type: Literature]
View
48
[SID103329735]
Ki 65100Inhibition of human carbonic anhydrase 4 by Lineweaver-Burk curves [AID552173, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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49
[SID103329735]
Mutagenic activity in Salmonella typhimurium TA 100 assessed as increase in revertants at 5 ug/plate after 48 hrs by Ames test relative to control [AID661625, Type: Literature]
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50
[SID17390030]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View