Bookmark and Share
Fenthion (CID 3346) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(13)
 
 
Inactive(861)
 
 
Inconclusive(64)
 
 
Unspecified(14)
 
 
Top Targets:
NR LBD PPAR(34)
 
 
 
NR LBD ER(25)
 
 
 
 
NR LBD AR(25)
 
 
 
NR LBD TR(19)
 
 
 
NR LBD VDR(19)
 
 
 
BioAssay Types:
Confirmatory(531)
 
 
 
 
 
Screening(238)
 
 
Literature(83)
 
 
 
 
Summary(72)
 
 
 
 
BioActivity Types:
Potency(542)
 
 
 
 
 
IC50(5)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 577    Data Row: 952   Total Pages: 48   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389877]
Potency 12.5893qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
2
[SID144204708]
AhR Potency (uM) 19.9496qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
3
[SID144210975]
Potency-Replicate_1 24.3365qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
4
[SID144210975]
Potency-Replicate_1 24.3365qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
View
5
[SID144210975]
AhR Potency (uM) 26.278qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
6
[SID144204708]
Potency-Replicate_1 26.6032qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
7
[SID144210975]
Potency-Replicate_1 27.306qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
8
[SID144208793]
Potency-Replicate_1 30.2955qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
9
[SID144208793]
AhR Potency (uM) 32.7123qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
10
[SID144208793]
Potency-Replicate_1 48.0151qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
11
[SID144208793]
Potency-Replicate_1 53.8738qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
12
[SID144210975]
Potency-Replicate_1 54.4827qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
13
[SID144210975]
Potency-Replicate_1 61.1306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
14
[SID160704111]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
View
15
[SID160704111]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
View
16
[SID160704111]
Dissociation constant, pKa of the compound at pH 7.3 [AID1091955, Type: Literature]
View
17
[SID160704111]
Apparent hydrophobicity, log D of the compound in Octanol-buffer [AID1091956, Type: Literature]
View
18
[SID160704111]
Apparent permeability of the compound by PAMPA [AID1091957, Type: Literature]
View
19
[SID160704111]
Hydrophobicity, log P of the compound in octanol-water by shaking-flask method [AID1091958, Type: Literature]
View
20
[SID160704111]
Ratio of EC50 for Daphnia magna to EC50 for first instar larvae of Cheumatopsyche brevilineata [AID1100305, Type: Literature]
View