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BioActivity Data for Compound Fenthion (CID 3346)

BioActivity Outcomes:
Active(14)
 
 
Inactive(919)
 
 
Inconclusive(68)
 
 
Unspecified(15)
 
 
Top Targets:
NR LBD PPAR(34)
 
 
 
NR LBD AR(25)
 
 
 
NR LBD ER(25)
 
 
 
 
7tm 4(25)
 
 
NR LBD VDR(19)
 
 
 
BioAssay Types:
Confirmatory(571)
 
 
 
 
 
Screening(246)
 
 
 
Summary(87)
 
 
 
 
Literature(83)
 
 
 
 
BioAssay Categories:
In vitro(2)
 
 
In vivo(1)
 
 
Biochemical(88)
 
 
 
Toxicity(61)
 
 
 
 
 
ADME(2)
 
 
Cell-based(90)
 
 
 
 
Organism-base..(8)
 
 
BioActivity Types:
Potency(589)
 
 
 
 
 
IC50(7)
 
 
AC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 609    Data Row: 1016   Total Pages: 51   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389877]
Potency 12.5893qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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2
[SID144204708]
AhR Potency (uM) 19.9496qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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3
[SID144210975]
Potency-Replicate_1 24.3365qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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4
[SID144210975]
Potency-Replicate_1 24.3365qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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5
[SID144210975]
AhR Potency (uM) 26.278qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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6
[SID144204708]
Potency-Replicate_1 26.6032qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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7
[SID144210975]
Potency-Replicate_1 27.306qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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8
[SID144208793]
Potency-Replicate_1 30.2955qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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9
[SID144208793]
AhR Potency (uM) 32.7123qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
10
[SID144208793]
Potency-Replicate_1 48.0151qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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11
[SID144208793]
Potency-Replicate_1 53.8738qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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12
[SID144210975]
Potency-Replicate_1 54.4827qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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13
[SID144210975]
Potency-Replicate_1 61.1306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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14
[SID170466807]
SW480 viability from Cell TiterGlo-screen [AID1117343, Type: screening]
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15
[SID160704111]
Apparent hydrophobicity, log D of the compound in Octanol-buffer [AID1091956, Type: Literature]
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16
[SID160704111]
Apparent permeability of the compound by PAMPA [AID1091957, Type: Literature]
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17
[SID160704111]
Hydrophobicity, log P of the compound in octanol-water by shaking-flask method [AID1091958, Type: Literature]
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18
[SID160704111]
Insecticidal activity against first-instar larvae of Cheumatopsyche brevilineata after 48 hr [AID1100306, Type: Literature]
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19
[SID160704111]
Insecticidal activity against Daphnia magna after 48 hr [AID1100309, Type: Literature]
View
20
[SID160704111]
Octanol-water partition coefficient, log KOW of the compound [AID1100307, Type: Literature]
View