Eugenol (CID 3314) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(9)
 
 
Inactive(406)
 
 
Inconclusive(31)
 
 
Unspecified(205)
 
 
Top Targets:
7TM GPCR Srx(12)
 
 
NR LBD TR(12)
 
 
7TM GPCR Srsx(10)
 
 
p450(10)
 
 
 
 
NR LBD PPAR(10)
 
 
 
BioAssay Types:
Confirmatory(288)
 
 
 
 
Literature(113)
 
 
 
 
 
Screening(9)
 
 
BioActivity Types:
Potency(246)
 
 
 
 
IC50(125)
 
 
 
Ki(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 468    Data Row: 651   Total Pages: 14   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103221475]
IC50 11Inhibition of COX1 [AID403341, Type: Literature]
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2
[SID26747361]
Potency 14.1254qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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3
[SID26747361]
Potency 14.1254qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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4
[SID103221475]
IC50 19Antagonist activity at AR in human MDA-kb2 cells co-transfected with MMTV-luc assessed as decrease in DHT-induced luciferase activity by reporter gene assay [AID473864, Type: Literature]Androgen receptor [gi:113830]
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5
[SID103221475]
IC50 19Antagonist activity at AR in human MDA-kb2 cells co-transfected with MMTV-luc assessed as decrease in DHT-induced luciferase activity by reporter gene assay [AID473864, Type: Literature]Androgen receptor [gi:113830]
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6
[SID103221475]
Ki 26.2Inhibition of Cochliobolus lunatus CYP53A15 expressed in Escherichia coli [AID404687, Type: Literature]
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7
[SID103221475]
IC50 27.5DPPH radical scavenging activity after 180 mins [AID382837, Type: Literature]
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8
[SID103221475]
IC50 34.6Inhibition of soybean 15-lipoxygenase [AID323558, Type: Literature]
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9
[SID103221475]
IC50 38.2Inhibition of soybean 15-lipoxygenase [AID392785, Type: Literature]
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10
[SID103221475]
IC50 38.2Inhibition of 15-lipoxygenase form soybean [AID395274, Type: Literature]
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11
[SID99301780]
 A screen for compounds that inhibit the CapD enzyme of Bacillus anthracis [AID492967, Type: other]gamma-glutamyltranspeptidase [Bacillus anthracis str. 'Ames Ancestor'] [gi:47566732]
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12
[SID103221475]
IC50 100Inhibitory concentration of compound on nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages [AID248765, Type: Literature]
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13
[SID103221475]
IC50 129Inhibition of COX2 by scintillation proximity assay [AID336477, Type: Literature]
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14
[SID103221475]
IC50 129Inhibition of COX2 [AID403340, Type: Literature]
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15
[SID103221475]
 Percentage inhibition against release of beta-hexosaminidase from RBL-2H3 cells at 100 uM from control [AID166551, Type: Literature]
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16
[SID103221475]
 Inhibition of COX1 at 1000 uM [AID403342, Type: Literature]
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17
[SID103221475]
 Inhibition of COX2 at 1000 uM [AID403343, Type: Literature]
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18
[SID103221475]
 Antifungal activity against Cochliobolus lunatus at 5 mM assessed as initial growth inhibition time [AID404681, Type: Literature]
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19
[SID103221475]
 Antifungal activity against Cochliobolus lunatus at 5 mM assessed as radial growth rate [AID404682, Type: Literature]
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20
[SID103221475]
IC50 DRUGMATRIX: Dopamine D4.2 radioligand binding (ligand: [3H] Spiperone) [AID625255, Type: other]D(4) dopamine receptor [gi:1345939]
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21
[SID103221475]
IC50 DRUGMATRIX: Dopamine D4.2 radioligand binding (ligand: [3H] Spiperone) [AID625255, Type: other]D(4) dopamine receptor [gi:1345939]
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22
[SID103221475]
IC50 DRUGMATRIX: Dopamine D4.2 radioligand binding (ligand: [3H] Spiperone) [AID625255, Type: other]D(4) dopamine receptor [gi:1345939]
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23
[SID103221475]
IC50 DRUGMATRIX: Endothelin ETA radioligand binding (ligand: [125I] Endothelin-1) [AID625257, Type: other]Endothelin-1 receptor [gi:119606]
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24
[SID103221475]
IC50 DRUGMATRIX: Endothelin ETA radioligand binding (ligand: [125I] Endothelin-1) [AID625257, Type: other]Endothelin-1 receptor [gi:119606]
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25
[SID103221475]
IC50 DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625184, Type: other]Epidermal growth factor receptor [gi:2811086]
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26
[SID103221475]
IC50 DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625184, Type: other]Epidermal growth factor receptor [gi:2811086]
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27
[SID103221475]
IC50 DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625184, Type: other]Epidermal growth factor receptor [gi:2811086]
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28
[SID103221475]
 DRUGMATRIX: Peptidase, ELA2 (Neutrophil Elastase 2) enzyme inhibition (substrate: N-MeOSuc-Ala-Ala-Pro-Val-pNA) [AID625176, Type: other]Neutrophil elastase [gi:119292]
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29
[SID103221475]
IC50 DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625186, Type: other]Receptor tyrosine-protein kinase erbB-2 [gi:119533]
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30
[SID103221475]
IC50 DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625186, Type: other]Receptor tyrosine-protein kinase erbB-2 [gi:119533]
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31
[SID103221475]
IC50 DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol) [AID625258, Type: other]Estrogen receptor [gi:544257]
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32
[SID103221475]
IC50 DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol) [AID625258, Type: other]Estrogen receptor [gi:544257]
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33
[SID103221475]
IC50 DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol) [AID625258, Type: other]Estrogen receptor [gi:544257]
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34
[SID103221475]
IC50 DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol) [AID625258, Type: other]Estrogen receptor [gi:544257]
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35
[SID103221475]
IC50 DRUGMATRIX: Vascular Endothelinal Growth Factor (VEGF) radioligand binding (ligand: [125I] VEGF) [AID625231, Type: other]Vascular endothelial growth factor receptor 1 [gi:143811474]
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36
[SID103221475]
IC50 DRUGMATRIX: Vascular Endothelinal Growth Factor (VEGF) radioligand binding (ligand: [125I] VEGF) [AID625231, Type: other]Vascular endothelial growth factor receptor 1 [gi:143811474]
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37
[SID103221475]
IC50 DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625185, Type: other]Tyrosine-protein kinase Fyn [gi:125370]
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38
[SID103221475]
IC50 DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625185, Type: other]Tyrosine-protein kinase Fyn [gi:125370]
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39
[SID103221475]
IC50 DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) [AID625263, Type: other]Glucocorticoid receptor [gi:121069]
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40
[SID103221475]
IC50 DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) [AID625263, Type: other]Glucocorticoid receptor [gi:121069]
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41
[SID103221475]
IC50 DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) [AID625263, Type: other]Glucocorticoid receptor [gi:121069]
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42
[SID103221475]
IC50 DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) [AID625263, Type: other]Glucocorticoid receptor [gi:121069]
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43
[SID103221475]
IC50 DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine) [AID625269, Type: other]Histamine H1 receptor [gi:547645]
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44
[SID103221475]
IC50 DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine) [AID625269, Type: other]Histamine H1 receptor [gi:547645]
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45
[SID103221475]
IC50 DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine) [AID625270, Type: other]Histamine H2 receptor [gi:123120]
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46
[SID103221475]
IC50 DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine) [AID625270, Type: other]Histamine H2 receptor [gi:123120]
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47
[SID103221475]
IC50 DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine) [AID625270, Type: other]Histamine H2 receptor [gi:123120]
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48
[SID103221475]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin) [AID625192, Type: other]5-hydroxytryptamine receptor 2A [gi:543727]
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49
[SID103221475]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin) [AID625192, Type: other]5-hydroxytryptamine receptor 2A [gi:543727]
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50
[SID103221475]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin) [AID625192, Type: other]5-hydroxytryptamine receptor 2A [gi:543727]
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