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Eugenol (CID 3314) - Compound BioActivity Data
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BioActivity Outcomes:
Active(9)
 
 
Inactive(664)
 
 
Inconclusive(65)
 
 
Unspecified(205)
 
 
Top Targets:
NR LBD PPAR(34)
 
 
 
NR LBD AR(29)
 
 
 
 
 
NR LBD ER(27)
 
 
 
 
NR LBD TR(21)
 
 
NR LBD VDR(19)
 
 
 
BioAssay Types:
Confirmatory(505)
 
 
 
 
Literature(145)
 
 
 
 
 
Summary(72)
 
 
 
Screening(9)
 
 
BioActivity Types:
Potency(513)
 
 
 
 
IC50(125)
 
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 566    Data Row: 943   Total Pages: 19   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103221475]
IC50 11Inhibition of COX1 [AID403341, Type: Literature]
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2
[SID26747361]
Potency 14.1254qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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3
[SID103221475]
IC50 19Antagonist activity at AR in human MDA-kb2 cells co-transfected with MMTV-luc assessed as decrease in DHT-induced luciferase activity by reporter gene assay [AID473864, Type: Literature]Androgen receptor [gi:113830]
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4
[SID103221475]
Ki 26.2Inhibition of Cochliobolus lunatus CYP53A15 expressed in Escherichia coli [AID404687, Type: Literature]
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5
[SID103221475]
IC50 27.5DPPH radical scavenging activity after 180 mins [AID382837, Type: Literature]
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6
[SID103221475]
IC50 34.6Inhibition of soybean 15-lipoxygenase [AID323558, Type: Literature]
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7
[SID103221475]
IC50 38.2Inhibition of soybean 15-lipoxygenase [AID392785, Type: Literature]
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8
[SID103221475]
IC50 38.2Inhibition of 15-lipoxygenase form soybean [AID395274, Type: Literature]
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9
[SID99301780]
A screen for compounds that inhibit the CapD enzyme of Bacillus anthracis [AID492967, Type: other]gamma-glutamyltranspeptidase [Bacillus anthracis str. 'Ames Ancestor'] [gi:47566732]
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10
[SID103221475]
IC50 100Inhibitory concentration of compound on nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages [AID248765, Type: Literature]
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11
[SID103221475]
IC50 129Inhibition of COX2 by scintillation proximity assay [AID336477, Type: Literature]
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12
[SID103221475]
IC50 129Inhibition of COX2 [AID403340, Type: Literature]
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13
[SID103221475]
Km 1570Binding affinity against human UDP Glucuronosyltransferase 1A4 (UGT1A4) [AID214939, Type: Literature]
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14
[SID103221475]
Percentage inhibition against release of beta-hexosaminidase from RBL-2H3 cells at 100 uM from control [AID166551, Type: Literature]
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15
[SID103221475]
Percent inhibition of nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages at 100 uM of compound [AID252044, Type: Literature]
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16
[SID103221475]
Inhibition of COX2 at 100 uM by scintillation proximity assay [AID336478, Type: Literature]
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17
[SID103221475]
Antifungal activity against Microsporum canis C 112 by agar dilution method [AID376055, Type: Literature]
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18
[SID103221475]
Insecticidal activity in adult Cylas formicarius elegantulus measured per insect after 24 hrs [AID378234, Type: Literature]
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19
[SID103221475]
Antimicrobial activity against Escherichia coli UNSWO24101 after 48 hrs [AID399141, Type: Literature]
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20
[SID103221475]
Antimicrobial activity against Micrococcus luteus ATCC 9341 after 48 hrs [AID399142, Type: Literature]
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21
[SID103221475]
Antimicrobial activity against Staphylococcus aureus ATCC 6538 after 48 hrs [AID399143, Type: Literature]
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22
[SID103221475]
Antimicrobial activity against Saccharomyces cerevisiae UNSA Y-40 after 48 hrs [AID399144, Type: Literature]
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23
[SID103221475]
Inhibition of COX1 at 1000 uM [AID403342, Type: Literature]
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24
[SID103221475]
Inhibition of COX2 at 1000 uM [AID403343, Type: Literature]
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25
[SID103221475]
Antifungal activity against Cochliobolus lunatus at 5 mM assessed as initial growth inhibition time [AID404681, Type: Literature]
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26
[SID103221475]
Antifungal activity against Cochliobolus lunatus at 5 mM assessed as radial growth rate [AID404682, Type: Literature]
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27
[SID17389879]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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28
[SID103221475]
IC50 DRUGMATRIX: Nicotinic Acetylcholine radioligand binding (ligand: [125I] Epibatidine) [AID625158, Type: other]
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29
[SID103221475]
DRUGMATRIX: Phorbol Ester radioligand binding (ligand: [3H] PDBu) [AID625164, Type: other]
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30
[SID103221475]
IC50 DRUGMATRIX: Phosphodiesterase PDE3 enzyme inhibition (substrate: [3H]cAMP + cAMP) [AID625165, Type: other]
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31
[SID103221475]
IC50 DRUGMATRIX: Phosphodiesterase PDE4 enzyme inhibition (substrate: [3H]cAMP + cAMP) [AID625166, Type: other]
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32
[SID103221475]
DRUGMATRIX: Platelet-Derived Growth Factor (PDGF) radioligand binding (ligand: [125I] PDGF) [AID625169, Type: other]
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33
[SID103221475]
IC50 DRUGMATRIX: Potassium Channel [KATP] radioligand binding (ligand: [3H] Glyburide) [AID625170, Type: other]
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34
[SID103221475]
DRUGMATRIX: Purinergic P2X radioligand binding (ligand: [3H] alpha, beta-Methylene-ATP) [AID625189, Type: other]
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35
[SID103221475]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT) [AID625190, Type: other]
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36
[SID103221475]
IC50 DRUGMATRIX: Sodium/nucleoside co-transporter radioligand binding (ligand: nitrobenzylthioinosine) [AID625197, Type: other]
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37
[SID103221475]
IC50 DRUGMATRIX: ATPase, Na+/K+ enzyme inhibition (substrate: ATP) [AID625210, Type: other]
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38
[SID103221475]
DRUGMATRIX: Atrial Natriuretic Factor (ANF) radioligand binding (ligand: [125I] ANF (rat)) [AID625211, Type: other]
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39
[SID103221475]
IC50 DRUGMATRIX: beta-Lactamase enzyme inhibition (substrate: Nitrocefin) [AID625212, Type: other]
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40
[SID103221475]
IC50 DRUGMATRIX: Calcium Channel Type L, Benzothiazepine radioligand binding (ligand: [3H] Diltiazem) [AID625215, Type: other]
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41
[SID103221475]
IC50 DRUGMATRIX: Calcium Channel Type L, Dihydropyridine radioligand binding (ligand: [3H] Nitrendipine) [AID625216, Type: other]
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42
[SID103221475]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT3 radioligand binding (ligand: [3H] GR-65630) [AID625219, Type: other]
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43
[SID103221475]
IC50 DRUGMATRIX: Sigma2 radioligand binding (ligand: [3H] Ifenprodil) [AID625224, Type: other]
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44
[SID103221475]
IC50 DRUGMATRIX: Sodium Channel, Site 2 radioligand binding (ligand: [3H] Batrachotoxin) [AID625225, Type: other]
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45
[SID103221475]
DRUGMATRIX: Tumor Necrosis Factor (TNF), Non-Selective radioligand binding (ligand: [125I] TNF-alpha) [AID625230, Type: other]
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46
[SID103221475]
IC50 DRUGMATRIX: Calcium Channel Type L, Phenylalkylamine radioligand binding (ligand: [3H] (-)-Desmethoxyverapamil (D-888)) [AID625234, Type: other]
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47
[SID103221475]
IC50 DRUGMATRIX: GABAA, Muscimol, Central radioligand binding (ligand: [3H] Muscimol) [AID625260, Type: other]
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48
[SID103221475]
IC50 DRUGMATRIX: GABAA, Flunitrazepam, Central radioligand binding (ligand: [3H] Flunitrazepam) [AID625261, Type: other]
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49
[SID103221475]
IC50 DRUGMATRIX: GABAA, Chloride Channel, TBOB radioligand binding (ligand: [3H] TBOB) [AID625262, Type: other]
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50
[SID103221475]
IC50 DRUGMATRIX: Glutamate, AMPA radioligand binding (ligand: [3H] AMPA) [AID625264, Type: other]
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