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BioActivity Data for Compound Eugenol (CID 3314)

BioActivity Outcomes:
Active(12)
 
 
Inactive(716)
 
 
Inconclusive(52)
 
 
Unspecified(312)
 
 
Top Targets:
NR LBD PPAR(34)
 
 
 
7tm 4(32)
 
 
 
NR LBD AR(29)
 
 
 
 
 
NR LBD ER(27)
 
 
 
 
NR LBD TR(21)
 
 
BioAssay Types:
Confirmatory(646)
 
 
 
 
 
Literature(223)
 
 
 
 
 
Summary(78)
 
 
 
Screening(17)
 
 
BioAssay Categories:
In vitro(145)
 
 
 
In vivo(4)
 
 
 
Biochemical(146)
 
 
 
 
Toxicity(70)
 
 
 
 
ADME(16)
 
 
Cell-based(100)
 
 
 
 
 
Organism-base..(2)
 
 
BioActivity Types:
Potency(539)
 
 
 
 
IC50(125)
 
 
 
AC50(6)
 
 
 
Kd(2)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 697    Data Row: 1092   Total Pages: 55   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170484057]
Kd 0.28Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Apis Mellifera Obp14 In Complex With The Odorant Eugenol (2-Methoxy- 4(2-Propenyl)-Phenol) [gi:358439796]
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2
[SID170484057]
Kd 0.28Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Apis Mellifera Obp14 In Complex With The Odorant Eugenol (2-Methoxy- 4(2-Propenyl)-Phenol) [gi:358439796]
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3
[SID103221475]
IC50 11Inhibition of COX1 [AID403341, Type: Literature]
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4
[SID26747361]
Potency 14.1254qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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5
[SID103221475]
IC50 19Antagonist activity at AR in human MDA-kb2 cells co-transfected with MMTV-luc assessed as decrease in DHT-induced luciferase activity by reporter gene assay [AID473864, Type: Literature]Androgen receptor [gi:113830]
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6
[SID103221475]
Ki 26.2Inhibition of Cochliobolus lunatus CYP53A15 expressed in Escherichia coli [AID404687, Type: Literature]
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7
[SID103221475]
IC50 27.5DPPH radical scavenging activity after 180 mins [AID382837, Type: Literature]
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8
[SID103221475]
IC50 34.6Inhibition of soybean 15-lipoxygenase [AID323558, Type: Literature]
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9
[SID103221475]
IC50 38.2Inhibition of soybean 15-lipoxygenase [AID392785, Type: Literature]
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10
[SID103221475]
IC50 38.2Inhibition of 15-lipoxygenase form soybean [AID395274, Type: Literature]
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11
[SID103221475]
Acaricidal activity against Dermatophagoides pteronyssinus assessed as mortality at 6.4 to 8 ug/cm2 after 24 to 72 hr by fabric disk assay relative to untreated control [AID1102059, Type: Literature]
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12
[SID99301780]
A screen for compounds that inhibit the CapD enzyme of Bacillus anthracis [AID492967, Type: other]gamma-glutamyltranspeptidase [Bacillus anthracis str. 'Ames Ancestor'] [gi:47566732]
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13
[SID103221475]
IC50 100Inhibitory concentration of compound on nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages [AID248765, Type: Literature]
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14
[SID103221475]
IC50 129Inhibition of COX2 by scintillation proximity assay [AID336477, Type: Literature]
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15
[SID103221475]
IC50 129Inhibition of COX2 [AID403340, Type: Literature]
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16
[SID103221475]
Km 1570Binding affinity against human UDP Glucuronosyltransferase 1A4 (UGT1A4) [AID214939, Type: Literature]
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17
[SID103221475]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1B radioligand binding (ligand: [125I] Cyanopindolol) [AID625191, Type: confirmatory]5-hydroxytryptamine receptor 1B [gi:112815]
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18
[SID103221475]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine) [AID625218, Type: confirmatory]5-hydroxytryptamine receptor 2C [gi:112816]
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19
[SID103221475]
IC50 DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine) [AID625193, Type: confirmatory]Acetylcholinesterase [gi:113037]
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20
[SID103221475]
IC50 DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625151, Type: confirmatory]Muscarinic acetylcholine receptor M1 [gi:113118]
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