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Eugenol (CID 3314) - Compound BioActivity Data
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BioActivity Outcomes:
Active(11)
 
 
Inactive(678)
 
 
Inconclusive(53)
 
 
Unspecified(207)
 
 
Top Targets:
NR LBD PPAR(34)
 
 
 
NR LBD AR(29)
 
 
 
 
 
NR LBD ER(27)
 
 
 
 
NR LBD TR(21)
 
 
NR LBD VDR(19)
 
 
 
BioAssay Types:
Confirmatory(622)
 
 
 
 
 
Literature(150)
 
 
 
 
 
Summary(72)
 
 
 
Screening(9)
 
 
BioActivity Types:
Potency(515)
 
 
 
 
IC50(125)
 
 
 
Kd(2)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 570    Data Row: 949   Total Pages: 48   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170484057]
Kd 0.28Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Apis Mellifera Obp14 In Complex With The Odorant Eugenol (2-Methoxy- 4(2-Propenyl)-Phenol) [gi:358439796]
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2
[SID170484057]
Kd 0.28Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Apis Mellifera Obp14 In Complex With The Odorant Eugenol (2-Methoxy- 4(2-Propenyl)-Phenol) [gi:358439796]
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3
[SID103221475]
IC50 11Inhibition of COX1 [AID403341, Type: Literature]
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4
[SID26747361]
Potency 14.1254qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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5
[SID103221475]
IC50 19Antagonist activity at AR in human MDA-kb2 cells co-transfected with MMTV-luc assessed as decrease in DHT-induced luciferase activity by reporter gene assay [AID473864, Type: Literature]Androgen receptor [gi:113830]
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6
[SID103221475]
Ki 26.2Inhibition of Cochliobolus lunatus CYP53A15 expressed in Escherichia coli [AID404687, Type: Literature]
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7
[SID103221475]
IC50 27.5DPPH radical scavenging activity after 180 mins [AID382837, Type: Literature]
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8
[SID103221475]
IC50 34.6Inhibition of soybean 15-lipoxygenase [AID323558, Type: Literature]
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9
[SID103221475]
IC50 38.2Inhibition of soybean 15-lipoxygenase [AID392785, Type: Literature]
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10
[SID103221475]
IC50 38.2Inhibition of 15-lipoxygenase form soybean [AID395274, Type: Literature]
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11
[SID99301780]
A screen for compounds that inhibit the CapD enzyme of Bacillus anthracis [AID492967, Type: other]gamma-glutamyltranspeptidase [Bacillus anthracis str. 'Ames Ancestor'] [gi:47566732]
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12
[SID103221475]
IC50 100Inhibitory concentration of compound on nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages [AID248765, Type: Literature]
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13
[SID103221475]
IC50 129Inhibition of COX2 by scintillation proximity assay [AID336477, Type: Literature]
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14
[SID103221475]
IC50 129Inhibition of COX2 [AID403340, Type: Literature]
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15
[SID103221475]
Km 1570Binding affinity against human UDP Glucuronosyltransferase 1A4 (UGT1A4) [AID214939, Type: Literature]
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16
[SID103221475]
Percentage inhibition against release of beta-hexosaminidase from RBL-2H3 cells at 100 uM from control [AID166551, Type: Literature]
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17
[SID103221475]
Percent inhibition of nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages at 100 uM of compound [AID252044, Type: Literature]
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18
[SID103221475]
Inhibition of COX2 at 100 uM by scintillation proximity assay [AID336478, Type: Literature]
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19
[SID103221475]
Antifungal activity against Microsporum canis C 112 by agar dilution method [AID376055, Type: Literature]
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20
[SID103221475]
Insecticidal activity in adult Cylas formicarius elegantulus measured per insect after 24 hrs [AID378234, Type: Literature]
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