ethylenediamine (CID 3301) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Inactive(236)
 
 
Inconclusive(4)
 
 
Unspecified(15)
 
 
Top Targets:
NR LBD PPAR(5)
 
 
NR LBD TR(4)
 
 
P53(3)
 
 
NR LBD VDR(3)
 
 
NR LBD ROR li..(3)
 
 
BioAssay Types:
Confirmatory(168)
 
 
 
 
Literature(77)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(132)
 
 
 
 
IC50(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 188    Data Row: 257   Total Pages: 6   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389605]
Potency 0.1995qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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2
[SID17389605]
Potency 0.1995qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID17389605]
Potency 0.1995qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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4
[SID17389605]
Potency 0.1995qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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5
[SID48415073]
 DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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6
[SID103214369]
IC50 15500Inhibition of [3H]farnesyl pyrophosphate binding to human farnesyltransferase [AID72823, Type: Literature]Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha [gi:1346694]
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7
[SID103214369]
 Antibacterial activity against Staphylococcus aureus after 24 hrs by twofold serial dilution method [AID450457, Type: Literature]
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8
[SID103214369]
 Antibacterial activity against Bacillus subtilis after 24 hrs by twofold serial dilution method [AID450458, Type: Literature]
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9
[SID103214369]
 Antibacterial activity against Serratia marcescens after 24 hrs by twofold serial dilution method [AID450459, Type: Literature]
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10
[SID103214369]
 Antibacterial activity against Pseudomonas aeruginosa after 24 hrs by twofold serial dilution method [AID450460, Type: Literature]
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11
[SID103214369]
 Antibacterial activity against Escherichia coli after 24 hrs by twofold serial dilution method [AID450461, Type: Literature]
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12
[SID17389605]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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13
[SID17389605]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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14
[SID103214369]
 Inhibitory activity against murine gelatinase B at 5 mM was determined [AID74488, Type: Literature]
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15
[SID103214369]
 Cytotoxicity against mouse J774 macrophage assessed as cell viability at 1 ug/mL after 48 hrs by MTT assay [AID448381, Type: Literature]
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16
[SID103214369]
 Cytotoxicity against mouse J774 macrophage assessed as cell viability at 10 ug/mL after 48 hrs by MTT assay [AID448530, Type: Literature]
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17
[SID103214369]
 Cytotoxicity against mouse J774 macrophage assessed as cell viability at 100 ug/mL after 48 hrs by MTT assay [AID448531, Type: Literature]
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18
[SID103214369]
 Cytotoxicity against Mycobacterium bovis Bacillus Calmette-Guerin infected mouse J774 macrophage assessed as cell viability at 1 ug/mL after 48 hrs by MTT assay [AID448532, Type: Literature]
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19
[SID103214369]
 Cytotoxicity against Mycobacterium bovis Bacillus Calmette-Guerin infected mouse J774 macrophage assessed as cell viability at 10 ug/mL after 48 hrs by MTT assay [AID448533, Type: Literature]
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20
[SID103214369]
 Cytotoxicity against Mycobacterium bovis Bacillus Calmette-Guerin infected mouse J774 macrophage assessed as cell viability at 100 ug/mL after 48 hrs by MTT assay [AID448534, Type: Literature]
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21
[SID103214369]
 Antimicrobial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as minimum inhibitory concentration after 24 hrs by micro plate Alamar blue assay [AID448380, Type: Literature]
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22
[SID17389605]
Potency S16 Schwann cell viability assay (CellTiter-Glo assay) [AID624031, Type: confirmatory]
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23
[SID17389605]
Potency qHTS Assay for Modulators of Lamin A Splicing [AID1487, Type: confirmatory]prelamin-A/C isoform 3 [Homo sapiens] [gi:27436948]
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24
[SID17389605]
 qHTS Assay for Tau Filament Binding [AID596, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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25
[SID17389605]
 qHTS Assay for Tau Filament Binding [AID596, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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26
[SID17389605]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide [AID1766, Type: confirmatory]MEN1 gene product [Homo sapiens] [gi:18860839]
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27
[SID17389605]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]MEN1 gene product [Homo sapiens] [gi:18860839]
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28
[SID17389605]
Potency qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction [AID2662, Type: confirmatory]MLL gene product [Homo sapiens] [gi:56550039]
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29
[SID17389605]
Potency qHTS assay for small molecule antagonists of androgen receptor signaling [AID588516, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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30
[SID17389605]
Potency qHTS assay for small molecule antagonists of androgen receptor signaling [AID588516, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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31
[SID17389605]
Potency qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM) [AID2528, Type: confirmatory]Bloom syndrome protein [Homo sapiens] [gi:4557365]
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32
[SID17389605]
Potency qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1 [AID900, Type: confirmatory]caspase-1 isoform alpha precursor [Homo sapiens] [gi:15431328]
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33
[SID17389605]
Potency qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1 [AID900, Type: confirmatory]caspase-1 isoform alpha precursor [Homo sapiens] [gi:15431328]
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34
[SID17389605]
Potency qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-7 [AID889, Type: confirmatory]Caspase-7 [gi:1730092]
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35
[SID17389605]
Potency qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-7 [AID889, Type: confirmatory]Caspase-7 [gi:1730092]
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36
[SID17389605]
Potency qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450, family 3, subfamily A, polypeptide 4 [Homo sapiens] [gi:13435386]
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37
[SID17389605]
Potency qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450, family 3, subfamily A, polypeptide 4 [Homo sapiens] [gi:13435386]
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38
[SID17389605]
Potency qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450, family 3, subfamily A, polypeptide 4 [Homo sapiens] [gi:13435386]
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39
[SID17389605]
Potency qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450, family 3, subfamily A, polypeptide 4 [Homo sapiens] [gi:13435386]
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40
[SID17389605]
Potency qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450, family 3, subfamily A, polypeptide 4 [Homo sapiens] [gi:13435386]
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41
[SID17389605]
Potency qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450, family 3, subfamily A, polypeptide 4 [Homo sapiens] [gi:13435386]
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42
[SID144204696]
 qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
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43
[SID144204696]
 qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
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44
[SID144204696]
 qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
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45
[SID144204696]
 qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
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46
[SID144204696]
 qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
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47
[SID144204696]
 qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
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48
[SID144204696]
 qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
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49
[SID144204696]
 qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
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50
[SID17389605]
Potency qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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