Bookmark and Share
sirodesmin (CID 325517) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(72)
 
 
Inactive(206)
 
 
Inconclusive(12)
 
 
Unspecified(7)
 
 
Top Targets:
7tm 4(23)
 
 
 
 
Hexokinase 2(6)
 
 
 
RasGEF(4)
 
 
CD36(4)
 
 
 
Troponin(4)
 
 
BioAssay Types:
Screening(167)
 
 
 
 
Confirmatory(105)
 
 
 
 
 
Literature(9)
 
 
BioActivity Types:
Potency(78)
 
 
 
 
 
IC50(19)
 
 
 
 
AC50(3)
 
 
 
EC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 251    Data Row: 297   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID92764147]
Potency 0.1458qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
2
[SID92764147]
Potency 0.1636qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
3
[SID92764147]
EC50_Mean 0.212Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) [AID504730, Type: confirmatory]putative hexokinase HKDC1 [Homo sapiens] [gi:156151420]
View
4
[SID92764147]
Potency 0.4611A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
View
5
[SID92764147]
Potency 0.5623qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
View
6
[SID92764147]
Potency 0.5805qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
View
7
[SID92764147]
Potency 0.6513qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
View
8
[SID92764147]
Potency 0.7943qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
View
9
[SID92764147]
AC50_uM 1.06Development of Small Molecule Probes of the Histone Methyltransferase, NSD2 Measured in Biochemical System Using Plate Reader - 7053-01_Inhibitor_Dose_CherryPick_Activity [AID1053173, Type: confirmatory]histone-lysine N-methyltransferase NSD2 isoform 1 [Homo sapiens] [gi:109633019]
View
10
[SID92764147]
Potency 1.4125qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
View
11
[SID92764147]
Potency 1.5849qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
View
12
[SID92764147]
Potency 2.3778qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
View
13
[SID92764147]
Potency 3.1623qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
View
14
[SID92764147]
Potency 3.5277qHTS for inhibitors of Vif-A3F interactions: Cherry picks counterscreen [AID651815, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3F isoform a [Homo sapiens] [gi:22907044]
View
15
[SID92764147]
IC50 3.639Fluorescence-based cell-based high throughput dose response assay for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and the receptor-interacting serine-threonine kinase 2 (RIPK2) [AID651553, Type: confirmatory]caspase recruitment domain family, member 15 [Homo sapiens] [gi:119603173]
View
16
[SID92764147]
IC50 3.639Fluorescence-based cell-based high throughput dose response assay for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and the receptor-interacting serine-threonine kinase 2 (RIPK2) [AID651553, Type: confirmatory]receptor-interacting serine/threonine-protein kinase 2 [Homo sapiens] [gi:4506537]
View
17
[SID92764147]
AC50_uM 5.611HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_CherryPick_Activity [AID493194, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
View
18
[SID92764147]
Potency 6.2733qHTS for inhibitors of Vif-A3F interactions: Cherry picks [AID651814, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3F isoform a [Homo sapiens] [gi:22907044]
View
19
[SID92764147]
Potency 7.3078Nrf2 qHTS screen for inhibitors: counterscreen for cytotoxicity [AID504648, Type: confirmatory]
View
20
[SID92764147]
Potency 12.5168qHTS for inhibitors of Vif-A3G interactions: Cherry picks counterscreen [AID651813, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3G [Homo sapiens] [gi:13399304]
View