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ZINC02483658 (CID 3245690) - Compound BioActivity Data
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BioActivity Outcomes:
Active(35)
 
 
Inactive(830)
 
 
Inconclusive(36)
 
 
Unspecified(3)
 
 
Top Targets:
7tm 4(48)
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
NR LBD PPAR(11)
 
 
 
Tryp SPc(11)
 
 
BioAssay Types:
Screening(574)
 
 
 
 
Confirmatory(297)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(202)
 
 
 
 
 
IC50(53)
 
 
 
 
EC50(17)
 
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 792    Data Row: 904   Total Pages: 46   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID4252095]
IC50 0.81255TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists [AID463256, Type: confirmatory]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
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2
[SID4252095]
IC50 1.23Counterscreen for NR2E3 inverse agonists: TR-FRET-based biochemical high throughput dose response assay to identify inverse agonists of the interaction between peroxisome proliferator-activated receptor gamma (PPARg) and nuclear receptor co-repressor 2 (NCOR2) [AID463257, Type: confirmatory]nuclear receptor corepressor 2 isoform 2 [Homo sapiens] [gi:116256445]
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3
[SID4252095]
IC50 1.23Counterscreen for NR2E3 inverse agonists: TR-FRET-based biochemical high throughput dose response assay to identify inverse agonists of the interaction between peroxisome proliferator-activated receptor gamma (PPARg) and nuclear receptor co-repressor 2 (NCOR2) [AID463257, Type: confirmatory]peroxisome proliferator-activated receptor gamma isoform 2 [Homo sapiens] [gi:20336229]
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4
[SID4252095]
EC50 3.979TR-FRET dose response biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPAR gamma): non-selective agonists [AID1681, Type: confirmatory]peroxisome proliferator-activated receptor gamma isoform 2 [Homo sapiens] [gi:20336229]
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5
[SID4252095]
EC50 3.979TR-FRET dose response biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPAR gamma): non-selective agonists [AID1681, Type: confirmatory]NCOA2 protein [Homo sapiens] [gi:62201602]
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6
[SID4252095]
EC50 4.06TR-FRET dose response biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPAR gamma): non-selective agonists [AID1679, Type: confirmatory]peroxisome proliferator-activated receptor gamma isoform 2 [Homo sapiens] [gi:20336229]
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7
[SID4252095]
EC50 4.06TR-FRET dose response biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPAR gamma): non-selective agonists [AID1679, Type: confirmatory]nuclear receptor coactivator 1 [Homo sapiens] [gi:152112968]
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8
[SID104219245]
Potency 8.9125qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression [AID624202, Type: confirmatory]BRCA1 [Homo sapiens] [gi:1698399]
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9
[SID4252095]
Potency 25.1189qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia [AID485349, Type: confirmatory]serine-protein kinase ATM [Homo sapiens] [gi:71902540]
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10
[SID4252095]
Potency 89.1251qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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11
[SID4252095]
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma) [AID631, Type: screening]peroxisome proliferator-activated receptor gamma isoform 2 [Homo sapiens] [gi:20336229]
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12
[SID4252095]
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma) [AID731, Type: screening]peroxisome proliferator-activated receptor gamma isoform 2 [Homo sapiens] [gi:20336229]
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13
[SID4252095]
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma) [AID1049, Type: other]peroxisome proliferator-activated receptor gamma isoform 2 [Homo sapiens] [gi:20336229]
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14
[SID4252095]
Confirmation biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma) [AID1297, Type: screening]peroxisome proliferator-activated receptor gamma isoform 2 [Homo sapiens] [gi:20336229]
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15
[SID4252095]
Confirmation biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma) [AID1300, Type: screening]peroxisome proliferator-activated receptor gamma isoform 2 [Homo sapiens] [gi:20336229]
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16
[SID4252095]
Confirmation biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma) [AID1301, Type: screening]peroxisome proliferator-activated receptor gamma isoform 2 [Homo sapiens] [gi:20336229]
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17
[SID87344731]
Activator for delta FosB/delta FosB homodimer Measured in Biochemical System Using Plate Reader - 2072-01_Activator_SinglePoint_HTS_Activity [AID493131, Type: screening]protein fosB [Mus musculus] [gi:6679827]
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18
[SID87344731]
TRFRET-based biochemical primary high throughput screening assay to identify small molecules that bind to the HIV-1-gp120 binding antibody, PG9 [AID624416, Type: screening]Envelope surface glycoprotein gp160, precursor [Human immunodeficiency virus 1] [gi:9629363]
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19
[SID87344731]
TRFRET-based biochemical high throughput confirmation assay for small molecules that bind to the HIV-1-gp120 binding antibody, PG9 [AID651571, Type: screening]Envelope surface glycoprotein gp160, precursor [Human immunodeficiency virus 1] [gi:9629363]
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20
[SID87344731]
Counterscreen for discovery of small molecules that bind to the HIV-1-gp120 binding antibody, PG9: TR-FRET-based biochemical high throughput assay to identify small molecules that bind to the control antibody, PGV04, which binds to a site on the HIV envelope different from the PG9 binding site [AID651604, Type: screening]Envelope surface glycoprotein gp160, precursor [Human immunodeficiency virus 1] [gi:9629363]
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