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BioActivity Data for Compound N-(thiophen-2-ylmethyl)-4,5,6,7-tetrahydro-1,2-benzoxazole-3-carboxamide (CID 3241096)

BioActivity Outcomes:
Active(6)
 
 
Inactive(801)
 
 
Inconclusive(20)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(48)
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(9)
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(542)
 
 
 
 
Confirmatory(252)
 
 
 
 
 
Literature(11)
 
 
BioAssay Categories:
In vitro(2)
 
 
In vivo(1)
 
 
Biochemical(116)
 
 
Toxicity(13)
 
 
 
Cell-based(140)
 
 
 
 
Organism-base..(7)
 
 
BioActivity Types:
Potency(165)
 
 
 
 
 
IC50(50)
 
 
 
EC50(11)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 759    Data Row: 828   Total Pages: 42   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID4246801]
Potency 17.7828qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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2
[SID4246801]
Cell Proliferation & Viability (Cytotoxicity) Primary Assay 60K MLSMR [AID463, Type: screening]
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3
[SID4246801]
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID560, Type: screening]Nuclear receptor ROR-alpha [gi:548814]
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4
[SID4246801]
Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) [AID695, Type: confirmatory]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
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5
[SID4246801]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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6
[SID4246801]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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7
[SID4246801]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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8
[SID4246801]
Potency 0.0586Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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9
[SID4246801]
Potency 3.9811qHTS Assay for Compounds that Induce Erasure of Genomic Imprints [AID1948, Type: confirmatory]
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10
[SID4246801]
Potency 13.1154Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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11
[SID4246801]
Primary HTS assay for chemical inhibitors of antigen receptor-induced NF-kappaB activation [AID465, Type: screening]
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12
[SID4246801]
Ubiquitin-GFP Assay [AID526, Type: confirmatory]
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13
[SID4246801]
Primary HTS Assay for Inhibitors of Bacterial Quorum Sensing [AID527, Type: screening]
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14
[SID4246801]
Cell Proliferation & Viability (Cytotoxicity) Dose Response Assay 60K MLSMR [AID464, Type: confirmatory]
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15
[SID4246801]
IC50 A small molecule screen for inhibitors of the PhoP regulon in Salmonella typhi [AID1850, Type: confirmatory]
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16
[SID4246801]
Conc @ Max Fold Increase A high-throughput screen to identify small molecule compounds that augment HSV replication [AID1956, Type: confirmatory]
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17
[SID4246801]
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity [AID2099, Type: screening]
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18
[SID4246801]
Luminescence Cell-Based/Microorganism Primary HTS to Identify Inhibitors of T.Cruzi Replication [AID1885, Type: screening]
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19
[SID4246801]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Polyadenylation [AID1875, Type: screening]
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20
[SID4246801]
Luminescence Cell-Based Primary HTS to Identify Transcriptional Activators of Hypoxia-Inducible Factor Pathway [AID1910, Type: screening]
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