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SMR000023577 (CID 3241096) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(796)
 
 
Inconclusive(20)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(26)
 
 
7TM GPCR Srsx(21)
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(9)
 
 
BioAssay Types:
Screening(539)
 
 
 
 
Confirmatory(250)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(165)
 
 
 
 
 
IC50(48)
 
 
 
EC50(11)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 755    Data Row: 823   Total Pages: 42   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID4246801]
Potency 17.7828qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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2
[SID4246801]
Cell Proliferation & Viability (Cytotoxicity) Primary Assay 60K MLSMR [AID463, Type: screening]
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3
[SID4246801]
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) [AID560, Type: screening]Nuclear receptor ROR-alpha [gi:548814]
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4
[SID4246801]
Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) [AID695, Type: confirmatory]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
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5
[SID4246801]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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6
[SID4246801]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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7
[SID4246801]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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8
[SID4246801]
Potency 0.0586Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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9
[SID4246801]
Potency 3.9811qHTS Assay for Compounds that Induce Erasure of Genomic Imprints [AID1948, Type: confirmatory]
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10
[SID4246801]
Potency 13.1154Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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11
[SID4246801]
Homologous recombination - Rad 51 [AID1385, Type: screening]RAD51 [Homo sapiens] [gi:49168602]
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12
[SID4246801]
Luminescence Cell-Free Homogenous Primary HTS to Identify Inhibitors of GSK-3 alpha [AID2650, Type: screening]glycogen synthase kinase-3 alpha [Homo sapiens] [gi:49574532]
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13
[SID4246801]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. [AID1415, Type: screening]guanine nucleotide-binding protein G(o) subunit alpha isoform a [Homo sapiens] [gi:10567816]
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14
[SID4246801]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. [AID1423, Type: screening]guanine nucleotide-binding protein G(o) subunit alpha isoform a [Homo sapiens] [gi:10567816]
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15
[SID4246801]
HTS for Estrogen Receptor-beta Coactivator Binding inhibitors [AID633, Type: screening]estrogen receptor beta isoform 1 [Homo sapiens] [gi:10835013]
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16
[SID4246801]
qHTS for Inhibitors of Inflammasome Signaling: IL-1-beta AlphaLISA Primary Screen [AID743279, Type: screening]interleukin-1 beta proprotein [Homo sapiens] [gi:10835145]
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17
[SID4246801]
uHTS Colorimetric assay for identification of inhibitors of Scp-1 [AID493091, Type: screening]carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 [Homo sapiens] [gi:10864009]
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18
[SID4246801]
Luminescence-based cell-based primary high throughput screening assay to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) [AID624169, Type: screening]5-hydroxytryptamine receptor 2A [Mus musculus] [gi:27753985]
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19
[SID4246801]
uHTS for 14-3-3/Bad interaction inhibitors [AID781, Type: screening]14-3-3 protein zeta/delta [Bos taurus] [gi:27807367]
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20
[SID4246801]
IC50 High Throughput Fluorescence Polarization Screen for Bcl-B Phenotype Converters [AID748, Type: confirmatory]nuclear receptor subfamily 4 group A member 1 isoform 1 [Homo sapiens] [gi:27894344]
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