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[1-(2,1,3-benzothiadiazol-4-ylsulfonyl)piperidin-4-yl]-(1,2-dihydroimidazo[1,2-a]benzimidazol-3-yl)methanone (CID 3240530) - Compound BioActivity Data
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BioActivity Outcomes:
Active(29)
 
 
Inactive(754)
 
 
Inconclusive(15)
 
 
Unspecified(8)
 
 
Top Targets:
7tm 4(41)
 
 
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(10)
 
 
G-alpha(8)
 
 
BioAssay Types:
Screening(510)
 
 
 
Confirmatory(258)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(169)
 
 
 
 
 
IC50(58)
 
 
 
 
EC50(11)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 726    Data Row: 806   Total Pages: 41   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID4246149]
IC50_b-galactosidase (DX counterscreen)_Mean 0.239Dose response counterscreen for EBI2 assay utilizing the enzyme, b-galactosidase [AID652193, Type: confirmatory]Beta-galactosidase [gi:75404427]
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2
[SID4246149]
EC50 0.98HTS Dose response counterscreen for assays utilizing the enzyme, b-galactosidase [AID1966, Type: confirmatory]Beta-galactosidase [gi:75404427]
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3
[SID4246149]
Potency 6.5131qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504467, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
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4
[SID4246149]
Potency 16.3601qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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5
[SID4246149]
IC50_CXCR6_Mean Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_1, Type: confirmatory]apelin receptor [Homo sapiens] [gi:4885057]
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6
[SID4246149]
uHTS identification of small molecule antagonists of the APJ receptor via a luminescent beta-arrestin assay [AID2521, Type: screening]apelin receptor [Homo sapiens] [gi:4885057]
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7
[SID4246149]
Single concentration confirmation of uHTS hits from a small molecule antagonists of the APJ receptor via a luminescent beta-arrestin assay [AID2766, Type: screening]apelin receptor [Homo sapiens] [gi:4885057]
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8
[SID4246149]
uHTS identification of CXCR6 Inhibitors in a B-arrestin luminescence assay [AID602244, Type: screening]C-X-C chemokine receptor type 6 [Homo sapiens] [gi:5730106]
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9
[SID4246149]
IC50_CXCR6_Mean Dose Response confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor in a screening assay [AID624129_7, Type: confirmatory]C-X-C chemokine receptor type 6 [Homo sapiens] [gi:5730106]
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10
[SID4246149]
Single concentration confirmation of uHTS hits from a small molecule antagonists of the CXCR6 receptor via a luminescent beta-arrestin assay [AID602409, Type: screening]C-X-C chemokine receptor type 6 [Homo sapiens] [gi:5730106]
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11
[SID4246149]
Single concentration validation of small molecule antagonists of the EBI2 receptor via a luminescent beta-galactosidase assay [AID652176, Type: screening]Beta-galactosidase [gi:75404427]
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12
[SID4246149]
qHTS of D3 Dopamine Receptor Antagonist: qHTS [AID652054, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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13
[SID4246149]
Cytochrome panel assay with activity outcomes [AID1851_3, Type: other]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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14
[SID4246149]
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 1 (CHRM1) [AID588814, Type: screening]muscarinic acetylcholine receptor M1 [Homo sapiens] [gi:37622910]
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15
[SID4246149]
uHTS identification of small molecule antagonists of the EBI2 receptor via a luminescent beta-arrestin assay [AID651636, Type: screening]G-protein coupled receptor 183 [Homo sapiens] [gi:4826706]
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16
[SID4246149]
Single concentration confirmation of uHTS hits from a small molecule antagonists of the EBI2 receptor via a luminescent beta-arrestin assay [AID651997, Type: screening]G-protein coupled receptor 183 [Homo sapiens] [gi:4826706]
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17
[SID4246149]
qHTS Assay for Spectroscopic Profiling in 4-MU Spectral Region [AID589, Type: other]
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18
[SID4246149]
qHTS Assay for Spectroscopic Profiling in A350 Spectral Region [AID590, Type: other]
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19
[SID4246149]
Cytochrome panel assay with activity outcomes [AID1851_1, Type: other]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
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20
[SID4246149]
Counterscreen for inverse agonists of OPRM1-OPRD1 heterodimerization: luminescence-based cell-based full-deck high throughput screening assay to identify inverse agonists of 5-hydroxytryptamine (serotonin) 5A receptor (HTR5A) [AID504634, Type: screening]5-hydroxytryptamine receptor 5A [Homo sapiens] [gi:13236497]
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