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ST50677555 (CID 3236902) - Compound BioActivity Data
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BioActivity Outcomes:
Active(20)
 
 
Inactive(797)
 
 
Inconclusive(40)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(26)
 
 
 
7TM GPCR Srsx(21)
 
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(10)
 
 
 
BioAssay Types:
Screening(568)
 
 
 
 
 
Confirmatory(261)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(170)
 
 
 
 
 
IC50(53)
 
 
 
EC50(15)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 791    Data Row: 859   Total Pages: 18   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID4241990]
Potency 13.1154Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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2
[SID4241990]
Potency 14.581Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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3
[SID4241990]
Potency 18.3564qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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4
[SID4241990]
Potency 23.1093qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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5
[SID4241990]
IC50 mean 33.0239Cathepsin G dose-response confirmation [AID832, Type: confirmatory]Cathepsin G [Homo sapiens] [gi:15680217]
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6
[SID4241990]
EC50 50A cytotoxicity screen of small molecule inhibitors of the PhoP regulon in Salmonella typhimurium identified in the primary screen [AID2253, Type: confirmatory]
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7
[SID4241990]
Chemical Genetic Screen to Identify Inhibitors of Mitochondrial Fusion - Primary Screen [AID1362, Type: screening]
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8
[SID4241990]
Screening for Modulators of Post-Golgi Transport, Control Strain [AID738, Type: screening]
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9
[SID4241990]
Luminescence-based cell-based high throughput confirmation assay for activators of the GAA850 frataxin (FXN) promoter [AID588351, Type: screening] [geneid:2395]
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10
[SID4241990]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the GAA850 frataxin (FXN) promoter [AID540364, Type: screening] [geneid:2395]
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11
[SID4241990]
Cell signaling CRE-BLA (Fsk stim) [AID662, Type: confirmatory]
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12
[SID4241990]
Factor XIa Mixture HTS [AID680, Type: screening]coagulation factor XI [Homo sapiens] [gi:180352]
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13
[SID4241990]
Antagonist of Human D 1 Dopamine Receptor: qHTS [AID504652, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
View
14
[SID4241990]
Counterscreen for PME1 inhibitors: fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of lysophospholipase 2 (LYPLA2). [AID2177, Type: screening]lysophospholipase II [Homo sapiens] [gi:4581413]
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15
[SID4241990]
Counterscreen for PME1 inhibitors: fluorescence polarization-based biochemical high throughput confirmation assay to identify inhibitors of lysophospholipase 2 (LYPLA2). [AID2232, Type: screening]lysophospholipase II [Homo sapiens] [gi:4581413]
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16
[SID92709238]
Late stage assay provider results from the probe development effort to identify selective inhibitors of LYPLA2: Fluorescence-based biochemical gel-based ABPP inhibition [AID652029, Type: other]acyl-protein thioesterase 2 [Homo sapiens] [gi:9966764]
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17
[SID4241990]
Cathepsin G [AID581, Type: screening]Cathepsin G [Homo sapiens] [gi:15680217]
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18
[SID4241990]
qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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19
[SID4241990]
qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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20
[SID4241990]
uHTS identification of small molecule inhibitors of tim10-1 yeast via a luminescent assay [AID463190, Type: screening]TPA: Tim10p [Saccharomyces cerevisiae S288c] [gi:285809906]
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21
[SID4241990]
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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22
[SID4241990]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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23
[SID4241990]
Potency 5.0119qHTS Assay for Compounds that Induce Erasure of Genomic Imprints [AID1948, Type: confirmatory]
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24
[SID4241990]
Potency 25.1189qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588456, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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25
[SID4241990]
Potency 28.1838qHTS Inhibitors of AmpC Beta-Lactamase (assay without detergent) [AID485341, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
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26
[SID4241990]
Potency 31.6228qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588453, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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27
[SID4241990]
EC50 59.62Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter [AID588504, Type: confirmatory] [geneid:2395]
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28
[SID4241990]
EC50 59.62Counterscreen for activators of the GAA850 frataxin promoter: luminescence-based cell-based high throughput dose response assay to identify activators of the GAA30 frataxin promoter [AID588505, Type: confirmatory] [geneid:2395]
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29
[SID4241990]
Small Molecules that selectively kill Giardia lamblia: qHTS [AID540267, Type: screening]
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30
[SID4241990]
Counterscreen for activators of the GAA850 frataxin promoter: luminescence-based cell-based high throughput screening assay to identify activators of the GAA30 frataxin promoter [AID588350, Type: screening] [geneid:2395]
View
31
[SID4241990]
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID493008, Type: screening]cardiac alpha tropomyosin [Sus scrofa] [gi:1927]
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32
[SID4241990]
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID493244, Type: screening]cardiac alpha tropomyosin [Sus scrofa] [gi:1927]
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33
[SID4241990]
uHTS identification of agonists of the CRF-binding protein and CRF-R2 receptor complex [AID588473, Type: screening]corticotropin releasing factor-binding protein [Homo sapiens] [gi:30219]
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34
[SID4241990]
uHTS identification of antagonists of the CRF-binding protein and CRF-R2 receptor complex [AID588475, Type: screening]corticotropin releasing factor-binding protein [Homo sapiens] [gi:30219]
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35
[SID4241990]
Primary Cell Based High Throughput Screening Assay for Antagonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) [AID571, Type: screening]5-hydroxytryptamine receptor 1E [gi:112822]
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36
[SID4241990]
Primary Cell Based High Throughput Screening Assay for Agonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) [AID574, Type: screening]5-hydroxytryptamine receptor 1E [gi:112822]
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37
[SID4241990]
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Antagonist Primary Screen [AID628, Type: screening]Muscarinic acetylcholine receptor M1 [gi:113121]
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38
[SID4241990]
Potency qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy [AID624291, Type: confirmatory]Glycoprotein hormones alpha chain [gi:121312]
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39
[SID4241990]
RNA polymerase [AID559, Type: screening]RNA polymerase beta subunit (EC 2.7.7.6), partial [Escherichia coli] [gi:147728]
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40
[SID4241990]
Counter Screen for Glucose-6-Phosphate Dehydrogenase-based Primary Assay [AID1020, Type: screening]glucose-6-phosphate dehydrogenase [Leuconostoc mesenteroides] [gi:149631]
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41
[SID4241990]
Potency qHTS Assay for Inhibitors of Firefly Luciferase [AID411, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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42
[SID4241990]
Potency qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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43
[SID4241990]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype [AID758, Type: screening]GTP-binding protein (rab7) [Canis lupus familiaris] [gi:164058]
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44
[SID4241990]
Potency Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS [AID504937, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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45
[SID4241990]
Modulators of Post-Golgi Transport [AID739, Type: screening]
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46
[SID4241990]
Inhibitors of Highly Pathogenic Avian Influenza (H5N1) Infection [AID740, Type: screening]
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47
[SID4241990]
Luminescent HTS for small molecule activators of MT1-MMP transcription [AID750, Type: screening]
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48
[SID4241990]
Disassembly of the 26S Proteasome (ATP Hydrolysis-dependent) [AID751, Type: screening]
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49
[SID4241990]
Isolation of Inhibitors of Her-Kinase Expression - 66K library screen [AID645, Type: screening]
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50
[SID4241990]
Human Endothelial Cell Proliferation Assay in 384-well format [AID648, Type: screening]
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