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BioActivity Data for Compound 2-(3-methoxyphenyl)-4-(4-methylpiperazin-1-yl)quinazoline (CID 3235287)

BioActivity Outcomes:
Active(7)
 
 
Inactive(80)
 
 
Inconclusive(12)
 
 
Unspecified(2)
 
 
Top Targets:
p450(9)
 
 
 
HSD10-like SD..(4)
 
 
PKc CLK1 4(3)
 
 
 
 
ampC(2)
 
 
Peptidase C1A(2)
 
 
BioAssay Types:
Confirmatory(87)
 
 
 
 
 
Screening(1)
 
 
BioAssay Categories:
Toxicity(2)
 
 
BioActivity Types:
Potency(61)
 
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 90    Data Row: 101   Total Pages: 6   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID4240181]
Potency 7.9433qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6 [AID891, Type: confirmatory]cytochrome P450 2D6 isoform 1 [Homo sapiens] [gi:40805836]
View
2
[SID4240181]
Potency 15.8489qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
3
[SID4240181]
Potency 28.1838qHTS Assay for Inhibitors of CDC-like Kinase 4 (Kinase-Glo Assay) [AID1770, Type: confirmatory]dual specificity protein kinase CLK4 [Homo sapiens] [gi:10190706]
View
4
[SID4240181]
Cytochrome panel assay with activity outcomes [AID1851_3, Type: other]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
5
[SID4240181]
Cytochrome panel assay with activity outcomes [AID1851_2, Type: other]cytochrome P450 2D6 isoform 2 [Homo sapiens] [gi:68509921]
View
6
[SID4240181]
p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450 1A2 [Homo sapiens] [gi:73915100]
View
7
[SID4240181]
Cytochrome panel assay with activity outcomes [AID1851_4, Type: other]cytochrome P450 1A2 [Homo sapiens] [gi:73915100]
View
8
[SID4240181]
Potency 7.9433qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor [AID926, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
9
[SID4240181]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
View
10
[SID4240181]
Potency 12.5893qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a [AID927, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
View
11
[SID4240181]
Potency 15.8489qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
12
[SID4240181]
Potency qHTS Assay for Inhibitors of CDC-like Kinase 4 (ADP-FP Assay) [AID1795, Type: confirmatory]dual specificity protein kinase CLK4 [Homo sapiens] [gi:10190706]
View
13
[SID4240181]
Potency qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
View
14
[SID4240181]
Cytochrome panel assay with activity outcomes [AID1851_5, Type: other]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
View
15
[SID4240181]
Potency qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9 [AID883, Type: confirmatory]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
View
16
[SID4240181]
Potency qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1 [AID900, Type: confirmatory]caspase-1 isoform alpha precursor [Homo sapiens] [gi:15431328]
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17
[SID4240181]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide [AID1766, Type: confirmatory]menin isoform 1 [Homo sapiens] [gi:18860839]
View
18
[SID4240181]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]menin isoform 1 [Homo sapiens] [gi:18860839]
View
19
[SID4240181]
Potency qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
20
[SID4240181]
Potency qHTS Assay for Modulators of Lamin A Splicing [AID1487, Type: confirmatory]lamin isoform A-delta10 [Homo sapiens] [gi:27436948]
View