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BioActivity Data for Compound 2-(2,4-dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-(4-ethoxyphenyl)acetamide (CID 3153587)

BioActivity Outcomes:
Active(19)
 
 
Inactive(661)
 
 
Inconclusive(27)
 
 
Unspecified(10)
 
 
Top Targets:
7tm 4(41)
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
ZnMc TACE lik..(8)
 
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(477)
 
 
 
 
Confirmatory(212)
 
 
 
 
 
Literature(11)
 
 
BioAssay Categories:
In vivo(1)
 
 
Biochemical(140)
 
 
 
 
Toxicity(5)
 
 
Cell-based(136)
 
 
Organism-base..(11)
 
 
BioActivity Types:
Potency(145)
 
 
 
 
 
IC50(53)
 
 
 
 
 
EC50(7)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 643    Data Row: 717   Total Pages: 36   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24780541]
Potency 1.1582qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID24780541]
Potency 2.9093qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID24780541]
IC50 5.733QFRET-based biochemical high throughput dose response assay to identify exosite inhibitors of ADAM17 [AID743260, Type: confirmatory]disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] [gi:73747889]
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4
[SID172232638]
IC50 7.835Late stage QFRET-based biochemical high throughput dose response assay to identify exosite inhibitors of ADAM17 [AID743337, Type: confirmatory]disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] [gi:73747889]
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5
[SID24780541]
Potency 7.9433qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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6
[SID24780541]
Potency 9.4662qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
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7
[SID24780541]
Potency 10qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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8
[SID24780541]
Potency 19.8003qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen [AID2100, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
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9
[SID24780541]
Potency 28.1838Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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10
[SID24780541]
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3) [AID1800, Type: screening]NS3, partial [Hepatitis C virus] [gi:125541954]
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11
[SID24780541]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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12
[SID24780541]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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13
[SID24780541]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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14
[SID24780541]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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15
[SID24780541]
Fluorescence Cell-Free Homogeneous Primary HTS to Identify Inhibitors of Histone Deacetylase 3 [AID2718, Type: screening]histone deacetylase 3 [Homo sapiens] [gi:13128862]
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16
[SID172232638]
Late stage assay provider QFRET-based biochemical high throughput dose response assay to counterscreen inhibitors of ADAM10 and ADAM17 against metalloproteases MMP1, MMP2, MMP8, MMP9, MMP10, MMP13, MMP14, Meprin A, and Meprin B [AID743473, Type: confirmatory]
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17
[SID24780541]
QFRET-based biochemical high throughput confirmation assay to identify exosite inhibitors of ADAM17 [AID743257, Type: screening]disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] [gi:73747889]
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18
[SID24780541]
QFRET-based biochemical primary high throughput screening assay to identify exosite inhibitors of ADAM17. [AID720648, Type: screening]disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] [gi:73747889]
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19
[SID24780541]
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1). [AID720700, Type: screening]Phospholipase C, gamma 1 [Homo sapiens] [gi:223459640]
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20
[SID172232638]
IC50 {MMP8} 1.6Late stage assay provider QFRET-based biochemical high throughput dose response assay to counterscreen inhibitors of ADAM10 and ADAM17 against metalloproteases MMP1, MMP2, MMP8, MMP9, MMP10, MMP13, MMP14, Meprin A, and Meprin B [AID743473_3, Type: confirmatory]matrix metallopeptidase 8 (neutrophil collagenase) [Homo sapiens] [gi:119587431]
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