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BioActivity Data for Compound dimethylacetamide (CID 31374)

BioActivity Outcomes:
Active(10)
 
 
Inactive(253)
 
 
Inconclusive(16)
 
 
Unspecified(6)
 
 
Top Targets:
NR LBD PPAR(16)
 
 
NR LBD ER(14)
 
 
NR LBD AR(14)
 
 
NR LBD VDR(9)
 
 
NR LBD TR(8)
 
 
 
BioAssay Types:
Confirmatory(179)
 
 
 
 
Summary(52)
 
 
 
Literature(6)
 
 
Screening(5)
 
 
 
BioAssay Categories:
In vivo(31)
 
 
 
 
Toxicity(12)
 
 
 
ADME(1)
 
 
Cell-based(4)
 
 
BioActivity Types:
Potency(216)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 186    Data Row: 285   Total Pages: 15   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144213104]
Potency-Replicate_1 68.5896qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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2
[SID29215334]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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3
[SID29215334]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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4
[SID29215334]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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5
[SID29215334]
A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 B subunit [Escherichia coli O157:H7] [gi:32400300]
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6
[SID69667]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia resistant to Methyl-GAG; NSC 32946 (subcutaneous) in B6D2F1 (BDF1) mice [AID306, Type: other]
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7
[SID69667]
NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID328, Type: other]
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8
[SID69667]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Leiomyosarcoma (No. 2) (intraperitoneal) in CAF1 mice [AID238, Type: other]
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9
[SID69667]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Adenocarcinoma 755 (subcutaneous) in B6D2F1 (BDF1) mice [AID180, Type: other]
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10
[SID48415903]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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11
[SID103173123]
Aqueous solubility [AID19262, Type: Literature]
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12
[SID103173123]
Second-order rate constant (M-1 s-1) for the alkaline hydrolysis in water at 30 degrees C [AID28486, Type: Literature]
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13
[SID103173123]
Percentage of benzidine-positive murine erythroleukemia cells on day 6. [AID70688, Type: Literature]
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14
[SID103173123]
Cell growth was measured on day 3, after murine erythroleukemia cells were exposed at a cell concentration of 1*10e5 cells/mL. [AID70689, Type: Literature]
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15
[SID103173123]
Cell growth was measured on day 6 after murine erythroleukemia cells were exposed at a cell concentration of 1*10e5 cells/mL. [AID70690, Type: Literature]
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16
[SID103173123]
Concentration producing the maximum percentage of benzidine-positive cells after 6-days of continuous exposure in murine leukemia cells. [AID70691, Type: Literature]
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17
[SID144209372]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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18
[SID29215334]
Potency qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia [AID1477, Type: confirmatory]
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19
[SID29215334]
Potency Quantitative High-Throughput Screen for Regulators of Epigenetic Control [AID1865, Type: confirmatory]
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20
[SID29215334]
Potency qHTS Assay for Compounds that Induce Erasure of Genomic Imprints [AID1948, Type: confirmatory]
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