Bookmark and Share
pyrrolidine (CID 31268) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(1)
 
 
Inactive(6)
 
 
Unspecified(7)
 
 
Top Targets:
Aa trans(1)
 
 
BioAssay Types:
Literature(10)
 
 
 
 
BioActivity Types:
Kd(1)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 14    Data Row: 14   Total Pages: 1   
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103189394]
Kd 25Ability to enhance the binding of (+/-)-[3H]nicotine to the rat brain P2 fraction at binding site 2 [AID30389, Type: Literature]
View
2
[SID103189394]
Ki 38000Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting [AID630741, Type: Literature]Proton-coupled amino acid transporter 1 [gi:51316800]
View
3
[SID103189394]
Maximum percent of enhancement of binding. [AID30377, Type: Literature]
View
4
[SID103189394]
Maximum percent of inhibition of binding was determined [AID30378, Type: Literature]
View
5
[SID103189394]
Compound was evaluated for ability to enhance the binding of (+/-)-[3H]nicotine to the rat brain P2 fraction at binding site 1; 10e-10-10e-6 [AID30382, Type: Literature]
View
6
[SID103189394]
Dissociation constant, pKa of the compound [AID701844, Type: Literature]
View
7
[SID103189394]
pKa (acid-base dissociation constant) as determined by Morgenthaler ref: ChemMedChem 2007 [AID781327, Type: Literature]
View
8
[SID103189394]
Compounds was evaluate for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 10 E -10 - 10 E -6 M was reported [AID30521, Type: Literature]
View
9
[SID103189394]
Hydrogen peroxide release activity in potassium phosphate buffer at pH 7.4 after 60 mins by xylene-orange based colorimetric assay [AID661627, Type: Literature]
View
10
[SID103189394]
Superoxide release activity in potassium phosphate buffer at pH 7.4 and 25 uM after 30 mins by luminol-based colorimetric assay [AID661629, Type: Literature]
View
11
[SID109780]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID248, Type: other]
View
12
[SID109780]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Lewis Lung Carcinoma (subcutaneous) in B6D2F1 (BDF1) mice [AID270, Type: other]
View
13
[SID109780]
NCI In Vivo Anticancer Drug Screen. Data for tumor model P1534 Leukemia (intraperitoneal) in DBA/2 mice [AID314, Type: other]
View
14
[SID109780]
NCI In Vivo Anticancer Drug Screen. Data for tumor model P1534 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice [AID316, Type: other]
View