chloride (CID 312) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(4)
 
 
Unspecified(11)
 
 
Top Targets:
alpha CA I II..(6)
 
 
 
alpha CA IV X..(2)
 
 
LbH gamma CA(1)
 
 
alpha CA(1)
 
 
alpha CA VII(1)
 
 
BioAssay Types:
Literature(15)
 
 
 
BioActivity Types:
Ki(15)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 15    Data Row: 15   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103450290]
Ki 0.006Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coli [AID238687, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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2
[SID103450290]
Ki 0.138Inhibitory activity against mouse carbonic anhydrase XIII expressed in Escherichia coli TOP 10 [AID238853, Type: Literature]
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3
[SID103450290]
Ki 0.156Inhibitory activity against human carbonic anhydrase V expressed in Escherichia coli [AID238688, Type: Literature]
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4
[SID103450290]
Ki 0.2Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coli [AID238715, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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5
[SID103450290]
Ki 90Inhibition constant of anion against human carbonic anhydrase isozyme hCA IV [AID238544, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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6
[SID103450290]
Ki 1840Inhibition of human recombinant CA7 [AID265737, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
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7
[SID103450290]
Ki 6000Inhibitory constant against carbonic anhydrase I [AID238317, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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8
[SID103450290]
Ki 6000Inhibition constant of anion against human carbonic anhydrase isozyme hCA I [AID238513, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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9
[SID103450290]
Ki 33000Inhibition constant of anion against human carbonic anhydrase isozyme hCA IX [AID238546, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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10
[SID103450290]
Ki 36000Inhibitory constant against carbonic anhydrase IV [AID238328, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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11
[SID103450290]
Ki 152000Inhibitory constant against methanoarchaeon Methanobacterium thermoautotrophicum (Cab) [AID238896, Type: Literature]
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12
[SID103450290]
Ki 156000Inhibition constant of anion against human carbonic anhydrase isozyme hCA V [AID238515, Type: Literature]
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13
[SID103450290]
Ki 200000Inhibitory constant against Zn-Cam (Methanosarcina thermophila) [AID238607, Type: Literature]Carbonic anhydrase [gi:729004]
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14
[SID103450290]
Ki 200000Inhibitory constant against carbonic anhydrase II [AID238327, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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15
[SID103450290]
Ki 200000Inhibition constant of anion against human carbonic anhydrase isozyme hCA II [AID238542, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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