8-Nitro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid (CID 3112185) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(12)
 
 
Inactive(6)
 
 
Top Targets:
DSPc(5)
 
 
PTPc(3)
 
 
14-3-3 gamma(1)
 
 
Gp dh C(1)
 
 
HSPA1-2 6-8-l..(1)
 
 
BioAssay Types:
Confirmatory(11)
 
 
Screening(7)
 
 
 
BioActivity Types:
IC50(11)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 18    Data Row: 18   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26513840]
IC50 6.06In Vitro Hsp70 Dose Response Fluorescence Polarization Assay for SAR Study [AID1072, Type: confirmatory]heat shock 70kDa protein 1A [Homo sapiens] [gi:123271505]
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2
[SID26513840]
IC50 7.58In Vitro HePTP Dose Response Colorimetric Assay for SAR Study [AID1059, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
View
3
[SID26513840]
IC50 7.58In Vitro HePTP Dose Response Colorimetric Assay for SAR Study [AID1059, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
View
4
[SID26513840]
IC50 7.58In Vitro HePTP Dose Response Colorimetric Assay for SAR Study [AID1059, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
View
5
[SID26513840]
IC50 16.6Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP [AID1077, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
View
6
[SID26513840]
IC50 16.6Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP [AID1077, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
View
7
[SID26513840]
IC50 16.6Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP [AID1077, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
View
8
[SID26513840]
IC50 47.47MKP-3 in vitro secondary assay for identification of redox-state modulating compounds [AID1054, Type: confirmatory]dual specificity protein phosphatase 6 [Rattus norvegicus] [gi:16758752]
View
9
[SID26513840]
IC50 47.47MKP-3 in vitro secondary assay for identification of redox-state modulating compounds [AID1054, Type: confirmatory]dual specificity protein phosphatase 6 [Rattus norvegicus] [gi:16758752]
View
10
[SID26513840]
IC50 47.47In Vitro MKP-3 Dose Response Assay for SAR Study [AID1055, Type: confirmatory]dual specificity protein phosphatase 6 [Rattus norvegicus] [gi:16758752]
View
11
[SID26513840]
IC50 47.47In Vitro MKP-3 Dose Response Assay for SAR Study [AID1055, Type: confirmatory]dual specificity protein phosphatase 6 [Rattus norvegicus] [gi:16758752]
View
12
[SID26513840]
IC50 48.4In Vitro Hsc70 Dose Response Fluorescence Polarization Assay [AID1193, Type: confirmatory]heat shock cognate 71 kDa protein isoform 1 [Homo sapiens] [gi:5729877]
View
13
[SID26513840]
IC50 48.4In Vitro Hsc70 Dose Response Fluorescence Polarization Assay [AID1193, Type: confirmatory]heat shock cognate 71 kDa protein isoform 1 [Homo sapiens] [gi:5729877]
View
14
[SID26513840]
IC50 48.4In Vitro Hsc70 Dose Response Fluorescence Polarization Assay [AID1193, Type: confirmatory]heat shock cognate 71 kDa protein isoform 1 [Homo sapiens] [gi:5729877]
View
15
[SID26513840]
IC50 52MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors [AID1052, Type: confirmatory]dual specificity protein phosphatase 6 [Rattus norvegicus] [gi:16758752]
View
16
[SID26513840]
IC50 52MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors [AID1052, Type: confirmatory]dual specificity protein phosphatase 6 [Rattus norvegicus] [gi:16758752]
View
17
[SID26513840]
IC50 97.4GAPDH Dose Response Colorimetric Assay [AID1227, Type: confirmatory]glyceraldehyde-3-phosphate dehydrogenase [Homo sapiens] [gi:7669492]
View
18
[SID26513840]
IC50 97.4GAPDH Dose Response Colorimetric Assay [AID1227, Type: confirmatory]glyceraldehyde-3-phosphate dehydrogenase [Homo sapiens] [gi:7669492]
View
19
[SID17450675]
 HTS Colorimetric assay for the identification of compounds that inhibit VHR1 [AID1992, Type: screening]dual specificity protein phosphatase 3 [Homo sapiens] [gi:4758208]
View
20
[SID17450675]
 HTS Colorimetric assay for the identification of compounds that inhibit VHR1 [AID1992, Type: screening]dual specificity protein phosphatase 3 [Homo sapiens] [gi:4758208]
View
21
[SID17450675]
IC50 High Throughput Screening Assay for Hsp70 Inhibitors [AID583, Type: confirmatory]heat shock 70kDa protein 1A [Homo sapiens] [gi:123271505]
View
22
[SID17450675]
IC50 HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target [AID521, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
View
23
[SID17450675]
IC50 HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target [AID521, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
View
24
[SID17450675]
IC50 HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target [AID521, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
View
25
[SID17450675]
IC50 MKP-3 in vitro HTS assay [AID425, Type: confirmatory]dual specificity protein phosphatase 6 [Rattus norvegicus] [gi:16758752]
View
26
[SID17450675]
IC50 MKP-3 in vitro HTS assay [AID425, Type: confirmatory]dual specificity protein phosphatase 6 [Rattus norvegicus] [gi:16758752]
View
27
[SID7996054]
 Formylpeptide Receptor Ligand Binding Assay [AID362, Type: screening]formyl peptide receptor 1 [Homo sapiens] [gi:4503779]
View
28
[SID7996054]
 Formylpeptide Receptor Ligand Binding Assay [AID362, Type: screening]formyl peptide receptor 1 [Homo sapiens] [gi:4503779]
View
29
[SID17450675]
 High Throughput Screen for Inhibitors of ER Stress-induced Cell Death [AID1010, Type: screening]
View
30
[SID24294537]
 Non-Nucleoside Inhibitor of Measles Virus RNA-Dependent RNA Polymerase Complex Activity HTS Single Point [AID745, Type: screening]
View
31
[SID8080698]
 HIV-1 RNase H Inhibition [AID372, Type: screening]Chain A, Solution Structure Of The Rnase H Domain Of The Hiv-1 Reverse Transcriptase In The Presence [gi:28949057]
View
32
[SID24294537]
 HTS for 14-3-3 protein interaction modulators [AID422, Type: screening]tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide [Homo sapi [gi:21464101]
View
33
[SID24294537]
 HTS for BAP1 Enzyme inhibitors [AID436, Type: screening]Ubiquitin carboxyl-terminal hydrolase BAP1 (BRCA1-associated protein 1) (Cerebral protein 6) [gi:68565074]
View