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2-nitro-N-[4-[6-[(2-nitrobenzoyl)amino]-1H-benzimidazol-2-yl]phenyl]benzamide (CID 3106750) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(12)
 
 
Top Targets:
CD36(3)
 
 
 
DSPc(2)
 
 
PTPc(1)
 
 
Peptidase S29(1)
 
 
RNase H(1)
 
 
BioAssay Types:
Confirmatory(8)
 
 
 
Screening(6)
 
 
BioActivity Types:
AC50(5)
 
 
 
IC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 14    Data Row: 14   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID118045973]
AC50_uM 0.0549HDL Orthogonal Assay: Alexa 488-HDL Measured in Cell-Based System Using Plate Reader - 2085-03_Inhibitor_Dose_DryPowder_Activity [AID588777, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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2
[SID118045973]
AC50_uM 0.251HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity [AID540354, Type: confirmatory]
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3
[SID118045973]
AC50_uM HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-02_Inhibitor_Dose_DryPowder_Activity_Set5 [AID602126, Type: confirmatory]
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4
[SID163601494]
Fluorescence-based counterscreen assay for HCV NS3 helicase inhibitors of a ChemBridge library: biochemical high-throughput screening assay to identify compounds that enhance or quench Cy5 fluorescence [AID720488, Type: screening]
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5
[SID17437636]
Fluorescence Polarization Screen Assay for Bcl-B Phenotype Converters [AID1240, Type: screening]nuclear receptor subfamily 4 group A member 1 isoform 1 [Homo sapiens] [gi:27894344]
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6
[SID17437636]
High Throughput Screen for Inhibitors of ER Stress-induced Cell Death [AID1010, Type: screening]
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7
[SID118045973]
AC50_uM HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-11_Inhibitor_Dose_DryPowder_Activity [AID588830, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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8
[SID17437636]
IC50 MKP-3 in vitro HTS assay [AID425, Type: confirmatory]dual specificity protein phosphatase 6 [Rattus norvegicus] [gi:16758752]
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9
[SID8062670]
HIV-1 RNase H Inhibition [AID372, Type: screening]Chain A, Solution Structure Of The Rnase H Domain Of The Hiv-1 Reverse Transcriptase In The Presence Of Magnesium [gi:28949057]
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10
[SID118045973]
AC50_uM HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-02_Inhibitor_Dose_DryPowder_Activity [AID540246, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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11
[SID17437636]
HTS Colorimetric assay for the identification of compounds that inhibit VHR1 [AID1992, Type: screening]dual specificity protein phosphatase 3 [Homo sapiens] [gi:4758208]
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12
[SID163601494]
Fluorescence polarization based primary biochemical high throughput screening assay of ChemBridge compounds to identify inhibitors of hepatitis C virus non-structural protein 3 helicase [AID687043, Type: screening]NS3, partial [Hepatitis C virus] [gi:125541954]
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13
[SID17437636]
IC50 High Throughput Screening Assay for Hsp70 Inhibitors [AID583, Type: confirmatory]heat shock 70kDa protein 1A [Homo sapiens] [gi:123271505]
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14
[SID17437636]
IC50 HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target [AID521, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
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