benzophenone (CID 3102) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(5)
 
 
Inactive(600)
 
 
Inconclusive(7)
 
 
Unspecified(23)
 
 
Top Targets:
7TM GPCR Srx(15)
 
 
NR LBD TR(10)
 
 
 
NR LBD PPAR(10)
 
 
 
Peptidase C1A(7)
 
 
 
7TM GPCR Srsx(6)
 
 
BioAssay Types:
Confirmatory(303)
 
 
 
 
 
Screening(268)
 
 
 
Literature(33)
 
 
 
 
 
BioActivity Types:
Potency(254)
 
 
 
 
 
IC50(15)
 
 
 
 
Ki(5)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 557    Data Row: 635   Total Pages: 13   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389587]
Potency 25.1189qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
View
2
[SID17389587]
Potency 25.1189qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
View
3
[SID46391755]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Porcine Odorant Binding Protein Complexed With Diphenylmethanone [gi:12084615]
View
4
[SID48415153]
 DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
View
5
[SID49816673]
 uHTS Fluorescent Assay Using Nedd8 Protein Substrate for Identification of Inhibitors of Sentrin-Specific Protease 8 (SENP8) [AID602440, Type: screening]SENP8 gene product [Homo sapiens] [gi:262118306]
View
6
[SID103300986]
 Inhibition of apolipoprotein E production in human CCF-STTG1 cells at 10 uM after 24 hrs by ELISA relative to vehicle-treated control [AID684467, Type: Literature]
View
7
[SID103300986]
Ki 100Inhibition constant against human intestinal carboxylesterase 2 (hiCE) using nitrophenyl acetate (o-NPA) as substrate [AID239272, Type: Literature]Cocaine esterase [gi:46576349]
View
8
[SID103300986]
Ki 100Inhibition constant against human Butyrylcholinesterase (hBuChE) using butyrylthiocholine (BuTCh) as substrate [AID239166, Type: Literature]Cholinesterase [gi:116353]
View
9
[SID103300986]
Ki 100Inhibition constant against rabbit liver carboxylesterase (rCE) using nitrophenyl acetate (o-NPA) as substrate [AID239167, Type: Literature]
View
10
[SID103300986]
Ki 100Inhibition constant against human liver carboxylesterase 1 (hCE1) using nitrophenyl acetate (o-NPA) as substrate [AID239197, Type: Literature]Liver carboxylesterase 1 [gi:119576]
View
11
[SID103300986]
Ki 100Inhibition constant against human liver carboxylesterase 1 (hCE1) using nitrophenyl acetate (o-NPA) as substrate [AID239197, Type: Literature]Liver carboxylesterase 1 [gi:119576]
View
12
[SID103300986]
Ki 100Inhibition constant against human Acetylcholinesterase (hAcChE) using acetylthiocholine (AcTCh) as substrate [AID239122, Type: Literature]Acetylcholinesterase [gi:113037]
View
13
[SID103300986]
IC50 128.825Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881) [AID255211, Type: Literature]
View
14
[SID103300986]
IC50 288.8Inhibition of cathepsin B by spectrofluorimetry [AID351454, Type: Literature]
View
15
[SID103300986]
IC50 1000Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AI [AID443993, Type: Literature]Indoleamine 2,3-dioxygenase 1 [gi:123948]
View
16
[SID103300986]
IC50 3465Inhibition of Carica papaya papain by spectrofluorimetry [AID351452, Type: Literature]Papain [gi:129614]
View
17
[SID103300986]
IC50 3466Inhibition of trypsin by spectrofluorimetry [AID351453, Type: Literature]
View
18
[SID49816673]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
19
[SID49816673]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
20
[SID26752803]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
21
[SID26752802]
 qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP) [AID1471, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
View
22
[SID26752802]
 qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP) [AID1471, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
View
23
[SID103300986]
 logD (measured by HPLC) (as log k') [AID23959, Type: Literature]
View
24
[SID103300986]
 logD (measured by HPLC) (as log k') [AID23960, Type: Literature]
View
25
[SID103300986]
 logD (measured by HPLC) (as log k') [AID23963, Type: Literature]
View
26
[SID103300986]
 logD (measured by HPLC) (as log k') [AID23965, Type: Literature]
View
27
[SID103300986]
 logD (measured by HPLC) (as log k') [AID23968, Type: Literature]
View
28
[SID103300986]
 logD (measured by HPLC) (as log k') [AID23970, Type: Literature]
View
29
[SID103300986]
 logD (measured by HPLC) (as log k') [AID23971, Type: Literature]
View
30
[SID103300986]
 Partition coefficient (logD, measured by HPLC, log k') [AID23973, Type: Literature]
View
31
[SID103300986]
 Partition coefficient (logD7.4) [AID26296, Type: Literature]
View
32
[SID17389587]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
33
[SID49816673]
Potency 12.5893qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
View
34
[SID49816673]
Potency 50.1187qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS [AID624287, Type: confirmatory]Guanine nucleotide-binding protein G(s) subunit alpha isoforms short [gi:52000961]
View
35
[SID17389587]
Potency 74.978qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
View
36
[SID17389587]
Potency 74.978qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
View
37
[SID17389587]
Potency 74.978qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
View
38
[SID17389587]
Potency 74.978qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
View
39
[SID17389587]
Potency 74.978qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
View
40
[SID49816673]
Potency 100HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID540317, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
View
41
[SID49816673]
 uHTS identification of small molecule inhibitors of Csn-mediated Deneddylation of Cullin-Ring Ligases, vis a fluorescence polarization assay [AID651999, Type: screening]COPS5 gene product [Homo sapiens] [gi:38027923]
View
42
[SID49816673]
Potency qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
View
43
[SID49816673]
Potency qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
View
44
[SID49816673]
 Activator for delta FosB/delta FosB homodimer Measured in Biochemical System Using Plate Reader - 2072-01_Activator_SinglePoint_HTS_Activity [AID493131, Type: screening]protein fosB [Mus musculus] [gi:6679827]
View
45
[SID49816673]
 uHTS identification of Gli-Sufu Antagonists in a luminescence reporter assay [AID588413, Type: screening]Gli1 [Mus musculus] [gi:6009644]
View
46
[SID49816673]
 uHTS identification of Gli-Sufu Antagonists in a luminescence reporter assay [AID588413, Type: screening]Gli1 [Mus musculus] [gi:6009644]
View
47
[SID49816673]
 Luminescence-based cell-based primary high throughput screening assay to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) [AID624169, Type: screening]Htr2a gene product [Mus musculus] [gi:27753985]
View
48
[SID49816673]
 Luminescence-based cell-based primary high throughput screening assay to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) [AID624169, Type: screening]Htr2a gene product [Mus musculus] [gi:27753985]
View
49
[SID49816673]
Potency qHTS of IL-2 Activators [AID652025, Type: confirmatory]Il2 gene product [Mus musculus] [gi:7110653]
View
50
[SID49816673]
 HTS for developing T Cell Immune Modulators [AID2052, Type: screening]integrin alpha-L [Mus musculus] [gi:124486680]
View