dasatinib (CID 3062316) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(498)
 
 
Inactive(273)
 
 
Inconclusive(54)
 
 
Unspecified(577)
 
 
Top Targets:
PKc(108)
 
 
 
 
PKc like(64)
 
 
 
 
STKc AGC(47)
 
 
 
PTKc Abl(35)
 
 
 
 
PTKc EGFR(34)
 
 
 
BioAssay Types:
Literature(1211)
 
 
 
 
 
Confirmatory(164)
 
 
 
 
 
Screening(18)
 
 
 
BioActivity Types:
Kd(765)
 
 
 
IC50(112)
 
 
 
Potency(56)
 
 
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1066    Data Row: 1402   Total Pages: 29   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103501621]
Kd 1.6e-05Binding constant for ABL1(M351T)-phosphorylated kinase domain [AID624985, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
2
[SID103501621]
Kd 1.6e-05Binding constant for ABL1(M351T)-phosphorylated kinase domain [AID624985, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
3
[SID103501621]
Kd 1.9e-05Binding constant for ABL1(F317L)-phosphorylated kinase domain [AID624982, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
4
[SID103501621]
Kd 1.9e-05Binding constant for ABL1(F317L)-phosphorylated kinase domain [AID624982, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
5
[SID103501621]
Kd 2.5e-05Binding constant for ABL1(H396P)-nonphosphorylated kinase domain [AID624983, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
6
[SID103501621]
Kd 2.5e-05Binding constant for ABL1(H396P)-nonphosphorylated kinase domain [AID624983, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
7
[SID103501621]
Kd 2.9e-05Binding constant for ABL1-nonphosphorylated kinase domain [AID624991, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
8
[SID103501621]
Kd 2.9e-05Binding constant for ABL1-nonphosphorylated kinase domain [AID624991, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
9
[SID103501621]
Kd 3.2e-05Binding constant for ABL1(F317L)-nonphosphorylated kinase domain [AID624981, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
10
[SID103501621]
Kd 3.2e-05Binding constant for ABL1(F317L)-nonphosphorylated kinase domain [AID624981, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
11
[SID103501621]
Kd 3.7e-05Binding constant for ABL1(Q252H)-nonphosphorylated kinase domain [AID624986, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
12
[SID103501621]
Kd 3.7e-05Binding constant for ABL1(Q252H)-nonphosphorylated kinase domain [AID624986, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
13
[SID103501621]
Kd 3.9e-05Binding constant for EPHB6 kinase domain [AID624957, Type: Literature]Ephrin type-B receptor 6 [gi:294862532]
View
14
[SID103501621]
Kd 4.1e-05Binding constant for ABL1(F317I)-phosphorylated kinase domain [AID624980, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
15
[SID103501621]
Kd 4.1e-05Binding constant for ABL1(F317I)-phosphorylated kinase domain [AID624980, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
16
[SID103501621]
Kd 4.6e-05Binding constant for ABL1(H396P)-phosphorylated kinase domain [AID624984, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
17
[SID103501621]
Kd 4.6e-05Binding constant for ABL1(H396P)-phosphorylated kinase domain [AID624984, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
18
[SID103501621]
Kd 4.6e-05Binding constant for ABL1-phosphorylated kinase domain [AID624992, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
19
[SID103501621]
Kd 4.6e-05Binding constant for ABL1-phosphorylated kinase domain [AID624992, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
20
[SID103501621]
Kd 4.7e-05Binding constant for ABL1(E255K)-phosphorylated kinase domain [AID624978, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
21
[SID103501621]
Kd 4.7e-05Binding constant for ABL1(E255K)-phosphorylated kinase domain [AID624978, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
22
[SID103501621]
Kd 5.8e-05Binding constant for ABL1(Y253F)-phosphorylated kinase domain [AID624990, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
23
[SID103501621]
Kd 5.8e-05Binding constant for ABL1(Y253F)-phosphorylated kinase domain [AID624990, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
24
[SID103501621]
Kd 6.4e-05Binding constant for ABL1(Q252H)-phosphorylated kinase domain [AID624987, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
25
[SID103501621]
Kd 6.4e-05Binding constant for ABL1(Q252H)-phosphorylated kinase domain [AID624987, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
26
[SID103501621]
IC50 7e-05Growth inhibition of human M07ep210 cells cells after 48 hrs by [3H]thymidine uptake assay [AID303308, Type: Literature]
View
27
[SID103501621]
Kd 9.3e-05Binding constant for EPHA3 kinase domain [AID625009, Type: Literature]Ephrin type-A receptor 3 [gi:116241351]
View
28
[SID103501621]
Kd 9.3e-05Binding constant for EPHA3 kinase domain [AID625009, Type: Literature]Ephrin type-A receptor 3 [gi:116241351]
View
29
[SID103501621]
Kd 9.3e-05Binding constant for EPHA3 kinase domain [AID435794, Type: Literature]Ephrin type-A receptor 3 [gi:116241351]
View
30
[SID103501621]
Kd 9.3e-05Binding constant for EPHA3 kinase domain [AID435794, Type: Literature]Ephrin type-A receptor 3 [gi:116241351]
View
31
[SID103501621]
Kd 0.0001Binding constant for ABL1(F317I)-nonphosphorylated kinase domain [AID624979, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
32
[SID103501621]
Kd 0.0001Binding constant for ABL1(F317I)-nonphosphorylated kinase domain [AID624979, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
33
[SID103501621]
Kd 0.00017Binding constant for ABL2 kinase domain [AID435777, Type: Literature]Abelson tyrosine-protein kinase 2 [gi:1168268]
View
34
[SID103501621]
Kd 0.00017Binding constant for ABL2 kinase domain [AID435777, Type: Literature]Abelson tyrosine-protein kinase 2 [gi:1168268]
View
35
[SID103501621]
Kd 0.00017Binding constant for ABL2 kinase domain [AID624993, Type: Literature]Abelson tyrosine-protein kinase 2 [gi:1168268]
View
36
[SID103501621]
Kd 0.00017Binding constant for ABL2 kinase domain [AID624993, Type: Literature]Abelson tyrosine-protein kinase 2 [gi:1168268]
View
37
[SID103501621]
IC50 0.0002Inhibition of Fyn [AID271967, Type: Literature]Tyrosine-protein kinase Fyn [gi:125370]
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38
[SID103501621]
IC50 0.0002Inhibition of Fyn [AID271967, Type: Literature]Tyrosine-protein kinase Fyn [gi:125370]
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39
[SID103501621]
Kd 0.0002Binding constant for LCK kinase domain [AID435676, Type: Literature]Tyrosine-protein kinase Lck [gi:125474]
View
40
[SID103501621]
Kd 0.0002Binding constant for LCK kinase domain [AID435676, Type: Literature]Tyrosine-protein kinase Lck [gi:125474]
View
41
[SID103501621]
Kd 0.0002Binding constant for LCK kinase domain [AID625013, Type: Literature]Tyrosine-protein kinase Lck [gi:125474]
View
42
[SID103501621]
Kd 0.0002Binding constant for LCK kinase domain [AID625013, Type: Literature]Tyrosine-protein kinase Lck [gi:125474]
View
43
[SID103501621]
Kd 0.00021Binding constant for SRC kinase domain [AID625016, Type: Literature]Proto-oncogene tyrosine-protein kinase Src [gi:125711]
View
44
[SID103501621]
Kd 0.00021Binding constant for SRC kinase domain [AID625016, Type: Literature]Proto-oncogene tyrosine-protein kinase Src [gi:125711]
View
45
[SID103501621]
Kd 0.00021Binding constant for SRC kinase domain [AID435195, Type: Literature]Proto-oncogene tyrosine-protein kinase Src [gi:125711]
View
46
[SID103501621]
Kd 0.00021Binding constant for SRC kinase domain [AID435195, Type: Literature]Proto-oncogene tyrosine-protein kinase Src [gi:125711]
View
47
[SID103501621]
Kd 0.00021Binding constant for BLK kinase domain [AID624841, Type: Literature]Tyrosine-protein kinase Blk [gi:158936749]
View
48
[SID103501621]
Kd 0.00021Binding constant for BLK kinase domain [AID624841, Type: Literature]Tyrosine-protein kinase Blk [gi:158936749]
View
49
[SID103501621]
Kd 0.00021Binding constant for BLK kinase domain [AID435646, Type: Literature]Tyrosine-protein kinase Blk [gi:158936749]
View
50
[SID103501621]
Kd 0.00021Binding constant for BLK kinase domain [AID435646, Type: Literature]Tyrosine-protein kinase Blk [gi:158936749]
View