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dasatinib (CID 3062316) - Compound BioActivity Data
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BioActivity Outcomes:
Active(834)
 
 
Inactive(340)
 
 
Inconclusive(98)
 
 
Unspecified(736)
 
 
Top Targets:
PKc(95)
 
 
 
 
PKc like(69)
 
 
 
 
PTKc Abl(38)
 
 
 
 
PTKc Src like(37)
 
 
 
PTKc EGFR(35)
 
 
 
 
BioAssay Types:
Literature(1314)
 
 
 
 
 
Confirmatory(609)
 
 
 
 
 
Screening(36)
 
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Kd(765)
 
 
 
IC50(547)
 
 
 
Potency(156)
 
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1652    Data Row: 2008   Total Pages: 101   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103501621]
IC50 1.09e-07SANGER: Inhibition of human BV-173 cell growth in a cell viability assay. [AID741988, Type: confirmatory]
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2
[SID103501621]
IC50 2.66e-07SANGER: Inhibition of human K-562 cell growth in a cell viability assay. [AID742260, Type: confirmatory]
View
3
[SID103501621]
IC50 8.22e-07SANGER: Inhibition of human BL-70 cell growth in a cell viability assay. [AID741982, Type: confirmatory]
View
4
[SID103501621]
IC50 1.08e-06SANGER: Inhibition of human EM-2 cell growth in a cell viability assay. [AID742144, Type: confirmatory]
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5
[SID103501621]
IC50 3.21e-06SANGER: Inhibition of human LAMA-84 cell growth in a cell viability assay. [AID742302, Type: confirmatory]
View
6
[SID103501621]
IC50 9.8e-06SANGER: Inhibition of human MEG-01 cell growth in a cell viability assay. [AID742350, Type: confirmatory]
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7
[SID103501621]
IC50 1.31e-05SANGER: Inhibition of human EoL-1-cell cell growth in a cell viability assay. [AID742166, Type: confirmatory]
View
8
[SID103501621]
Kd 1.6e-05Binding constant for ABL1(M351T)-phosphorylated kinase domain [AID624985, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
9
[SID103501621]
Kd 1.9e-05Binding constant for ABL1(F317L)-phosphorylated kinase domain [AID624982, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
10
[SID103501621]
Kd 2.5e-05Binding constant for ABL1(H396P)-non phosphorylated kinase domain [AID624983, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
11
[SID103501621]
Kd 2.9e-05Binding constant for ABL1-non phosphorylated kinase domain [AID624991, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
12
[SID103501621]
Kd 3.2e-05Binding constant for ABL1(F317L)-non phosphorylated kinase domain [AID624981, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
13
[SID103501621]
Kd 3.7e-05Binding constant for ABL1(Q252H)-non phosphorylated kinase domain [AID624986, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
14
[SID103501621]
Kd 3.9e-05Binding constant for EPHB6 kinase domain [AID624957, Type: Literature]Ephrin type-B receptor 6 [gi:294862532]
View
15
[SID103501621]
IC50 4.04e-05SANGER: Inhibition of human CTV-1 cell growth in a cell viability assay. [AID742089, Type: confirmatory]
View
16
[SID103501621]
Kd 4.1e-05Binding constant for ABL1(F317I)-phosphorylated kinase domain [AID624980, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
17
[SID103501621]
Kd 4.6e-05Binding constant for ABL1(H396P)-phosphorylated kinase domain [AID624984, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
18
[SID103501621]
Kd 4.6e-05Binding constant for ABL1-phosphorylated kinase domain [AID624992, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
19
[SID103501621]
Kd 4.7e-05Binding constant for ABL1(E255K)-phosphorylated kinase domain [AID624978, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
20
[SID103501621]
Kd 5.8e-05Binding constant for ABL1(Y253F)-phosphorylated kinase domain [AID624990, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View