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metribuzin (CID 30479) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(1)
 
 
Inactive(213)
 
 
Inconclusive(10)
 
 
Unspecified(1)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD AR(16)
 
 
NR LBD ER(16)
 
 
 
NR LBD Fxr(10)
 
 
NR LBD GR(10)
 
 
BioAssay Types:
Confirmatory(156)
 
 
 
 
Summary(48)
 
 
Literature(2)
 
 
Screening(1)
 
 
BioActivity Types:
Potency(191)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 131    Data Row: 225   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26757266]
Potency 39.8107qHTS assay for small molecule agonists of retinoid X receptor alpha signaling [AID588544, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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2
[SID26757266]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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3
[SID26757266]
Potency-Replicate_1 70.7946qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
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4
[SID26757266]
Potency qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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5
[SID144211048]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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6
[SID144211048]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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7
[SID144211048]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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8
[SID144209204]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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9
[SID144209204]
Potency-Replicate_1 qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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10
[SID144209204]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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11
[SID144209204]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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12
[SID144209204]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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13
[SID144209204]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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14
[SID144209204]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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15
[SID144209204]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
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16
[SID144209204]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
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17
[SID144209204]
Potency-Replicate_1 qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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18
[SID144209204]
Potency-Replicate_1 qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
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19
[SID144209204]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cells [AID720687, Type: confirmatory]
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20
[SID144209204]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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21
[SID144209204]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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22
[SID144209204]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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23
[SID144209204]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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24
[SID144209204]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cell free culture [AID720681, Type: confirmatory]
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25
[SID144209204]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cell free culture [AID720682, Type: confirmatory]
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26
[SID144209204]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cell free culture [AID720683, Type: confirmatory]
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27
[SID144209204]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cell free culture [AID720684, Type: confirmatory]
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28
[SID144209204]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cell free culture [AID720685, Type: confirmatory]
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29
[SID144209204]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cell free culture [AID720686, Type: confirmatory]
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30
[SID144209204]
Ratio Potency (uM) qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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31
[SID144209204]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cells [AID720674, Type: confirmatory]
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32
[SID144209204]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cells [AID720675, Type: confirmatory]
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33
[SID144209204]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cells [AID720678, Type: confirmatory]
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34
[SID144209204]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cells [AID720679, Type: confirmatory]
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35
[SID144209204]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cells [AID720680, Type: confirmatory]
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36
[SID26757266]
Potency qHTS assay for cell viability of HEK293 cells [AID743288, Type: confirmatory]
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37
[SID26757266]
Potency qHTS assay for cell viability of the p53RE-bla HCT-116 cell line [AID743292, Type: confirmatory]
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38
[SID144209204]
Potency-Replicate_1 qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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39
[SID144209204]
Potency-Replicate_1 qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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40
[SID144209204]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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41
[SID144209204]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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42
[SID26757266]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
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43
[SID26757266]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_5, Type: other]
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44
[SID26757266]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_6, Type: other]
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45
[SID26757266]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
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46
[SID26757266]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_8, Type: other]
View
47
[SID26757266]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity - cell viability counter screen [AID720653, Type: confirmatory]
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48
[SID144211048]
Potency-Replicate_1 qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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49
[SID144211048]
Potency-Replicate_1 qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
View
50
[SID144211048]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
View