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azoxystrobin (CID 3034285) - Compound BioActivity Data
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BioActivity Outcomes:
Active(65)
 
 
Inactive(65)
 
 
Inconclusive(59)
 
 
Unspecified(270)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD ER(9)
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD Fxr(6)
 
 
 
 
BioAssay Types:
Literature(299)
 
 
 
 
Confirmatory(106)
 
 
 
 
 
Summary(24)
 
 
 
 
Screening(6)
 
 
 
BioActivity Types:
Potency(121)
 
 
 
 
IC50(8)
 
 
 
Ki(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 450    Data Row: 459   Total Pages: 23   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170481149]
IC50 0.0112Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain C, Crystal Structure Analysis Of Bovine Bc1 With Azoxystrobin [gi:55669766]
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2
[SID170481149]
IC50 0.0112Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain C, Crystal Structure Analysis Of Bovine Bc1 With Azoxystrobin [gi:55669766]
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3
[SID144214048]
Potency-Replicate_1 0.0731qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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4
[SID144214048]
Potency-Replicate_1 0.0731qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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5
[SID144214048]
Potency-Replicate_1 0.0821qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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6
[SID103526766]
IC50 0.12Inhibition of cytochrome bc1 complex in bovine heart mitochondria by NADH oxidase assay [AID346928, Type: Literature]
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7
[SID103526766]
Ki 0.2042Competitive inhibition of pig heart Cytochrome b-c1 complex using DBH2 as substrate by Line-weaverBurk plot analysis [AID611602, Type: Literature]
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8
[SID144214048]
Potency 0.2169qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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9
[SID144214048]
Potency 0.2434qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID103526766]
IC50 0.2913Non-competitive inhibition of pig heart succinate-cytochrome c reductase (Electron transport protein complex 2/3) using cytochrome c as substrate by Line-weaverBurk plot analysis [AID611599, Type: Literature]
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11
[SID103526766]
Ki 0.2976Inhibition of Sus scrofa (pig) heart cytochrome bc1 complex using DBH2 as substrate by spectrophotometric analysis [AID1091872, Type: Literature]Cytochrome b [gi:6166075]
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12
[SID144214048]
Potency-Replicate_1 0.4113qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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13
[SID103526766]
IC50 0.43471Competitive inhibition of pig heart Cytochrome b-c1 complex using DBH2 as substrate in absence of lauryl maltoside by Line-weaverBurk plot analysis [AID611600, Type: Literature]
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14
[SID103526766]
IC50 0.52712Competitive inhibition of pig heart Cytochrome b-c1 complex using DBH2 as substrate in presence of lauryl maltoside by Line-weaverBurk plot analysis [AID611601, Type: Literature]
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15
[SID144214048]
TR Potency (uM) 0.721897qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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16
[SID144214048]
Potency-Replicate_1 2.3131qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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17
[SID103526766]
IC50 3.256DNDI: Inhibition of Chagas Disease parasite Trypanosoma cruzi (Tulahuen LacZ, Clone C4), in vitro. [AID623858, Type: confirmatory]
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18
[SID103526766]
Km 4.37Activity of pig heart succinate-cytochrome c reductase (Electron transport protein complex 2/3) using cytochrome c as substrate by Line-weaverBurk plot analysis [AID611606, Type: Literature]
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19
[SID144214048]
Ratio Potency (uM) 4.42197qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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20
[SID144214048]
Potency-Replicate_1 4.6153qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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