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azoxystrobin (CID 3034285) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(51)
 
 
Inactive(49)
 
 
Inconclusive(56)
 
 
Unspecified(26)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD ER(9)
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD Fxr(6)
 
 
 
 
BioAssay Types:
Confirmatory(103)
 
 
 
 
 
Literature(36)
 
 
 
Summary(24)
 
 
 
 
Screening(6)
 
 
 
BioActivity Types:
Potency(120)
 
 
 
 
IC50(6)
 
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 174    Data Row: 182   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144214048]
Potency-Replicate_1 0.0731qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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2
[SID144214048]
Potency-Replicate_1 0.0731qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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3
[SID144214048]
Potency-Replicate_1 0.0821qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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4
[SID103526766]
IC50 0.12Inhibition of cytochrome bc1 complex in bovine heart mitochondria by NADH oxidase assay [AID346928, Type: Literature]
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5
[SID103526766]
Ki 0.2042Competitive inhibition of pig heart Cytochrome b-c1 complex using DBH2 as substrate by Line-weaverBurk plot analysis [AID611602, Type: Literature]
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6
[SID144214048]
Potency 0.2169qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID144214048]
Potency 0.2434qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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8
[SID103526766]
IC50 0.2913Non-competitive inhibition of pig heart succinate-cytochrome c reductase (Electron transport protein complex 2/3) using cytochrome c as substrate by Line-weaverBurk plot analysis [AID611599, Type: Literature]
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9
[SID144214048]
Potency-Replicate_1 0.4113qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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10
[SID103526766]
IC50 0.43471Competitive inhibition of pig heart Cytochrome b-c1 complex using DBH2 as substrate in absence of lauryl maltoside by Line-weaverBurk plot analysis [AID611600, Type: Literature]
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11
[SID103526766]
IC50 0.52712Competitive inhibition of pig heart Cytochrome b-c1 complex using DBH2 as substrate in presence of lauryl maltoside by Line-weaverBurk plot analysis [AID611601, Type: Literature]
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12
[SID144214048]
TR Potency (uM) 0.721897qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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13
[SID144214048]
Potency-Replicate_1 2.3131qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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14
[SID103526766]
IC50 3.256DNDI: Inhibition of Chagas Disease parasite Trypanosoma cruzi (Tulahuen LacZ, Clone C4), in vitro. [AID623858, Type: other]
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15
[SID103526766]
Km 4.37Activity of pig heart succinate-cytochrome c reductase (Electron transport protein complex 2/3) using cytochrome c as substrate by Line-weaverBurk plot analysis [AID611606, Type: Literature]
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16
[SID144214048]
Ratio Potency (uM) 4.42197qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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17
[SID144214048]
Potency-Replicate_1 4.6153qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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18
[SID144214048]
Potency-Replicate_1 5.2231qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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19
[SID144214048]
Potency-Replicate_1 7.3148qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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20
[SID144214048]
AR Potency (uM) 7.89012qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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21
[SID26757224]
Potency 13.6854qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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22
[SID144214048]
Potency-Replicate_1 16.5169qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
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23
[SID144214048]
Potency-Replicate_1 19.3312qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
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24
[SID144214048]
Potency-Replicate_1 21.6899qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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25
[SID144214048]
Potency 22.3872qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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26
[SID144214048]
Potency-Replicate_1 23.3307qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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27
[SID144214048]
Potency 28.1838qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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28
[SID144214048]
Potency-Replicate_1 32.6741qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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29
[SID144214048]
Potency-Replicate_1 46.5509qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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30
[SID144214048]
Potency-Replicate_1 58.1036qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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31
[SID144214048]
Potency-Replicate_1 73.1481qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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32
[SID103526766]
DNDI: Inhibition of Chagas Disease parasite Trypanosoma cruzi (Tulahuen LacZ, Clone C4), in vitro. [AID623860, Type: other]
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33
[SID26757224]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
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34
[SID26757224]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
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35
[SID26757224]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_3, Type: other]
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36
[SID26757224]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
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37
[SID26757224]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_5, Type: other]
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38
[SID26757224]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_6, Type: other]
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39
[SID26757224]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
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40
[SID26757224]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_8, Type: other]
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41
[SID103526766]
Fungistatic activity against Fusarium proliferatum at 30 uM after 72 hrs by microtiter plate assay [AID297550, Type: Literature]
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42
[SID103526766]
Fungistatic activity against Fusarium solani at 30 uM after 72 hrs by microtiter plate assay [AID297552, Type: Literature]
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43
[SID103526766]
Fungistatic activity against Fusarium oxysporum at 30 uM after 72 hrs by microtiter plate assay [AID297555, Type: Literature]
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44
[SID103526766]
Inhibition of Blumeria graminis f. sp. Tritici cytochrome bc1 complex inoculated in wheat plant assessed as lowest drug concentration required to control 100% disease applied to leaf 1 hr prior inoculation measured after 6 to 9 days [AID346923, Type: Literature]
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45
[SID103526766]
Inhibition of Mycosphaerella graminicola cytochrome bc1 complex inoculated in wheat plant assessed as lowest drug concentration required to control 100% disease applied to leaf 1 hr prior inoculation measured after 6 to 9 days [AID346924, Type: Literature]
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46
[SID103526766]
Inhibition of Phytophthora infestans cytochrome bc1 complex inoculated in tomato plant assessed as lowest drug concentration required to control 100% disease applied to leaf 1 hr prior inoculation measured after 6 to 9 days [AID346925, Type: Literature]
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47
[SID103526766]
Inhibition of Plasmopara viticola cytochrome bc1 complex inoculated in vine plant assessed as lowest drug concentration required to control 100% disease applied to leaf 1 hr prior inoculation measured after 6 to 9 days [AID346926, Type: Literature]
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48
[SID103526766]
Inhibition of Puccinia triticina cytochrome bc1 complex inoculated in wheat plant assessed as lowest drug concentration required to control 100% disease applied to leaf 1 hr prior inoculation measured after 6 to 9 days [AID346927, Type: Literature]
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49
[SID85860338]
Inhibition of P. falciparum Dd2 [AID2302, Type: screening]lactate dehydrogenase [Plasmodium falciparum] [gi:111034851]
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50
[SID85860338]
Inhibition of P. falciparum 3D7 [AID2306, Type: screening]L-lactate dehydrogenase [Plasmodium falciparum 3D7] [gi:124513266]
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