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BioActivity Data for Compound neohesperidin dihydrochalcone (CID 30231)

BioActivity Outcomes:
Inactive(245)
 
 
Inconclusive(9)
 
 
Unspecified(9)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD ER(9)
 
 
NR LBD AR(9)
 
 
NR LBD TR(7)
 
 
NR LBD VDR(6)
 
 
BioAssay Types:
Confirmatory(218)
 
 
 
Summary(26)
 
 
Literature(10)
 
 
 
BioAssay Categories:
In vitro(2)
 
 
Toxicity(36)
 
 
 
ADME(2)
 
 
Cell-based(2)
 
 
BioActivity Types:
Potency(202)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 251    Data Row: 263   Total Pages: 14   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103759732]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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2
[SID103759732]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
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3
[SID103759732]
Sensory evaluation was done for sweetness at a concentration of 250 p.p.m. against sample intensity relative to 10% sucrose. [AID89764, Type: Literature]
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4
[SID103759732]
Sensory evaluation was done for sweetness at a concentration of 250 p.p.m. against compound potency calculated on a molar basis. [AID90088, Type: Literature]
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5
[SID103759732]
Sensory evaluation was done for sweetness at a concentration of 250 p.p.m. against compound potency calculated on weight basis. [AID90226, Type: Literature]
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6
[SID103759732]
Sensory evaluation was done at a concentration of 250 p.p.m. against other properties. [AID90264, Type: Literature]
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7
[SID103759732]
Sensory evaluation was done at a concentration of 250 p.p.m. against property of bitterness. [AID90265, Type: Literature]
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8
[SID103759732]
Sensory evaluation was done at a concentration of 250 p.p.m. against property of sweetness. [AID90266, Type: Literature]
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9
[SID17388867]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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10
[SID17388867]
Potency qHTS assay for cell viability of HEK293 cells [AID743288, Type: confirmatory]
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11
[SID17388867]
Potency qHTS assay for cell viability of the p53RE-bla HCT-116 cell line [AID743292, Type: confirmatory]
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12
[SID17388867]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity - cell viability counter screen [AID720653, Type: confirmatory]
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13
[SID17388867]
Potency-Replicate_1 qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID720652, Type: confirmatory]
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14
[SID17388867]
Potency qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 5 hr assay [AID651755, Type: confirmatory]
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15
[SID17388867]
Potency qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 1 hr assay [AID651754, Type: confirmatory]
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16
[SID144207501]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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17
[SID144207501]
Ratio Potency (uM) qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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18
[SID17388867]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity [AID720636, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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19
[SID17388867]
Potency qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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20
[SID17388867]
Potency qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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