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BioActivity Data for Compound neohesperidin dihydrochalcone (CID 30231)

BioActivity Outcomes:
Inactive(248)
 
 
Inconclusive(9)
 
 
Unspecified(9)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD ER(9)
 
 
NR LBD AR(9)
 
 
NR LBD TR(7)
 
 
NR LBD VDR(6)
 
 
BioAssay Types:
Confirmatory(220)
 
 
 
Summary(27)
 
 
Literature(10)
 
 
 
BioAssay Categories:
In vitro(2)
 
 
Toxicity(36)
 
 
 
ADME(2)
 
 
Cell-based(2)
 
 
BioActivity Types:
Potency(205)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 254    Data Row: 266   Total Pages: 14   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103759732]
Sensory evaluation was done for sweetness at a concentration of 250 p.p.m. against sample intensity relative to 10% sucrose. [AID89764, Type: Literature]
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2
[SID103759732]
Sensory evaluation was done for sweetness at a concentration of 250 p.p.m. against compound potency calculated on a molar basis. [AID90088, Type: Literature]
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3
[SID103759732]
Sensory evaluation was done for sweetness at a concentration of 250 p.p.m. against compound potency calculated on weight basis. [AID90226, Type: Literature]
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4
[SID103759732]
Sensory evaluation was done at a concentration of 250 p.p.m. against other properties. [AID90264, Type: Literature]
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5
[SID103759732]
Sensory evaluation was done at a concentration of 250 p.p.m. against property of bitterness. [AID90265, Type: Literature]
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6
[SID103759732]
Sensory evaluation was done at a concentration of 250 p.p.m. against property of sweetness. [AID90266, Type: Literature]
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7
[SID17388867]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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8
[SID103759732]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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9
[SID103759732]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
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10
[SID144207501]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the NFkB signaling pathway - cell viability counter screen [AID1159515, Type: confirmatory]
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11
[SID144207501]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the endoplasmic reticulum stress response signaling pathway - cell viability counter screen [AID1159517, Type: confirmatory]
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12
[SID144207501]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID1159520, Type: confirmatory]
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13
[SID144207501]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the AP-1 signaling pathway - cell viability counter screen [AID1159525, Type: confirmatory]
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14
[SID144207501]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the AP-1 signaling pathway [AID1159526, Type: confirmatory]
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15
[SID17388867]
Potency qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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16
[SID17388867]
Potency qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease [AID2101, Type: confirmatory]glucocerebrosidase [Homo sapiens] [gi:496369]
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17
[SID17388867]
Potency qHTS Assay for Inhibitors and Activators of Human alpha-Galactosidase From Spleen Homogenate [AID2107, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
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18
[SID17388867]
Potency qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-7 [AID889, Type: confirmatory]Caspase-7 [gi:1730092]
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19
[SID17388867]
Potency qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase, partial [Homo sapiens] [gi:1832253]
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20
[SID17388867]
JNK3 AlphaScreen Assay [AID530, Type: confirmatory]Mitogen-activated protein kinase 10 [gi:2499604]
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