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BioActivity Data for Compound neohesperidin dihydrochalcone (CID 30231)

BioActivity Outcomes:
Inactive(251)
 
 
Inconclusive(10)
 
 
Unspecified(9)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD ER(9)
 
 
NR LBD AR(9)
 
 
NR LBD TR(7)
 
 
NR LBD VDR(6)
 
 
BioAssay Types:
Confirmatory(222)
 
 
 
Summary(29)
 
 
Literature(10)
 
 
 
BioAssay Categories:
In vitro(2)
 
 
Toxicity(36)
 
 
 
ADME(2)
 
 
Cell-based(2)
 
 
BioActivity Types:
Potency(209)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 258    Data Row: 270   Total Pages: 14   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17388867]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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2
[SID103759732]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
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3
[SID103759732]
Sensory evaluation was done for sweetness at a concentration of 250 p.p.m. against compound potency calculated on weight basis. [AID90226, Type: Literature]
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4
[SID103759732]
Sensory evaluation was done for sweetness at a concentration of 250 p.p.m. against compound potency calculated on a molar basis. [AID90088, Type: Literature]
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5
[SID103759732]
Sensory evaluation was done for sweetness at a concentration of 250 p.p.m. against sample intensity relative to 10% sucrose. [AID89764, Type: Literature]
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6
[SID103759732]
Sensory evaluation was done at a concentration of 250 p.p.m. against other properties. [AID90264, Type: Literature]
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7
[SID103759732]
Sensory evaluation was done at a concentration of 250 p.p.m. against property of sweetness. [AID90266, Type: Literature]
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8
[SID103759732]
Sensory evaluation was done at a concentration of 250 p.p.m. against property of bitterness. [AID90265, Type: Literature]
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9
[SID103759732]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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10
[SID144207501]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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11
[SID17388867]
Potency Cell Viability - LYMP2-011 [AID969, Type: confirmatory]
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12
[SID17388867]
Potency qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 [Homo sapiens] [gi:31542939]
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13
[SID17388867]
Potency qHTS Assay for Identification of Small Molecule Inducers of Hypoxia Response [AID2120, Type: confirmatory]hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) [Homo sapiens] [gi:32879895]
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14
[SID17388867]
qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Red Fluorophore) [AID880, Type: confirmatory]guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1 [Homo sapiens] [gi:33946324]
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15
[SID17388867]
Potency qHTS assay for small molecule activators of the nuclear factor-kappa B (NF-kB) signaling pathway [AID651749, Type: confirmatory]nuclear factor NF-kappa-B p105 subunit isoform 1 [Homo sapiens] [gi:34577122]
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16
[SID144207501]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743227, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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17
[SID144207501]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743212, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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18
[SID144207501]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743226, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
19
[SID144207501]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743215, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
20
[SID144207501]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743199, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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