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Diazepam (CID 3016) - Compound BioActivity Data
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BioActivity Outcomes:
Active(850)
 
 
Inactive(403)
 
 
Inconclusive(110)
 
 
Unspecified(2420)
 
 
Top Targets:
Neur chan LBD(756)
 
 
 
 
Neur chan mem..(268)
 
 
 
 
7TM GPCR Srx(26)
 
 
 
7TM GPCR Srsx(24)
 
 
 
 
NR LBD PPAR(22)
 
 
 
BioAssay Types:
Literature(1887)
 
 
 
 
 
Confirmatory(384)
 
 
 
 
 
Screening(118)
 
 
 
Summary(48)
 
 
 
 
BioActivity Types:
IC50(568)
 
 
 
 
 
Ki(379)
 
 
 
Potency(229)
 
 
 
 
EC50(27)
 
 
 
 
Kd(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2729    Data Row: 3783   Total Pages: 190   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103164353]
Ki 0.0018Inhibition of [3H]diazepam binding to GABA-A central benzodiazepine receptor of rat brain homogenate [AID40969, Type: Literature]
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2
[SID103164353]
Ki 0.0021Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr,gly,val)beta2gamma2 subunits expressed in HEK293 cells [AID220448, Type: Literature]Gamma-aminobutyric acid receptor subunit gamma-2 [gi:120788]
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3
[SID103164353]
Ki 0.0021Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr,gly,val)beta2gamma2 subunits expressed in HEK293 cells [AID220448, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-6 [gi:232127]
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4
[SID103164353]
Ki 0.0021Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr,gly,val)beta2gamma2 subunits expressed in HEK293 cells [AID220448, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-2 [gi:52000957]
View
5
[SID103164353]
IC50 0.00286Displacement of [3H]flumazenil from GABAA/BZD receptor in Sprague-Dawley rat cortical membrane after 35 mins by competition binding assay [AID1072088, Type: Literature]
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6
[SID103164353]
Ki 0.0029In vitro binding affinity against benzodiazepine receptor using [3H]diazepam as radioligand [AID40970, Type: Literature]
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7
[SID103164353]
Ki 0.0029Inhibition of [3H]diazepam binding to GABA-A central benzodiazepine receptor of rat brain homogenate [AID40968, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-2 [gi:120758]
View
8
[SID103164353]
Ki 0.0029Inhibition of [3H]diazepam binding to GABA-A central benzodiazepine receptor of rat brain homogenate [AID40968, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-3 [gi:120761]
View
9
[SID103164353]
Ki 0.0029Inhibition of [3H]diazepam binding to GABA-A central benzodiazepine receptor of rat brain homogenate [AID40968, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-4 [gi:120763]
View
10
[SID103164353]
Ki 0.0029Inhibition of [3H]diazepam binding to GABA-A central benzodiazepine receptor of rat brain homogenate [AID40968, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-5 [gi:120764]
View
11
[SID103164353]
Ki 0.0029Inhibition of [3H]diazepam binding to GABA-A central benzodiazepine receptor of rat brain homogenate [AID40968, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-3 [gi:52000955]
View
12
[SID103164353]
Ki 0.0029Inhibition of [3H]diazepam binding to GABA-A central benzodiazepine receptor of rat brain homogenate [AID40968, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-2 [gi:52000957]
View
13
[SID103164353]
Ki 0.0029Inhibition of [3H]diazepam binding to GABA-A central benzodiazepine receptor of rat brain homogenate [AID40968, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-1 [gi:51317298]
View
14
[SID103164353]
Ki 0.0029Inhibition of [3H]diazepam binding to GABA-A central benzodiazepine receptor of rat brain homogenate [AID40968, Type: Literature]GABA theta subunit [gi:81902501]
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15
[SID103164353]
Ki 0.0029Inhibition of [3H]diazepam binding to GABA-A central benzodiazepine receptor of rat brain homogenate [AID40968, Type: Literature]Gamma-aminobutyric acid receptor subunit delta [gi:544363]
View
16
[SID103164353]
Ki 0.0029Inhibition of [3H]diazepam binding to GABA-A central benzodiazepine receptor of rat brain homogenate [AID40968, Type: Literature]Gamma-aminobutyric acid receptor subunit pi [gi:3023821]
View
17
[SID103164353]
Ki 0.0029Inhibition of [3H]diazepam binding to GABA-A central benzodiazepine receptor of rat brain homogenate [AID40968, Type: Literature]Gamma-aminobutyric acid receptor subunit epsilon [gi:13959374]
View
18
[SID103164353]
Ki 0.0029Inhibition of [3H]diazepam binding to GABA-A central benzodiazepine receptor of rat brain homogenate [AID40968, Type: Literature]Gamma-aminobutyric acid receptor subunit gamma-3 [gi:120790]
View
19
[SID103164353]
Ki 0.0029Inhibition of [3H]diazepam binding to GABA-A central benzodiazepine receptor of rat brain homogenate [AID40968, Type: Literature]Gamma-aminobutyric acid receptor subunit gamma-2 [gi:120788]
View
20
[SID103164353]
Ki 0.0029Inhibition of [3H]diazepam binding to GABA-A central benzodiazepine receptor of rat brain homogenate [AID40968, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-6 [gi:232127]
View