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Zeranol (CID 2999413) - Compound BioActivity Data
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BioActivity Outcomes:
Active(65)
 
 
Inactive(1141)
 
 
Inconclusive(111)
 
 
Unspecified(10)
 
 
Top Targets:
7TM GPCR Srx(26)
 
 
 
7TM GPCR Srsx(23)
 
 
 
NR LBD PPAR(19)
 
 
 
NR LBD ER(19)
 
 
 
 
NR LBD AR(16)
 
 
 
 
BioAssay Types:
Screening(609)
 
 
 
 
Confirmatory(552)
 
 
 
 
 
Literature(94)
 
 
 
 
 
Summary(39)
 
 
 
 
BioActivity Types:
Potency(455)
 
 
 
 
 
IC50(60)
 
 
 
 
 
EC50(13)
 
 
 
AC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1034    Data Row: 1327   Total Pages: 67   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103597643]
EC50 0.024Agonist activity at ERbeta by fluorescence polarization assay [AID356007, Type: Literature]
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2
[SID17389521]
Potency 0.1413qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID144208401]
Potency-Replicate_1 0.175qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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4
[SID144208401]
Ratio Potency (uM) 0.407237qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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5
[SID144204524]
Ratio Potency (uM) 0.727057qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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6
[SID144204524]
Potency-Replicate_1 0.8485qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
7
[SID3715954]
IC50 2.6462Tumor Hsp90 Inhibitors Dose Response Confirmation [AID712, Type: confirmatory]heat shock protein HSP 90-alpha isoform 2 [Homo sapiens] [gi:154146191]
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8
[SID3715954]
IC50 2.6462Tumor Hsp90 Inhibitors Dose Response Confirmation [AID712, Type: confirmatory]90-kda heat shock protein beta HSP90 beta [Homo sapiens] [gi:4261762]
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9
[SID17389521]
Potency 3.9811qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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10
[SID144208401]
Potency-Replicate_1 6.9078qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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11
[SID3715954]
Potency 7.3078qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504467, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
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12
[SID144208401]
Ratio Potency (uM) 9.03665qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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13
[SID144204524]
Potency-Replicate_1 9.4392qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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14
[SID144204524]
Ratio Potency (uM) 10.1922qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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15
[SID144208401]
Ratio Potency (uM) 11.044qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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16
[SID17389521]
Potency 11.9955Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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17
[SID49674197]
Potency 14.581qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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18
[SID144204524]
Ratio Potency (uM) 16.2927qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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19
[SID144204524]
Potency-Replicate_1 16.7855qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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20
[SID49674197]
Potency 18.3564qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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