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BioActivity Data for Compound SMR000068628 (CID 2998182)

BioActivity Outcomes:
Active(6)
 
 
Inactive(806)
 
 
Inconclusive(37)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(49)
 
 
 
alkPPc(16)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(11)
 
 
PTPc(9)
 
 
BioAssay Types:
Screening(556)
 
 
 
 
Confirmatory(263)
 
 
 
 
 
Literature(11)
 
 
BioAssay Categories:
In vitro(2)
 
 
In vivo(1)
 
 
Biochemical(119)
 
 
Toxicity(12)
 
 
Cell-based(139)
 
 
 
Organism-base..(11)
 
 
BioActivity Types:
Potency(176)
 
 
 
 
 
IC50(52)
 
 
 
EC50(12)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 776    Data Row: 850   Total Pages: 43   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID3712827]
Potency 0.2453qHTS Assay for Agonists of the Relaxin Receptor RXFP1: V1B Hit Validation [AID492948, Type: confirmatory]vasopressin V1b receptor [Homo sapiens] [gi:4502333]
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2
[SID3712827]
Potency 0.2752qHTS Assay for Agonists of the Relaxin Receptor RXFP1: RXFP2 Hit Validation [AID489043, Type: confirmatory]relaxin receptor 2 isoform 1 [Homo sapiens] [gi:18677729]
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3
[SID3712827]
Potency 12.5893qHTS Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase [AID1631, Type: confirmatory]pyruvate kinase PKM isoform a [Homo sapiens] [gi:33286418]
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4
[SID3712827]
Potency 35.4813qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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5
[SID3712827]
CYP2C9 Assay [AID777, Type: screening]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
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6
[SID3712827]
Cell signaling CRE-BLA (Fsk stim) [AID662, Type: confirmatory]
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7
[SID24839801]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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8
[SID24839801]
Potency 2.5119qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS [AID624288, Type: confirmatory]Guanine nucleotide-binding protein G(s) subunit alpha isoforms short [gi:52000961]
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9
[SID3712827]
Potency 10qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a [AID927, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
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10
[SID3712827]
Potency 12.5893qHTS Assay for Inhibitors of Human Muscle isoform 2 Pyruvate Kinase [AID1634, Type: confirmatory]pyruvate kinase PKM isoform a [Homo sapiens] [gi:33286418]
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11
[SID24839801]
Potency 89.1251HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID540317, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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12
[SID3712827]
Potency qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2 as the Reporter [AID463254, Type: confirmatory]ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692]
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13
[SID3712827]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. [AID1415, Type: screening]regulator of G-protein signaling 4 [Homo sapiens] [gi:86301151]
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14
[SID24839801]
Potency Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS [AID504845, Type: confirmatory]regulator of G-protein signaling 4 [Homo sapiens] [gi:86301163]
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15
[SID24839801]
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay [AID624354, Type: screening]tumor necrosis factor receptor superfamily member 10B isoform 1 precursor [Homo sapiens] [gi:224494019]
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16
[SID3712827]
IC50 uHTS identification of small molecule inhibitors of LYP via a fluorescence intensity assay [AID1779, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 22 isoform 1 [Homo sapiens] [gi:224586929]
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17
[SID3712827]
LYP Activators-an Autoimmunity Target - Primary screen [AID697, Type: screening]tyrosine-protein phosphatase non-receptor type 22 isoform 1 [Homo sapiens] [gi:224586929]
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18
[SID3712827]
LYP Inhibitors-an Autoimmunity Target - Primary screen [AID640, Type: screening]tyrosine-protein phosphatase non-receptor type 22 isoform 1 [Homo sapiens] [gi:224586929]
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19
[SID3712827]
HTS for LYP Inhibitors-an Autoimmunity Target - Primary screen [AID606, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 22 isoform 1 [Homo sapiens] [gi:224586929]
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20
[SID24839801]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of human platelet-activating factor acetylhydrolase 1B, catalytic subunit 3 (PAFAH1B3) [AID492972, Type: screening]platelet-activating factor acetylhydrolase IB subunit gamma [Homo sapiens] [gi:225543099]
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