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Chlordecone (CID 299) - Compound BioActivity Data
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BioActivity Outcomes:
Active(326)
 
 
Inactive(585)
 
 
Inconclusive(385)
 
 
Unspecified(10)
 
 
Top Targets:
NR LBD PPAR(31)
 
 
 
 
NR LBD ER(21)
 
 
 
NR LBD AR(20)
 
 
 
 
NR LBD TR(18)
 
 
 
 
7TM GPCR Srx(18)
 
 
 
BioAssay Types:
Confirmatory(568)
 
 
 
 
 
Screening(305)
 
 
 
Summary(48)
 
 
 
 
Literature(22)
 
 
 
 
BioActivity Types:
Potency(517)
 
 
 
 
 
IC50(10)
 
 
 
AC50(2)
 
 
Kd(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 636    Data Row: 1306   Total Pages: 66   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103589666]
Kd 0.49Displacement of [3H]-estradiol (E2) from sheep uterine estrogen receptor [AID69702, Type: Literature]Estrogen receptor beta [gi:13124234]
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2
[SID103589666]
Kd 0.49Displacement of [3H]-estradiol (E2) from sheep uterine estrogen receptor [AID69702, Type: Literature]Estrogen receptor [gi:1706709]
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3
[SID144208790]
Potency-Replicate_1 0.536qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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4
[SID144210418]
Potency-Replicate_1 0.5853qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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5
[SID144208790]
Ratio Potency (uM) 0.905569qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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6
[SID144210418]
Ratio Potency (uM) 1.00162qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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7
[SID144208790]
Potency-Replicate_1 1.9017qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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8
[SID56462801]
AC50_uM 2.685HsHsp90 Counterscreen Measured in Microorganism System Using Plate Reader - 2121-02_Inhibitor_Dose_CherryPick_Activity [AID540270, Type: confirmatory]heat shock protein HSP 90-alpha isoform 2 [Homo sapiens] [gi:154146191]
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9
[SID56462801]
AC50_uM 2.93Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_Dose_CherryPick_Activity [AID540268, Type: confirmatory]HSP90 [Plasmodium falciparum 3D7] [gi:124809506]
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10
[SID17388955]
Potency 3.3491qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 1 hr assay [AID651754, Type: confirmatory]
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11
[SID144208790]
Potency-Replicate_1 3.3818qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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12
[SID17388955]
Potency 4.2163qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 5 hr assay [AID651755, Type: confirmatory]
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13
[SID56462801]
Potency 4.4668qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode) [AID624417, Type: confirmatory]glp-1 receptor [Homo sapiens] [gi:1724069]
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14
[SID144208790]
Ratio Potency (uM) 6.2983qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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15
[SID144208790]
Potency-Replicate_1 6.8043qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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16
[SID17388955]
Potency 7.9433qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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17
[SID56462801]
CC50 8.692Cytotoxicity screening for potential Inhibitors of Bacterial Capsule Biogenesis [AID493020, Type: confirmatory]
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18
[SID17388955]
Potency 9.4392qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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19
[SID17389843]
Potency 9.4392qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 5 hr assay [AID651755, Type: confirmatory]
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20
[SID144208790]
Potency-Replicate_1 9.5311qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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