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Deferoxamine (CID 2973) - Compound BioActivity Data
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BioActivity Outcomes:
Active(45)
 
 
Inactive(319)
 
 
Inconclusive(13)
 
 
Unspecified(206)
 
 
Top Targets:
7TM GPCR Srx(12)
 
 
7TM GPCR Srsx(11)
 
 
CAP ED(5)
 
 
RasGEF(4)
 
 
Troponin(4)
 
 
BioAssay Types:
Literature(262)
 
 
 
 
 
Screening(232)
 
 
 
 
Confirmatory(82)
 
 
 
 
 
BioActivity Types:
Potency(75)
 
 
 
 
 
IC50(35)
 
 
 
 
EC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 541    Data Row: 583   Total Pages: 30   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103178524]
GI50 2.9Antitrypanosomal activity against Trypanosoma brucei TC211 after 24 hrs by alamar blue assay [AID736793, Type: Literature]
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2
[SID103178524]
IC50 3.4Antimalarial activity against liver stages of Plasmodium falciparum after 96 hrs [AID683724, Type: Literature]
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3
[SID103178524]
IC50 4.4Induction of iron chelating activity by calcein fluorescence assay [AID460069, Type: Literature]
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4
[SID103178524]
IC50 4.51Antiproliferative activity against human SK-N-MC cells after 72 hrs by MTT assay [AID292406, Type: Literature]
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5
[SID103178524]
IC50 5Antiproliferative activity against human SK-N-MC cells after 72 hrs by MTT assay [AID439762, Type: Literature]
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6
[SID103178524]
IC50 7.35Antiproliferative activity against human SK-N-MC cells after 72 hrs by MTT assay [AID370485, Type: Literature]
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7
[SID103178524]
IC50 7.5Antiproliferative activity at human A549 cells after 72 hrs by MTT assay [AID716220, Type: Literature]
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8
[SID103178524]
IC50 8.58Antiproliferative activity against human SK-N-MC cells after 96 hrs by MTT assay [AID271691, Type: Literature]
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9
[SID103178524]
IC50 9.49Toxicity in MDCK cells by MTT method [AID460409, Type: Literature]
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10
[SID103178524]
IC50 9.89Cytotoxicity against human SK-N-MC cells after 72 hrs by MTT assay [AID476194, Type: Literature]
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11
[SID103178524]
IC50 10Iron chelating activity by ferrozine method [AID312353, Type: Literature]
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12
[SID103178524]
IC50 10Antiproliferative activity at human DMS53 cells after 72 hrs by MTT assay [AID716221, Type: Literature]
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13
[SID103178524]
IC50 10Antiproliferative activity at human SK-N-MC cells after 72 hrs by MTT assay [AID716225, Type: Literature]
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14
[SID93577020]
Potency 11.5821qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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15
[SID103178524]
IC50 12.05Antiproliferative activity against human SK-MN-C cells by MTT assay [AID312544, Type: Literature]
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16
[SID103178524]
IC50 12.5Antiproliferative activity against human SK-N-MC cells after 72 hrs by MTT assay [AID677905, Type: Literature]
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17
[SID103178524]
IC50 14.22Antiproliferative activity against human SK-N-MC cells by MTT assay [AID303514, Type: Literature]
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18
[SID103178524]
IC50 16.04Toxicity in human SK-N-MC cells by MTT method [AID460410, Type: Literature]
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19
[SID103178524]
IC50 17.07Antiproliferative activity against human SK-N-MC cells after 72 hrs by MTT assay [AID539493, Type: Literature]
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20
[SID103178524]
IC50 17.07Antiproliferative activity against human SK-N-MC cells after 72 hrs by MTT assay [AID671698, Type: Literature]
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