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CID2950007 (CID 2950007) - Compound BioActivity Data
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BioActivity Outcomes:
Probe(1)
 
 
Active(35)
 
 
Inactive(678)
 
 
Inconclusive(43)
 
 
Unspecified(7)
 
 
Top Targets:
7tm 4(41)
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
ABC ATPase(10)
 
 
 
Rac1 like(9)
 
 
 
BioAssay Types:
Screening(463)
 
 
 
 
 
Confirmatory(238)
 
 
 
 
 
Literature(12)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(158)
 
 
 
 
 
IC50(39)
 
 
 
EC50(36)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 674    Data Row: 764   Total Pages: 39   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID57578341]
Project utilizing multiplex HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases [AID1772, Type: summary]ras protein, partial [Homo sapiens] [gi:190938]
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2
[SID57644019]
EC50_MICROM 0.263Dose Response of compounds with constant GTP under the condition of nascent nucleotide depletion and Mg buffer [AID2376, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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3
[SID24796017]
Potency 0.5805A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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4
[SID57578341]
EC50_MICROM 0.704Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype [AID1337, Type: confirmatory]Ras-related protein Rab-2A [gi:46577642]
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5
[SID24796017]
EC50_MICROM 0.7042Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype [AID1337, Type: confirmatory]Ras-related protein Rab-2A [gi:46577642]
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6
[SID57578341]
EC50_MICROM 0.823SAR compounds for Cdc42 probe extension project tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype, round 1 [AID588377, Type: confirmatory]cell division control protein 42 homolog isoform 1 precursor [Homo sapiens] [gi:4757952]
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7
[SID57578341]
EC50_MICROM 1.89SAR compounds for Cdc42 probe extension project tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant, round 1 [AID588373, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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8
[SID24796017]
EC50 2.829Luminescence Cell-Based/Microorganism Dose Confirmation HTS to Identify Inhibitors of T.Cruzi Replication. [AID2044, Type: confirmatory]
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9
[SID24796017]
EC50_MICROM 3.198Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID1334, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
View
10
[SID57578341]
EC50_MICROM 3.2Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID1334, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
View
11
[SID24796017]
EC50_MICROM 8.039Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant [AID1333, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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12
[SID57578341]
EC50_MICROM 8.04Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant [AID1333, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
View
13
[SID24796017]
Potency 9.5283qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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14
[SID24796017]
Potency 13.1154Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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15
[SID24796017]
Potency 16.3601A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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16
[SID57644019]
PAK-Effector Pull-down Assay for Quantification of Rac/Cdc42 Activation Using 3T3 Cells [AID2374, Type: other]p21 activated kinase 1B [Homo sapiens] [gi:3265160]
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17
[SID118043962]
Actin Polymerization inhibition by compounds from Cdc42 Probe Extension Project [AID652107, Type: other]actin, cytoplasmic 1 [Homo sapiens] [gi:4501885]
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18
[SID24796017]
384-well Z-Lyte format Hck-Nef inhibitor HTS run at the PMLSC [AID463187, Type: screening]
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19
[SID57644019]
Panel results of Cell based ELISA Assessing Activation of Cdc42 and Rac1 [AID2375_1, Type: other]
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20
[SID57644019]
Panel results of Cell based ELISA Assessing Activation of Cdc42 and Rac1 [AID2375_2, Type: other]
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